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Contents: April 2007, Volume 2007, Annual Meeting   [Index by Author] 

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AACR Annual Meeting-- Apr 14-18, 2007; Los Angeles, CA

Cox-2 and Selenium: Poster Presentations:Back

Sunil Prabhu, Naveen Kanthamneni, and Jeffrey Wang
Synergistic chemoprevention of colorectal cancer using colon-targeted polymer nanoparticles
AACR Meeting Abstracts 2007 2007: 1.  

SubbaRao Madhunapantula, Arati Sharma, Sung Jin Huh, Dhimant Desai, Krishnegowda Gowdahalli, Shantu Amin, and Gavin Robertson
Development of a novel iNOS inhibitor that retards melanoma metastasis
AACR Meeting Abstracts 2007 2007: 2.  

Anjia Han, Zibo Song, Chang Tong, Tianhong Li, Barbara Heerdt, Leonard Augenlicht, and Wancai Yang
Sulindac suppressed beta-catenin expression in human malignant cell lines
AACR Meeting Abstracts 2007 2007: 3.  

Shahar Lev-Ari, Alexander Starr, Olga Polansky, Victoriya Karaush, Akiva Vexler, Isac Schnirer, Joel Greif, Dan Aderka, and Rami Ben-Yosef
The inhibition of growth of orthotopic human non-small cell lung cancer in athymic mice by curcumin is associated with inhibition of COX-2 and p-Erk1/2.
AACR Meeting Abstracts 2007 2007: 4.  

James Talmadge, Moses Donkor, Eric Scholar, Sherry Westphal, Bela Toth, Rakesh Singh, Traci Hoke, Alicia Dafferner, and Joyce Solheim
The role of immature myeloid suppressor cells in tumor growth and chemoprevention
AACR Meeting Abstracts 2007 2007: 5.  

Jong-Sik Kim, Seong-Ho Lee, Seung Joon Baek, Eul-Won Seo, and Thomas Eling
Caffeic acid phenethyl ester up-regulates non-steroidal anti-inflammatory drug activated gene via activating transcription factor 3
AACR Meeting Abstracts 2007 2007: 6.  

Dawn Holt, Xinrong Ma, Namita Kundu, and Amy Fulton
Targeting the EP4 receptor for prostaglandin E2 increases natural killer cell lytic activity and inhibits metastasis
AACR Meeting Abstracts 2007 2007: 7.  

Yubin Hao, Tianpei Xie, Yanfei Zhou, Dan Zhang, Xiaowu Pang, Rajagopalan Sridhar, Joseph Califano, and Xinbin Gu
Comparison of salvianolic acid B and celecoxib effects on nontumorogenic BPH1 and tumorogenic BPH1CAFTD1 human prostate cell lines
AACR Meeting Abstracts 2007 2007: 8.  

Alexandar Bank, Jian Yu, and Lin Zhang
SMAC mimetics enhance NSAID-induced apoptosis and overcome NSAID resistance in colon cancer cells
AACR Meeting Abstracts 2007 2007: 9.  

Keiichi Suzuki, Kunhua Fan, Kan Yang, Claudia Gravaghi, Sergio Lamprecht, Peter Holt, Levy Kopelovich, and Martin Lipkin
Sulindac rapidly induces inflammation and neoplasms in the intestine of A/J mice
AACR Meeting Abstracts 2007 2007: 10.  

Chinthalapally Rao, Malisetty Swamy, Chang Choi, Naveena Janakiram, Jagan Patlolla, and Vernon Steele
Chemoprevention of colon carcinogenesis by licofelone, a novel dual 5-LOX/COX inhibitor, in F344 rats
AACR Meeting Abstracts 2007 2007: 11.  

Jie Liao, Gary Lu, Allison Yang, Meng Zhang, Liang Yan, and Guang-Yu Yang
Inhibition of chronic ulcerative colitis-induced carcinoma development by 5-lipoxygenase inhibitor-Zileuton and cyclooxygenase-2 inhibitor-Celecoxib and their combination
AACR Meeting Abstracts 2007 2007: 12.  

Jeong-Sang Lee, Hyun Soo Kim, Joydeb Kundu, Ki-Baik Hahm, Robert Langenbach, and Young-Joon Surh
Attenuation of dextran sulfate sodium-pomoted mouse colon carcinogenesis by pharmacologic and genetic inhibition of COX-2
AACR Meeting Abstracts 2007 2007: 13.  

Fu-Li Yu, Abdul Gapor, Wanda Bender, and Katarzyna Berbaka
Compare the preventive effect of alpha-tocopherol, alpha-, gamma-, and delta-tocotrienols on the formation of aflatoxin B1 (AFB1) epoxide and the potential to prevent liver cancer carcinogenesis at the initiation
AACR Meeting Abstracts 2007 2007: 14.  

Leslie Gapter, Lawrence Ng, Gowsala Sivam, and Howard Hosick
Water-soluble garlic constituents inhibit breast cancer growth in vitro and in vivo
AACR Meeting Abstracts 2007 2007: 15.  

Zhe Wang, Hongbo Hu, Guang-Xun Li, Cheng Jiang, Sung-Hoon Kim, and Junxuan Lu
Mechanisms of methyl-selenium against vascular endothelial proliferation and tumor angiogenesis
AACR Meeting Abstracts 2007 2007: 16.  

Hema Vunta, Dhimant Desai, Lalitha Guruprasad, C. Channa Reddy, Karam El-Bayoumy, Gavin Robertson, Shantu Amin, and K. Sandeep Prabhu
Chemopreventive activity of selenium derivatives of celecoxib
AACR Meeting Abstracts 2007 2007: 17.  

Anna Powolny, Dong Xiao, Karen Lew, Young-Ae Kim, Yan Zeng, Eun-Ryeong Hahm, Rajiv Dhir, and Shivendra Singh
Diallyl trisulfide inhibits growth of PC-3 human prostate cancer xenografts in vivo in association with induction of multidomain proapoptotic proteins Bax and Bak
AACR Meeting Abstracts 2007 2007: 18.  

Dorrelyn Patacsil, Sylvester Osayi, Prafulla Gokhale, Mukesh Verma, Robert Clarke, and Deepak Kumar
Vitamin E succinate induces apoptosis in pancreatic cancer cells
AACR Meeting Abstracts 2007 2007: 19.  

Yan Dong and Shuang Liu
Molecular mechanisms underlying selenium suppression of androgen receptor signaling in prostate cancer cells
AACR Meeting Abstracts 2007 2007: 20.  

Young-Ae Kim, Dong Xiao, Hui Xiao, Anna Powolny, Karen Lew, Megan Reilly, Yan Zeng, and Shivendra Singh
Critical role of Bax and Bak and reactive oxygen species in mitochondria-mediated apoptosis by garlic-derived cancer chemopreventive agent diallyl trisulfide
AACR Meeting Abstracts 2007 2007: 21.  

Hwa Jin Jung, Ju Han Lee, Jung Won Hwang, Seok Won Jung, Sung-Goo Chang, and Young Seo
The novel chemopreventive evidence for selenomethionine (SeMet) against methyl methanesulfonate (MMS): Redox modulation of tumor suppressor p53 in SeMet-induced base excision repair (BER)
AACR Meeting Abstracts 2007 2007: 22.  

Rayudu Gopalakrishna, Jason Schiffman, Nandakishor Kapa, Harry Mai, and Usha Gundimeda
Induction of cell death in precancer prostate epithelial cells by enhanced proteolysis of selenium oxidized cell survival protein kinase C isoenzymes
AACR Meeting Abstracts 2007 2007: 23.  

Junxuan Lu, Guang-Xun Li, Hyo-Jeong Lee, Zhe Wang, Hongbo Hu, Lei Wang, Cheng Jiang, Sung-Hoon Kim, Jennifer Watts, and Gerald Combs
Superior in vivo inhibitory efficacy of methyl-selenium than selenomethionine or selenite against human prostate cancer
AACR Meeting Abstracts 2007 2007: 24.  

Nur Ozten Kandas, Lori Horton, Sally Lasano, and Maarten Bosland
Selenomethionine does not protect against prostate cancer in male NBL rats treated with testosterone and estradiol-17β
AACR Meeting Abstracts 2007 2007: 25.  

Shuang Liu, James Marshall, Clement Ip, and Yan Dong
Down-regulation of telomerase by selenium in prostate cancer cells
AACR Meeting Abstracts 2007 2007: 26.  

Kun-Ming Chen, Thomas Spratt, Bruce Stanley, Dhimant Desai, Arunangshu Das, Shantu Amin, and Karam El-Bayoumy
Inhibition of NF-{kappa}B-DNA binding by organoselenocyanate through covalent modification of the p50 subunit: structure elucidation by MALDI-TOF-MS/MS analysis
AACR Meeting Abstracts 2007 2007: 27.  

Hye-Kyung Na, Eun-Hee Kim, Min-Ah Choi, Do-Hee Kim, and Young-Joon Surh
Diallyl trisulfide inhibits IKKβ-NF-{kappa}B signaling and induces apoptosis in human breast cancer cells through generation of ROS
AACR Meeting Abstracts 2007 2007: 28.  

Diane Harris, Marc Tobias, Aune Moro, Yantao Niu, Qing-Yi Lu, Navindra Seeram, David Heber, and Vay Liang Go
Lack of effect of Scutellaria baicalensis- or baicalin-supplemented diets on intestinal tumorigenesis in vivo
AACR Meeting Abstracts 2007 2007: 29.  

Magdalena Kowalczyk, Zbigniew Walaszek, Piotr Kowalczyk, Thomas Slaga, and Margaret Hanausek
Antiproliferative and proapoptotic effects of selected antioxidants in murine skin cancer prevention.
AACR Meeting Abstracts 2007 2007: 30.  

Future Leaders, New Directions-- Highlighting the Work of Outstanding Early-Career Scientists: Oral Presentations - Invited Abstracts:Back

Angela Ting
RNA-mediated epigenetic silencing in human cancers
AACR Meeting Abstracts 2007 2007: AMC-01.  

Jing Huang
Lysine methylation and demethylation of p53
AACR Meeting Abstracts 2007 2007: AMC-02.  

Kimberly Christensen
Six1 promotes breast cancer metastasis via upregulation of the lymphangiogenic factor VEGF-C
AACR Meeting Abstracts 2007 2007: AMC-03.  

Cyrus Ghajar
Validation of a novel, 3-D model to quantify tumor invasion in a metastatic microenvironment
AACR Meeting Abstracts 2007 2007: AMC-04.  

Maxence Nachury
The primary cilium: A signaling organelle
AACR Meeting Abstracts 2007 2007: AMC-06.  

New Drugs on the Horizon 1: Oral Presentations - Invited Abstracts:Back

Steven Elmore
ABT-263: An orally bioavailable Bcl-2 family protein inhibitor
AACR Meeting Abstracts 2007 2007: ND-1.  

Dirk Heerding, Nelson Rhodes, Jack Leber, Anthony Choudhry, Tammy Clark, Nestor Concha, Derek Duckett, Derek Eberwein, Robert Geske, Tona Gilmer, Pearl Huang, Jason Kahana, Richard Keenan, Elena Kleymenova, Victoria Knick, Louis Lafrance, Zhihong Lai, Timothy Lansing, Mei Li, Elisabeth Minthorn, Kimberly Robell, David Rusnak, Igor Safonov, Edgar Wood, and Rakesh Kumar
Identification of a novel inhibitor of AKT kinase, GSK690693.
AACR Meeting Abstracts 2007 2007: ND-2.  

Michel Maira
Biochemical, cellular and in vivo profiling of a new PI3K inhibitor from the imidazoquinoline series
AACR Meeting Abstracts 2007 2007: ND-3.  

New Drugs on the Horizon 2: Oral Presentations - Invited Abstracts:Back

W. Gregory Roberts, Ethan Ung, Pamela Whalen, Christofer Autry, Martin Berliner, Kevin Coleman, Beth Cooper, Earling Emerson, Matt Griffor, Catherine Hulford, Tom Hynes, John Kath, Susan LaGreca, Jing Lin, Marianne Lorenzen, Michael Luzzio, Eric Marr, Luis Martinez-Alsina, Jay Pandit, Nandini Patel, Daniel Richter, Felix Vajdos, Matthew Wessel, and Lili Yao
Nonclinical pharmacological characterization of a focal adhesion kinase inhibitor, PF-562,271
AACR Meeting Abstracts 2007 2007: ND-4.  

Susan Ashwell
AZD7762, a novel potent and selective inhibitor of checkpoint kinases
AACR Meeting Abstracts 2007 2007: ND-5.  

Growth factors: Poster Presentations - Late-Breaking Abstracts:Back

Luke Wanami and Robin Bachelder
The vascular endothelial growth factor regulates Snail expression in breast tumors: Implications for tumor progression
AACR Meeting Abstracts 2007 2007: LB-9.  

Receptors: Poster Presentations - Late-Breaking Abstracts:Back

Nikolaos Dallas, Michael Gray, Ling Xia, George Van Buren, Sherry Lim, Fan Fan, and Lee Ellis
Neuropilin-2 mediates survival, migration and invasion in gastrointestinal tumor cells
AACR Meeting Abstracts 2007 2007: LB-10.  

H. Shepard
Pan-HER ligand traps and possible new therapeutics for cancer
AACR Meeting Abstracts 2007 2007: LB-11.  

Cell signaling: Poster Presentations - Late-Breaking Abstracts:Back

Hildegard Schuller, Mourad Majidi, and Hussein Al-Wadei
The GABA-B receptor (GABA-BR) is a novel drug target for the treatment and prevention of pancreatic cancer.
AACR Meeting Abstracts 2007 2007: LB-12.  

Eduardo Parra and Juan Inostroza
Inhibition of Egr-1 expression in prostate cancer cells using siRNA activate apoptosis mediated by decreased activities of NF-{kappa}B and AP-1 factors.
AACR Meeting Abstracts 2007 2007: LB-13.  

Roberto Piva, Elisa Pellegrino, Valentina Grosso, Andrea Manazza, Francesco Boccalatte, Valeria Poli, Antonino Neri, Roberto Chiarle, and Giorgio Inghirami
Dissection of critical pathways for Anaplastic Lymphoma Kinase transformation
AACR Meeting Abstracts 2007 2007: LB-14.  

Suresh Veeramani, Ta-Chun Yuan, Fen-Fen Lin, and Ming-Fong Lin
p66Shc, a novel redox protein, regulates androgen-stimulated prostate cancer cell proliferation
AACR Meeting Abstracts 2007 2007: LB-15.  

Meng Qiao, James Iglehart, and Arthur Pardee
Metastatic potential of 21T human breast cancer cells depends on Akt/PKB activation
AACR Meeting Abstracts 2007 2007: LB-16.  

Li-Jin Hsu, Lori Schultz, and Nan-Shan Chang
TIAF1 is essential for Smad phosphorylation and nuclear translocation in the TGF-β signal pathway
AACR Meeting Abstracts 2007 2007: LB-17.  

Hiroyuki Nakamura, Shingo Dan, Tetsuyuki Akashi, Michiyo Okui, Shinichi Egawa, Yuichi Ishikawa, Michiaki Unno, and Takao Yamori
Ectopic expression of PIK3CD in human cancer cell lines and human lung carcinoma
AACR Meeting Abstracts 2007 2007: LB-18.  

Geetika Chakravarty, Adrian Lee, and Jeffrey Myers
Essential role of Insulin like growth factor receptor signaling in transcriptional regulation of Id1 and Id2 in follicular thyroid carcinoma
AACR Meeting Abstracts 2007 2007: LB-19.  

Hae Kyung Lee, Cunli Xiang, Simona Cazacu, Susan Finniss, and Chaya Brodie
RasGRP3 regulates the activation of ras and rap1 and the migration of glioma cells
AACR Meeting Abstracts 2007 2007: LB-20.  

Michael Degtyarev, Ann De Maziere, Christine Orr, Jie Lin, Janet Tien, Wei Prior, Brian Lee, Howard Stern, Lesley Murray, Judith Klumperman, Klaus Hoeflich, Lori Friedman, and Kui Lin
Dissecting the requirement of Akt isoforms in tumor growth and maintenance using inducible shRNA knockdown
AACR Meeting Abstracts 2007 2007: LB-22.  

Susan Finniss, Cathie Miller, Hae Kyung Lee, Cunli Xiang, Simona Cazacu, and Chaya Brodie
PKC gamma is downregulated in gliomas and inhibits glioma cell growth in vitro and in vivo
AACR Meeting Abstracts 2007 2007: LB-23.  

Yu-Ming Chang, Lanfang Bai, Joy Yang, Hsing-Jien Kung, and Christopher Evans
AZD0530 is a Novel Src Inhibitor with Anti-Proliferation and Anti-Migration Properties in Prostate Cancer
AACR Meeting Abstracts 2007 2007: LB-24.  

Theodore Chung, William Broaddus, Ashraf Khalil, Asad Khan, and Kristoffer Valerie
The effects of ERB-B1/2 inhibitor, AEE-788 tobacco alkaloid, nicotine, on EGFR expression and phosphorylation and cell growth in U87 malignant glioma cells.
AACR Meeting Abstracts 2007 2007: LB-25.  

Michael Hancock, Kaitlyn VanDenHeuvel-Kramer, Connie Lebakken, David Lasky, Kun Bi, Randy Hoffman, Richard Somberg, Tammy Turek-Etienne, Chris Armstrong, and Brian Pollok
Multi-pathway profiling approach to compound validation: utilizing SelectScreenTM cell-based pathway screening to characterize pathway selectivity for commonly used protein kinase inhibitors
AACR Meeting Abstracts 2007 2007: LB-26.  

Jeong Hee Jeon, Yoon Soo Chang, Se Kyu Kim, Hyung Jung Kim, Joon Chang, Chul Min Ahn, and Sung Kyu Kim
The effects of insulin-receptor substrate-1 regulation on cell cycle in NSCLC
AACR Meeting Abstracts 2007 2007: LB-375.  

Tumor-stromal cell interactions: Poster Presentations - Late-Breaking Abstracts:Back

Danbin Li, Emily Hoag, Robert Bell, and Michael Cox
Stromal cell production of IGFBP-5 promotes IGF-dependent prostate cancer cell growth and survival
AACR Meeting Abstracts 2007 2007: LB-27.  

Protein and lipid kinases: Poster Presentations - Late-Breaking Abstracts:Back

James Hnilo, Michael Harges, and Joanne Birkner
MDS Signature, a new Fast KinaseTM database tool for the rapid profiling of chemical compounds.
AACR Meeting Abstracts 2007 2007: LB-28.  

Protein and lipid phosphatases: Poster Presentations - Late-Breaking Abstracts:Back

Amit Verma, Sushovan Guha, Dimpy Koul, Huamin Wang, and Kapil Mehta
Regulation of tumor suppressor protein PTEN by tissue transglutaminase: prognostic significance in pancreatic cancer
AACR Meeting Abstracts 2007 2007: LB-29.  

James Peacock, Stephen Ip, Michael Cox, Ramon Parsons, Marcus Peter, and Christopher Ong
PTEN inactivation promotes mitochondrial dependent Fas-induced apoptosis through PEA-15
AACR Meeting Abstracts 2007 2007: LB-30.  

Survivorship, Quality of Life, and Supportive Care: Poster Presentations:Back

Michael Frass, Sandra Schranz, Helmut Friehs, Chistine Marosi, Gabriela Kornek, Peter Chiba, and Christoph Zielinski
First experience of additional treatment with homeopathy in patients with cancer
AACR Meeting Abstracts 2007 2007: 31.  

Jun Nie, Guang Ru Xie, Shu Jun Liu, and Guo Zhu Xu
The study of dosage titration about morphine analgesic effect and the reliability and effectiveness about NMDA receptor antagonist (Dextromethmorphan) which improve the analgesic effect of morphine
AACR Meeting Abstracts 2007 2007: 32.  

Giovanni Mantovani, Antonio Maccio', Clelia Madeddu, Giulia Gramignano, Roberto Serpe, Elena Massa, Giorgio Astara, Giovanna Lamonica, Carla Spiga, and Francesca Tanca
A randomized phase III clinical study with an integrated treatment in cancer-related anorexia/cachexia: Evaluation of laboratory variables of treatment efficacy
AACR Meeting Abstracts 2007 2007: 33.  

Elizabeth Kvale, Olivio Clay, Lesley Ross, Jocelyn McGee, Jerri Edwards, Carla Falkson, and Karlene Ball
Cognitive and functional impairment in older cancer survivors
AACR Meeting Abstracts 2007 2007: 34.  

Phillip Phan and Ani Khodavirdi
Successful treatment of chemotherapy-induced peripheral neuropathy (CIPN) with spinal cord stimulation (SCS): case reports
AACR Meeting Abstracts 2007 2007: 35.  

Francesca Sampogna, Marina Frontani, Giannandrea Baliva, Gabriele Alvetreti, Cristina Di Pietro, Stefano Tabolli, Giandomenico Russo, and Damiano Abeni
Quality of life, psychological distress, and alexithymia in patients with cutaneous lymphoma
AACR Meeting Abstracts 2007 2007: 36.  

Meinolf Karthaus, S Schulte-Martini, C Scherb, E Kuhlmann, N Pfeil, K Tagizadeh, and M Trapp
Psycho-oncological screening followed by risk adjusted psychological intervention in patients with newly diagnosed or relapsing cancer
AACR Meeting Abstracts 2007 2007: 37.  

Signaling and new technologies: Poster Presentations - Late-Breaking Abstracts:Back

Katherine Gillis, Dianne Fishwild, Lynn Zieske, and Amedeo Cappione
Single cell profiling of phosphoprotein signaling cascades using GuavaFLO, a cytometry-based system for multidimensional cellular analysis.
AACR Meeting Abstracts 2007 2007: LB-31.  

Miscellaneous topics: Poster Presentations - Late-Breaking Abstracts:Back

Xiangdong Zhou, James Coad, Barbara Ducatman, and Yehenew Agazie
SHP2 is Overexpressed in Breast Cancer Cells and in Infiltrating Ductal Carcinoma of the Breast, Implying its Involvement in Breast Cancer Development
AACR Meeting Abstracts 2007 2007: LB-32.  

Karen Kelly-Spratt, Jeannette Philippe-Staheli, Kay Gurley, Kyung Hoon-Kim, and Christopher Kemp
Reduction of p27Kip1 in lung tumorigenesis is mediated by Ras-Akt signaling and is reversible
AACR Meeting Abstracts 2007 2007: LB-72.  

Yuemeng Dai, Paul Spring, and Brendan Stack
Metallopanstimulin-1 regulates head and neck cancer cell growth in vivo
AACR Meeting Abstracts 2007 2007: LB-73.  

Takashi Mine, Satoko Matsueda, Hiroshi Tokumitsu, Constantin Ioannides, and David Chang
Elimination of drug-resistant cancer stem-like cells (C-St-C) by Notch and Numb-peptide activated T cells.
AACR Meeting Abstracts 2007 2007: LB-97.  

Sergio Koifman
Evidence on the association of birth weight and infant acute leukemia
AACR Meeting Abstracts 2007 2007: LB-124.  

Alison Mondul, Patrick Walsh, and Elizabeth Platz
Association of statin use with pathologic findings on prostatectomy and prostate cancer progression
AACR Meeting Abstracts 2007 2007: LB-125.  

Karin Ekstrom Smedby, Claire Vajdic, Michael Falster, Eric Engels, Otoniel Martinez-Maza, Jennifer Turner, Andrew Grulich, Wendy Cozen, and on behalf of The International Lymphoma Epidemiology Consortium
Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: a pooled analysis
AACR Meeting Abstracts 2007 2007: LB-126.  

Christopher Haiman, Nick Patterson, Matthew Freedman, Alicja Waliszewska, Julie Neubauer, Gavin McDonald, Christine Schirmer, Arti Tandon, Simon Myers, Daniel Stram, Malcolm Pike, Loic Le Marchand, Laurence Kolonel, Melissa Frasco, David Wong, Loreall Pooler, Kristin Ardlie, Esther John, Ingrid Oakley-Girvan, Alice Whittemore, Kathleen Cooney, Sue Ingles, David Altshuler, Brian Henderson, and David Reich
Three regions at 8q24 independently contribute risk for prostate cancer
AACR Meeting Abstracts 2007 2007: LB-134.  

Xianling Cong, Liying Wang, and Yongli Yu
Detection and Clinical Assesement of Human Papillomaviruses in Condyloma Acuminatum Lesions by PCR-RFLP and DNA Sequencing
AACR Meeting Abstracts 2007 2007: LB-136.  

Ratna Chakrabarti, Jennifer Jones, Denise Oelschlager, Tenekua Tapia, Albert Tousson, and William Grizzle
Phosphorylated LIM Kinases colocalize with gamma-tubulin in centrosomes during early stages of mitosis
AACR Meeting Abstracts 2007 2007: LB-228.  

Pamela Moore, Clement Yedjou, and Paul Tchounwou
Malathion induced genotoxicity and modulation of p-53, and Bcl-2 in human liver carcinoma (HePG2) cells
AACR Meeting Abstracts 2007 2007: LB-232.  

Ekaterina Frank and Roger Woodgate
Altered catalytic activity and fidelity of human DNA polymerase iota in the presence of manganese
AACR Meeting Abstracts 2007 2007: LB-233.  

Kelly McCann, Tatiana Spicakova, Marsha Williamson, John Game, and J. Martin Brown
Yeast Bre1 and Dot1 histone modification enzymes are necessary for efficient homologous recombination repair
AACR Meeting Abstracts 2007 2007: LB-234.  

Ramesh Balusu, Melissa Armas, Aruna Jaiswal, Chanakya Kundu, and Satya Narayan
Structural basis of interaction of adenomatous polyposis coli (APC) with DNA polymerase β and its implications for base excision repair
AACR Meeting Abstracts 2007 2007: LB-235.  

Suying Lu and Michael Archer
Coordination of fatty acid synthesis and cell proliferation by transcription factor Sp1 in MCF-7 human breast cancer cells
AACR Meeting Abstracts 2007 2007: LB-237.  

Manuel Valenzuela, Lan Hu, Jamshed Rahman, Pierre Maission, and Paul Meltzer
Mapping Initiation Sites for Human DNA Replication along 100 kb regions in both Chr2q34 and Chr3q26
AACR Meeting Abstracts 2007 2007: LB-248.  

Xailin Wu, Paola Quinones-Olson, Claudia Stewart, Cindy Kim, Nicole Lum, Kris Pike, Terry Plona, and David Munroe
A 300K cancer gene sequencing microarray for mutation detection.
AACR Meeting Abstracts 2007 2007: LB-249.  

Andersen Tim, Bill Crowley, Robert Davis, Ullysses Eoff, Marc Footen, Richard Newman, Tim Otter, Mason Vail, Lian Zhu, and David Zuercher
Virtual tissue models for studying cancer mechanisms
AACR Meeting Abstracts 2007 2007: LB-257.  

Puei Nam Tay, Tze Chin Tan, Mirtha Laban, Carol Ho-Wing Leung, and Shing Chuan Hooi
Genes associated with epithelial-mesenchymal transition (EMT) of metastatic human colon cancer cells and the possible cross-talk with the PI3K/Akt and Erk signaling pathways
AACR Meeting Abstracts 2007 2007: LB-280.  

Mark Berardini
A new approach to automated affinity tagged protein purification
AACR Meeting Abstracts 2007 2007: LB-305.  

Toshiro Shirakawa, Akinobu Gotoh, Shuji Terao, Nobuyuki Hinata, Kazumasa Goda, Kazushi Tanaka, Atsushi Takenaka, Isao Hara, Chinghai Kao, Thomas Gardner, Leland Chung, Sadao Kamidono, and Masato Fujisawa
Results of a phase I/II study of Ad-OC-TK/VAL gene therapy for the patients with metastatic or local recurrent prostate cancer
AACR Meeting Abstracts 2007 2007: LB-357.  

Autophagy: Poster Presentations - Late-Breaking Abstracts:Back

Guanghua Wan, Zhaorigetu Siqin, Cara Farrell, Qian Li, and Chien-An Hu
Synergistic killing effect of apolipoprotein L1 and L2 in cancer cells
AACR Meeting Abstracts 2007 2007: LB-33.  

Cell death receptors/apoptotic signaling pathways: Poster Presentations - Late-Breaking Abstracts:Back

Urs von Holzen, Stephan Vorburger, Young-Jin Suh, Yanna Liu, Xiaolin Lu, Khandan Keyomarsi, Stephen Swisher, and Kelly Hunt
E2F-1 upregulates PKR by binding to the PKR promoter in human breast cancer cells
AACR Meeting Abstracts 2007 2007: LB-34.  

Vidya Mamidipudi and Christine Cartwright
RACK1 induces apoptosis of colon cells by inhibiting Src in the intrinsic and the Akt pathway
AACR Meeting Abstracts 2007 2007: LB-35.  

Joseph Bauer, Joseph Lupica, Bei Morrison, Heidi Schmidt, Zhuo Tang, Rebecca Haney, Rhonda Oates, Rebecca Lee, Joseph DiDonato, and Daniel Lindner
Nitrosylcobalamin potentiates the anti-neoplastic effects of chemotherapeutic agents via suppression of survival signaling
AACR Meeting Abstracts 2007 2007: LB-36.  

Effectors of apoptosis: Poster Presentations - Late-Breaking Abstracts:Back

Koji Yamamoto, Motohiro Mihara, Koji Kubota, and Shinichi Miyagawa
Mitochondria- targeted p53 has tumor suppressor activity in subcutaneous tumor model of human colon cancer cell line
AACR Meeting Abstracts 2007 2007: LB-37.  

Zhaorigetu Siqin, Guanghua Wan, Ramesh Kaini, and Chien-An Hu
Upregulation of apolipoprotein L6 and L1, two BH3-only pro-death proteins, by p53 in cancer cells
AACR Meeting Abstracts 2007 2007: LB-38.  

Epidemiologic Methods, Risk Factors, and Incidence: Poster Presentations:Back

Julie cunningham, Thomas Sellers, JoEllen Schildkraut, Catherine Phelan, Ed Iversen, Lynn Hartmann, Yifan Huang, Linda Kelemen, Janet Olson, Mark Liebow, Robert Vierkant, Zachary Fredericksen, Brian Calingaert, Madhura Gadre, V Pankrantz, and Ellen Goode
Perfomance of WGA DNA in an Illumina GoldenGate BeadArray assay
AACR Meeting Abstracts 2007 2007: 38.  

Jian Wang, Kwong Wong, Kai Yan, Wing-Yuk Chow, Chris Man, Rudy Guerra, and Ching Lau
Identification of large-scale copy number variations in normal population using SNP array
AACR Meeting Abstracts 2007 2007: 39.  

Garry Larson, David Smith, Ola Snove, Carlotta Glackin, Theodore Krontiris, Cathryn Lundberg, and Guillermo Rivas
Integrating gene arrays, breast cancer families, and evolutionary genomics to identify new disease genes for risk assessment
AACR Meeting Abstracts 2007 2007: 40.  

Haukur Gunnarsson, Goran Jonsson, Adalgeir Arason, Bjarni Agnarsson, Oskar Johannsson, Johan Vallon-Christersson, Johan Staaf, Hakan Olsson, Ake Borg, and Rosa Barkardottir
Mapping of genomic aberrations using array-CGH of breast tumors from families with germline mutations in BRCA1 and BRCA2 genes and high risk breast cancer families without BRCA1/2 mutations
AACR Meeting Abstracts 2007 2007: 41.  

Todd Boren, Catherine Phelan, Yifan Huang, Mark Liebow, Zachary Fredericksen, Vernon Pankrantz, Ellen Goode, Janet Olsen, Robert Vierkant, Julie Cunningham, Joellen Shildkraut, Thomas Sellers, and Johnathan Lancaster
Genomic analysis of ovarian cancers can identify single nucleotide polymorphisms associated with ovarian cancer risk
AACR Meeting Abstracts 2007 2007: 42.  

Lori Field, Brad Love, Jennifer Kane, Brenda Deyarmin, Jeffrey Hooke, Rachel Ellsworth, and Craig Shriver
Differential gene expression in normal breast tissue from African American and Caucasian women.
AACR Meeting Abstracts 2007 2007: 43.  

Monica Ter-Minassian, Wei Zhou, Geoffrey Liu, Penny Bradbury, Zhaoxi Wang, Matthew Kulke, and David Christiani
Comparison of Internet tools for SNP selection applied to a molecular epidemiological study of non-small cell lung cancer
AACR Meeting Abstracts 2007 2007: 44.  

Jeffrey Chang, Ru-Fang Yeh, Tarik Tihan, John Wiencke, Joseph Wiemels, Ivan Smirnov, Alexander Pico, Hywel Jones, and Margaret Wrensch
Identifying candidate single nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forests
AACR Meeting Abstracts 2007 2007: 45.  

Francisco De La Vega, Fiona Hyland, Katherine Lazaruk, Kelly Li, Kashif Haque, Meredith Yaeger, and Robert Welch
How well do the HapMap SNPs tag functional variants in 217 drug metabolizing enzyme genes?
AACR Meeting Abstracts 2007 2007: 46.  

Matthew Maurer, Susan Geyer, Sophia Wang, Thomas Habermann, Stephen Ansell, Patricia Hartge, and James Cerhan
An approach for assessing multi-SNP association with survival in a candidate gene setting
AACR Meeting Abstracts 2007 2007: 47.  

Susan Slager and Shannon McDonnell
Evaluation of risk scores using two definitions of "high-risk" allele when combining data from multiple genetic variants for data analysis
AACR Meeting Abstracts 2007 2007: 48.  

Nicola Camp, Theresa Werner, and Lisa Cannon-Albright
The familiality of multiple myeloma in the Utah population database
AACR Meeting Abstracts 2007 2007: 49.  

Giske Ursin, Elizabeth Lillie, Myles Cockburn, Wendy Cozen, Yuri Parisky, Ann Hamilton, Nicholas Schork, Melvin Astrahan, and Thomas Mack
A revised heritability estimate of mammographic density
AACR Meeting Abstracts 2007 2007: 50.  

Xifeng Wu, Jie Lin, H. Grossman, Maosheng Huang, Jian Gu, Carol Etzel, Christopher Amos, Colin Dinney, and Margaret Spitz
Projecting individualized probabilities of developing bladder cancer in Caucasians
AACR Meeting Abstracts 2007 2007: 51.  

Marjolein Hemelt, T LAM, S Ho, G Leung, C Schooling, K Mak, and M Zeegers
The mortality fraction partitioned in a specific and a general component: Smoking as a risk factor for bladder cancer mortality in Hong Kong.
AACR Meeting Abstracts 2007 2007: 52.  

William Grant, Cedric Garland, Sharif Mohr, Edward Gorham, and Frank Garland
Projected impact of vitamin D supplementation on cancer incidence worldwide
AACR Meeting Abstracts 2007 2007: 53.  

John Field, Adrian Cassidy, Jonathan Myles, Triantafillos Liloglou, George Xinarianos, Dawn Smith, Asaf Niaz, Richard Page, and Stephen Duffy
Liverpool Lung Project lung cancer risk prediction model
AACR Meeting Abstracts 2007 2007: 54.  

Chris Bajdik, Zenaida Abanto, John Spinelli, Angela Brooks-Wilson, and Rick Gallagher
Identifying related cancer types based on their incidence among people with multiple cancers
AACR Meeting Abstracts 2007 2007: 55.  

James Brody
The age-specific incidence of human carcinomas is described by a normal distribution.
AACR Meeting Abstracts 2007 2007: 56.  

Paule Marie Carli, Ines Janoray, Denis Caillot, Fabienne Dutrillaux, Francois Girodon, Michel Flesch, Bernardine Favre, Francois Bailly, and Marc Maynadie
Interest of a 25-year old haematological specialized registry in the Côte d’or area in France.
AACR Meeting Abstracts 2007 2007: 57.  

Sohee Han, Daehee Kang, Kyoung-Mu Lee, Sue-Kyung Park, Hyo-Seop Ahn, Hyung-Soo Choi, Hee-Young Shin, Hyung-Jin Kang, Hong-Hoe Koo, Jong-Jin Seo, Ji-Eun Choi, and Yoon-Ok Ahn
Risk factors for childhood leukemia development in a case-control study in Korea
AACR Meeting Abstracts 2007 2007: 58.  

Shambhu Joshi, Shyam BK, and Rajan Bhandari
Risk factors of lung cancer in developing country
AACR Meeting Abstracts 2007 2007: 59.  

Pingping Bao
Cancer incidence among children in Shanghai, China from 2002 to 2004.
AACR Meeting Abstracts 2007 2007: 60.  

Xishan Hao
Research of cancer epidemiology and prevention in Tianjin, China
AACR Meeting Abstracts 2007 2007: 61.  

BiYun Qian, KeXin Chen, and XiShan Hao
Comparison of twenty-year cancer incidences between two large metropolitan cities in north and south China
AACR Meeting Abstracts 2007 2007: 62.  

Kin-Yoke Wong, Sin-Eng Chia, Ponnudurai Kuperan, Khai-Mun Lee, Susan Loong, Benjamin Mow, Siok-Bian Ng, Leonard Tan, Suat-Hoon Tan, Miriam Tao, Gee-Chuan Wong, and Adeline Seow
Malignant lymphomas in an Asian population: characteristics of cases and distribution of histological subtypes in the Singapore lymphoma study
AACR Meeting Abstracts 2007 2007: 63.  

Ivan Herbey, Nataliya Ivankova, and William Grizzle
Cancer development trends in Eastern European countries and the United States: A comparative study
AACR Meeting Abstracts 2007 2007: 64.  

Amy Linabery and Julie Ross
Pediatric cancer incidence and survival in the United States (1973-2003)
AACR Meeting Abstracts 2007 2007: 65.  

Thomas Nishino, Raleigh Johnson, Tuenchit Khamapirad, Donald Brunder, James Grady, and Lee Jane Lu
Non-contrast magnetic resonance imaging (MRI) for measuring fibroglandular tissue volume of the breast
AACR Meeting Abstracts 2007 2007: 66.  

Regulators of apoptosis: Poster Presentations - Late-Breaking Abstracts:Back

So-Young Kim and Yong-Sung Juhnn
Stimulatory heterotrimeric GTP-binding protein inhibits gamma ray-induced apoptosis in SH-SY5Y human neuroblastoma cells
AACR Meeting Abstracts 2007 2007: LB-39.  

Sam Thiagalingam, Jose Ponte, Panagiotis Papageorgis, Hamid Abdolmaleky, and Fangming Gao
hBub1 is a suppressor of apoptosis during mitotic spindle damage
AACR Meeting Abstracts 2007 2007: LB-40.  

Yong Fu, Jianze Li, and Amy Lee
The Unfolded Protein Response Regulator GRP78 as a Novel Target for Increasing Sensitivity of Human Breast Cancer Cells to Antiestrogen Therapy
AACR Meeting Abstracts 2007 2007: LB-41.  

Alex Almasan, Suparna Mazumder, and Dragos Plesca
Proteasome-inhibitor triggered cell death in hematopoietic cells is dependent on the interaction of a Cyclin E1 Fragment with Ku70 to regulate Bax-mediated apoptosis
AACR Meeting Abstracts 2007 2007: LB-42.  

Ronald Fiscus, Madhavi Bathina, Mary Johlfs, Sunil Sharma, and Nicholas Vogelzang
ODQ, an inhibitor of soluble guanylyl cyclase (nitric oxide-activated enzyme), enhances the pro-apoptotic effects of cisplatin in human mesothelioma cells
AACR Meeting Abstracts 2007 2007: LB-43.  

Xiuyun Ding, Andrew Buermeyer, Zhiqing Huang, Herbert Lyerly, Andrew Berchuck, Susan Murphy, and Gayathri Devi
Novel role of mismatch repair protein MLH-1 as an apoptotic sensor in cisplatin sensitivity in ovarian Cancer
AACR Meeting Abstracts 2007 2007: LB-44.  

Enhancement of apoptosis by chemotherapeutic agents: Poster Presentations - Late-Breaking Abstracts:Back

Liao Hui-Fen and Yu-Jen Chen
Norcantharidin, a derivative compound from blister beetles, induces anoikis-mediated apoptosis in CT26 colorectal adenocarcinoma cells
AACR Meeting Abstracts 2007 2007: LB-45.  

Yoonmi Lee, Hyang Tae Choi, Hyeonseok Ko, and Kunhong Kim
Anti-cancer drugs mediated PKCK2 activity downregulation sensitize TRAIL-resistant cancer cells toward TRAIL
AACR Meeting Abstracts 2007 2007: LB-46.  

Michela Carlet, Stefan Schmidt, Kristina Janjetovic, Susanne Lobenwein, Christian Ploner, and Reinhard Kofler
PFKFB2 gene in GC-induced apoptosis
AACR Meeting Abstracts 2007 2007: LB-47.  

Molecular marker studies: Poster Presentations - Late-Breaking Abstracts:Back

William Cho
Molecular biomarker discovery and progress in nasopharyngeal carcinoma
AACR Meeting Abstracts 2007 2007: LB-49.  

Lisa Wenrich, Mark Landers, Xiquan Liang, Brad Love, Marshall Pope, and Christopher Adams
Validating microRNA targeting of downregulated breast cancer biomarkers
AACR Meeting Abstracts 2007 2007: LB-50.  

Lixin Yang, Xiwei Wu, Yun Yen, and Ren-Jang Lin
Use whole genome tiling microarray to evaluate Her2/NEU status of breast cancer
AACR Meeting Abstracts 2007 2007: LB-51.  

Functional identification of new cancer genes: Poster Presentations - Late-Breaking Abstracts:Back

Yu-Chung Wu, Chang-Han Chen, Chi-Ying Huang, Li-Jen Su, and Jacqueline Whang-Peng
Identification of Therapeutic Targets for Lung Adenocarcinoma by Functional Genomics
AACR Meeting Abstracts 2007 2007: LB-52.  

Cloning of cancer genes: Poster Presentations - Late-Breaking Abstracts:Back

Judith Clements, Aneel Kaushal, Stephen Myers, Ying Dong, Olivia Tan, Loan Bui, John Lai, Matthew Digby, Hemamali Samaratunga, Robert Gardiner, and John Hooper
The novel gene, KRIP 1, which is androgen regulated and down-regulated in prostate cancer, encodes the first non-serine protease identified from the human PSA/kallikrein-related (KLK) gene locus.
AACR Meeting Abstracts 2007 2007: LB-53.  

Akira Watanabe, Yuichi Torisu, Aya Nonaka, Yutaka Midorikawa, Takahiro Shimamura, Hiroko Iwanari, Atsushi Niida, Tetsu Akiyama, Tatsuhiko Kodama, Masatoshi Makuuchi, Mikio Zeniya, and Hiroyuki Aburatani
A human homolog of Notum, overexpressed in hepatocellular carcinoma, is transcriptionally regulated by beta-catenin/TCF
AACR Meeting Abstracts 2007 2007: LB-54.  

Molecular cytogenetics: Poster Presentations - Late-Breaking Abstracts:Back

Prasad Dhulipala, Greg Kaput, Wendell Fortson, and Shyam Reddy
Identification of chromosomal abnormalities in prostate cancer by array CGH
AACR Meeting Abstracts 2007 2007: LB-55.  

Epigenetic detection methods: Poster Presentations - Late-Breaking Abstracts:Back

Catherine Foo, David Gordon, Svetlana Shchegrova, Shane Giles, Eric LeProust, Stephen Milligan, Chris Hopkins, Arindam Bhattacharjee, Rini Mukherjee Saxena, and Doug Roberts
A High Resolution Oligonucleotide CpG Island Microarray
AACR Meeting Abstracts 2007 2007: LB-56.  

Growth factors and cell surface-related oncogenes and tumor suppressor genes : Poster Presentations - Late-Breaking Abstracts:Back

Won-Jing Wang, Wei Kuo, Jean-Cheng Kuo, Feng-Chi Lin, Pei-Rung Wu, and Ruey-Hwa Chen
The tumor suppressor DAPK is reciprocally regulated by tyrosine kinase Src and phosphatase LAR
AACR Meeting Abstracts 2007 2007: LB-57.  

PENG LI, Stephanie Schulz, Alessandro Bombonati, Juan Palazzo, Terry Hyslop, Yihuan Xu, Amy Baran, Linda Siracusa, Giovanni Pitari, and Scott Waldman
Guanylyl Cyclase C Suppresses Intestinal Tumorigenesis By Restricting Proliferation And Maintaining Genomic Integrity
AACR Meeting Abstracts 2007 2007: LB-58.  

JAYOUNG KIM, Wan Jin Jahng, Dolores Vizio, Julie Lee, Mark Rubin, Assia Shisheva, and Michael Freeman
Trafficking and regulatory mechanisms of EGFR transcriptional function in bladder cancer
AACR Meeting Abstracts 2007 2007: LB-59.  

Carol Lee, ST Fan, WH Sit, Irene WY Jor, Leo LY Wong, K Man, KC Tan-Un, and Jennifer MF Wan
Olive oil enriched diet suppresses hepatocellular carcinoma (HCC) tumor growth via focal adhesion pathway
AACR Meeting Abstracts 2007 2007: LB-60.  

Daniel Costa, Susumu Kobayashi, Balazs Halmos, Susan Schumer, Mark Huberman, Amit Kumar, Titus Boggon, and Daniel Tenen
Bim mediates EGFR tyrosine kinase inhibitor induced apoptosis in non-small cell lung cancers and is linked to the resistance conferred by secondary EGFR mutations, T790M and the novel L747S
AACR Meeting Abstracts 2007 2007: LB-61.  

Lizheng Guo, Diansheng Zhong, Xiuju Liu, Xue-Yuan Dong, Xiaodong Sun, Paula Vertino, Carlos Moreno, Jing-Tang Dong, and Wei Zhou
Somatic hypermethylation of Sox7 in prostate cancers
AACR Meeting Abstracts 2007 2007: LB-62.  

Yi Zhan and Donald O'Rourke
EGFRvIII oncoprotein induces differential tyrosine phosphorylation and subcellular localization of SHP-2 protein tyrosine phosphatase (PTPase) in GBM cells
AACR Meeting Abstracts 2007 2007: LB-63.  

Pamela Pollock, Michael Gartside, Liza Dejesa, Mathew Powell, Mary Anne Mallon, Helen Davies, Moosa Mohammadi, Andrew Futreal, Michael Stratton, Jeffrey Trent, and Paul Goodfellow
Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes
AACR Meeting Abstracts 2007 2007: LB-64.  

Cytoplasmic signal transducers : Poster Presentations - Late-Breaking Abstracts:Back

Motoko Niida, Keiji Wada, and Tetsu Kamitani
Deubiquitination of Ro52 by an oncogenic protein UnpEL
AACR Meeting Abstracts 2007 2007: LB-65.  

Sarasija Hoare, Kishalay Hoare, Mary Reinhard, and W. Stratford May
Aberrant Ras signaling in Kos1 knockout mice leads to spontaneous tumor development
AACR Meeting Abstracts 2007 2007: LB-66.  

Martina Lutterova, Gabor Mehes, Christian Gully, Kurt Zatloukal, and Marcus Otte
Changes in the expression pattern of Rheb 2, a direct activator of mTOR, in primary human liver cancer
AACR Meeting Abstracts 2007 2007: LB-67.  

Occupation, Smoking, Other Exposures, and Cancer Risk: Poster Presentations:Back

Kofi Asomaning, David Miller, Geoffrey Liu, John Wain, Thomas Lynch, Li Su, and David Christiani
Second hand smoke, age of exposure and lung cancer risk
AACR Meeting Abstracts 2007 2007: 67.  

Jian-Min Yuan, Woon-Puay Koh, Renwei Wang, Hin-Peng Lee, and Mimi Yu
High susceptibility of lean smokers to lung cancer: findings from the Singapore Chinese health study
AACR Meeting Abstracts 2007 2007: 68.  

John Neuberger
Residential radon exposure and lung cancer
AACR Meeting Abstracts 2007 2007: 69.  

Li Liu, jia Su, Lina Mu, Zuofeng Zhang, Baoxin Zhao, Jianping Shi, and Yanping Zhang
Smoking, indoor air pollution and risk of lung cancer in a Chinese population
AACR Meeting Abstracts 2007 2007: 70.  

Ramanakumar Agnihotram, Marie-Elise Parent, and Jack Siemiatycki
Exposure to titanium dioxide, carbon black and cosmetic talc and risk of lung cancer: results from two case-control studies in Montreal
AACR Meeting Abstracts 2007 2007: 71.  

Assieh Melikian, Mirjana Djordjevic, John Richie, and Steven Stellman
Differences in smoking behavior and toxin exposure in smokers of low- and high-yield cigarettes
AACR Meeting Abstracts 2007 2007: 72.  

Qing Lan, Xingzhou He, Min Shen, Larry Liu, Hong Lai, Wei Chen, Aaron Blair, Linwei Tian, and Robert Chapman
Spatial variation in lung cancer risk associated with smoky coal use in Xuanwei, China
AACR Meeting Abstracts 2007 2007: 73.  

Arora Shitij and Jayant Sharma
An epidemiological profile of oral and oropharyngeal lesions in tobacco smokers and chewers of central India
AACR Meeting Abstracts 2007 2007: 74.  

Ying-Ying Yu, Neil Caporaso, Paul Pinsky, Nilanjan Chatterjee, and Eric Engels
Lung cancer risk after detection of granulomas or scarring on chest radiograph
AACR Meeting Abstracts 2007 2007: 75.  

Francesco Barone-Adesi, Daniela Ferrante, Marinella Bertolotti, Annalisa Todesco, Dario Mirabelli, Benedetto Terracini, and Corrado Magnani
Mortality for pleural and peritoneal cancer after a long time since first exposure to asbestos: evaluation of the possible role of asbestos clearance
AACR Meeting Abstracts 2007 2007: 76.  

Jeppe Friborg, Jian-Min Yuan, Renwei Wang, Woon-Puay Koh, Hin-Peng Lee, and Mimi Yu
Incense use and respiratory tract carcinomas: a prospective cohort study
AACR Meeting Abstracts 2007 2007: 77.  

Ted Brasky, Matthew Bonner, Saxon Graham, John Vena, James Marshall, Joan Dorn, John Brasure, and Jo Freudenheim
Tonsillectomy and breast cancer risk in the WNY Diet Study
AACR Meeting Abstracts 2007 2007: 78.  

Wei Wang, Jie Lin, Ashish Kamat, Maosheng Huang, and Xifeng Wu
The risk for bladder cancer in relation to multiple occupational exposures
AACR Meeting Abstracts 2007 2007: 79.  

Inger Gram, Tonje Braaten, Eiliv Lund, and Elisabete Weiderpass
Cigarette smoking and the incidence of colorectal cancer
AACR Meeting Abstracts 2007 2007: 80.  

Perrotta Carla, Staines Anthony, Silke Kleefeld, Dominique Crowley, Paolo Boffetta, Mark Lawler, Lenka Foretova, Silvia San Jose, Alan Nieter, M Maynadie, and Pierluggi Cocco
Multiple myeloma and occupation: Results from the Epilymph study
AACR Meeting Abstracts 2007 2007: 81.  

Jeppe Friborg, Jian-Min Yuan, Renwei Wang, Woon-Puay Koh, Hin-Peng Lee, and Mimi Yu
A prospective study of tobacco and alcohol use as risk factors for pharyngeal carcinomas in Singapore Chinese
AACR Meeting Abstracts 2007 2007: 82.  

Kimberly Johnson, Bruce Alexander, Logan Spector, Michele Doody, Alice Sigurdson, Martha Linet, and Julie Ross
The association between working during pregnancy and childhood cancer in the offspring of radiologic technologists
AACR Meeting Abstracts 2007 2007: 83.  

Josh Marehbian, Joanne Colt, Dalsu Baris, Patricia Stewart, Therese Stukel, Steven Spencer, and Margaret Karagas
Occupation and keratinocyte cancer risk: a population-based case control study
AACR Meeting Abstracts 2007 2007: 84.  

Robert Dyer, Martin Weinstock, and VATTC Trial Group
Predictors of basal cell carcinoma in a high risk population
AACR Meeting Abstracts 2007 2007: 85.  

Frank Meyskens, Sun Yang, Dwight Culver, Hoda Anton-culver, and Patrick Farmer
Involvement of heavy metal ions in the pathogenesis of cutaneous melanoma: experimental and epidemiologic evidence
AACR Meeting Abstracts 2007 2007: 86.  

Yuan-Chin Lee, Catherine Cohet, Yu-Ching Yang, Mia Hashibe, and Kurt Straif
Meta-analysis of 94 epidemiologic studies on cigarette smoking and liver cancer
AACR Meeting Abstracts 2007 2007: 87.  

Isabelle Stucker, Jean Francois Ferrand, Sylvie Cenee, Denis Hemon, Philippe Beaune, Pierre Laurent-Puig, Marie-Anne Loriot, Jean Pierre Bronowicki, Francoise Degos, Jean Claude Trinchet, and Gilles Pelletier
Occupational risk factors and hepatocellular carcinoma: A french case control study.
AACR Meeting Abstracts 2007 2007: 88.  

Jianying Han, Zhixiang Xu, Jiaju Tan, and Haiping Xing
Relationship between incidence and mortality of esophageal Ccancer and improvement of drinking water
AACR Meeting Abstracts 2007 2007: 89.  

Akio Hiraki, Keitaro Matsuo, Takeshi Suzuki, and Kazuo Tajima
Tooth loss and the risk of cancer: a cross-sectional study based on hospital-based epidemiologic research program at Aichi Cancer Center (HERPACC)
AACR Meeting Abstracts 2007 2007: 90.  

Melissa Rotunno, Angela Pesatori, Andrew Bergen, Peggy Tucker, Sholom Wacholder, Alisa Goldstein, Jay Lubin, Lynn Goldin, Michael Alavanja, Amy Subar, Glen Morgan, Dario Consonni, PierAlberto Bertazzi, Neil Caporaso, and Maria Teresa Landi
Environment And Genetics in Lung cancer Etiology (EAGLE): A novel population-based case-control study of lung cancer.
AACR Meeting Abstracts 2007 2007: 91.  

zhixiang Xu and Jianying Han
Experiment of Cancer Induction by Feeding Farm Compost Water
AACR Meeting Abstracts 2007 2007: 92.  

Adrian Cassidy, Kella Hodaj, Christian Brambilla, Yves Martinet, Erik Thunnissen, Peter Snijders, Gabriella Sozzi, Angela Risch, Stuart Elborn, Luis Montuenga, Ken O'Byrne, David Harrison, Jacek Niklinski, and John Field
The European Early Lung Cancer project (EUELC): a multicentred case-control study of lung cancer in Europe
AACR Meeting Abstracts 2007 2007: 93.  

Sharon Glynn, Brenda Boersma, Tiffany Howe, Harris Yfantis, and Stefan Ambs
NOS2 expression in estrogen receptor-negative breast cancer predicts survival.
AACR Meeting Abstracts 2007 2007: 94.  

Carol Sweeney, Kathy Baumgartner, Anna Giuliano, Tim Byers, Jennifer Herrick, and Martha Slattery
Reproductive history in relation to breast cancer risk among Hispanic and white, non-Hispanic women; the 4 Corners Study
AACR Meeting Abstracts 2007 2007: 95.  

Susan Puumala, Julie Ross, Andrew Olshan, Leslie Robison, Franklin Smith, and Logan Spector
Reproductive history, infertility treatment, and the risk of acute leukemia in children with Down Syndrome: A report from the Children’s Oncology Group (COG)
AACR Meeting Abstracts 2007 2007: 96.  

Nuclear oncoproteins and tumor suppressor genes: Poster Presentations - Late-Breaking Abstracts:Back

Jia-Rong Fan, Mei-Yi Hsieh, Han-Wen Chang, Hsiang-Chin Chen, Tang-Long Shen, Shu-Chun Teng, Leroy F. Liu, and Tsai-Kun Li
A novel role of topoisomerase III in cell cycle checkpoint and tumorigenesis
AACR Meeting Abstracts 2007 2007: LB-68.  

Ryuichi Fukuyama, Kwok Peng Ng, and Nywana Sizemore
MCC (mutated in colorectal cancer) acts in divergent roles as a potential tumor suppressor and promoter
AACR Meeting Abstracts 2007 2007: LB-69.  

Peng Guo, Xue-yuan Dong, Kewen Zhao, and Jin-tang Dong
KLF5 is an essential regulator of ER activity in breast cancer
AACR Meeting Abstracts 2007 2007: LB-70.  

Jun Wei, Adam Tai Chi Cheuk, Young Song, Qingrong Chen, Steffen Durinck, Li-Rong Yu, Timothy Veenstra, and Javed Khan
miR-34a is a potential tumor suppressor gene on 1p36 in neuroblastoma
AACR Meeting Abstracts 2007 2007: LB-71.  

Mouse models of human cancer: Poster Presentations - Late-Breaking Abstracts:Back

Arusha Oloumi, Howard Tearle, Mykola Maydan, Julia Mills, Nasrin Mawji, and Shoukat Dedhar
Mammary specific expression of integrin linked kinase results in accelerated tumorgenesis in MMTV-Wnt-1 transgenic mice
AACR Meeting Abstracts 2007 2007: LB-75.  

Raju Pusapati, Qiwei Paulson, Robert Rounbehler, Mark McArthur, and David Johnson
Oncogenes induce DNA damage in vivo leading to the activation of the ATM DNA damage response pathway
AACR Meeting Abstracts 2007 2007: LB-77.  

Richard Finnell, Barton Kamen, Evelyn Callaway, Laurie Davidson, and Robert Chapkin
Use of novel genetic mouse models to investigate the health benefits of folate in colon cancer
AACR Meeting Abstracts 2007 2007: LB-78.  

Matt Grimmer, Selma Masic, Rodney Collins, Mai Nagaoka, Kohichi Tanaka, Tarik Tihan, C. James, William Weiss, and Louis Chesler
Targeted expression of MYCN causes medulloblastoma in mice
AACR Meeting Abstracts 2007 2007: LB-79.  

Kamel Izeradjene, Chelsea Combs, Melissa Best, Aarthi Gopinathan, Amary Wagner, William Grady, Chu-Xia Deng, Ralph Hruban, Volkan Adsay, David Tuveson, and Sunil Hingorani
Oncogenic KrasG12D and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas
AACR Meeting Abstracts 2007 2007: LB-80.  

Human-in-mouse models of human cancer: Poster Presentations - Late-Breaking Abstracts:Back

Marco De Velasco, Motoyoshi Tanaka, Satoshi Anai, Atsushi Tomioka, Sayaka Yoshiba, Kazuto Nishio, and Hirotsugu Uemura
Improved mouse orthotopic bladder cancer model quantification using GFP image analysis
AACR Meeting Abstracts 2007 2007: LB-81.  

3-D and tissue recombinant models: Poster Presentations - Late-Breaking Abstracts:Back

Sophie Richon, Louis-Bastien Weiswald, Marianne Briffod, Bruno Saubamea, Rene Lai-Kuen, Alain Pecking, Dominique Bellet, and Virginie Dangles-Marie
Generation and characterization of colospheres, a novel three-dimensional model of human colon cancer cells
AACR Meeting Abstracts 2007 2007: LB-82.  

Other animal and cell models of cancer: Poster Presentations - Late-Breaking Abstracts:Back

AnneMarie Culazzo and Fangxian Sun
Optimal cell density plays a critical role in the hollow fiber assay
AACR Meeting Abstracts 2007 2007: LB-83.  

Non-invasive imaging in animal models: Poster Presentations - Late-Breaking Abstracts:Back

Steven Smith, Muhammad Ahsan, Tamara Troy, David West, Ning Zhang, and Peter Lassota
Bioluminescence and dual probe fluorescence imaging of subcutaneous and ortothopic ovarian tumors in SCID Beige mice with spectral resolution of VivoFluor 680 and VivoFluor 750 probes.
AACR Meeting Abstracts 2007 2007: LB-84.  

Ning Zhang, Heng Xu, Min Chen, Muhammad Ahsan, Kshitij Modi, Steven Smith, and Peter Lassota
Applications for Epi- vs. Trans-illumination and spectral unmixing for non-invasive fluorescence imaging of molecular targets in small laboratory animals
AACR Meeting Abstracts 2007 2007: LB-85.  

Zhaoxia Zhang, Michael Weinstein, Douangsone Vadysirisack, Katherine Knostman, Christophe Plass, and Sissy Jhiang
NISLucYFP/wt knock-in mouse model for studying in vivo transcriptional regulation of Na+/I- symporter
AACR Meeting Abstracts 2007 2007: LB-86.  

Developmental phenotypes of cancer genes: Poster Presentations - Late-Breaking Abstracts:Back

Zulfiqar Gulzar, Hanna Romanska, Paul Abel, Sandra Gendler, and El-Nasir Lalani
Cross talk between the MUC1 cytoplasmic tail and the MEK signaling pathway are important in MUC1 induced morphogenesis in MDCK cells.
AACR Meeting Abstracts 2007 2007: LB-87.  

Adult stem cells: Poster Presentations - Late-Breaking Abstracts:Back

Maria Paz, Silvia Garcia, Daniel Rubio, Javier Garcia Castro, and Antonio Bernad
Comprehensive epigenetic characterization of the methylation profile involved in mesenchymal stem cell spontaneous malignant transformation
AACR Meeting Abstracts 2007 2007: LB-88.  

Rebecca Morris, Shulan Li, Heui-Joon Park, Carol Trempus, and George Cotsarelis
Skin tumor formation from hair follicle bulge keratinocytes in Krt1-15CrePR1;R26R mice
AACR Meeting Abstracts 2007 2007: LB-89.  

Embryonic stem cells: Poster Presentations - Late-Breaking Abstracts:Back

Yupo Ma, Jianchang Yang, Li Chai, Taylor Fowles, Mark Tarango, Nicholas Vogelzang, David Ward, and Louis Fink
SALL4 is a novel biomarker for human germ cell tumors and stem cells
AACR Meeting Abstracts 2007 2007: LB-90.  

Cancer stem cells: Poster Presentations - Late-Breaking Abstracts:Back

Jian Wang, Per Sakariassen, Oleg Tsinkalovsky, Heike Immervoll, Stig Boe, Lars Prestegarden, Gro Rosland, Anders Molven, Rolf Bjerkvig, and Per Enger
CD133-negative glioma cells form tumours, while the onset of CD133 expression coincides with angiogenesis and shortened survival
AACR Meeting Abstracts 2007 2007: LB-91.  

Krit Kitisin, Yi Tang, Eugene Volpe, Jonathan Mendelson, Wilma Jogunoori, Cuiling Li, Chuxia Deng, Susette Mueller, Habtom Ressom, Asif Rashid, Anton Sidawy, Stephen Evans, Kirti Shetty, Michael Zasloff, Bibhuti Mishra, E. Premkumar Reddy, Lynt Johnson, and Lopa Mishra
Evidence that Human Hepatocellular Cancer can Arise from Hepatic Stem Cells as a Consequence of Aberrant TGF-β and IL-6 Signaling
AACR Meeting Abstracts 2007 2007: LB-92.  

Gaelle Larderet, Florence Monville, Nathalie Cervera, Julien Wicinski, Francois Bertucci, Daniel Birnbaum, and Emmanuelle Charaffe-Jauffret
Transcriptional profiling of breast tumoral spheres
AACR Meeting Abstracts 2007 2007: LB-93.  

yunfei zhou, Yan Zhou, Li Feng, Seiji Kondo, and Peng Huang
Inhibition of glycolysis: a novel strategy to overcome drug resistance in CD133+ tumor initiating cells under hypoxic microenvironment
AACR Meeting Abstracts 2007 2007: LB-94.  

Developmental pathways in cancer: Poster Presentations - Late-Breaking Abstracts:Back

Tao Sheng, Laura Adhikari, Jing He, Xiaoli Zhang, Robert Whitehead, Piotr Rychahou, Mark Evers, and Jingwu Xie
The role of the hedgehog pathway in metastasis of pancreatic cancer
AACR Meeting Abstracts 2007 2007: LB-95.  

Junhao Mao and Andrew McMahon
Differential susceptibility to pathway activation in postnatal progenitor/stem cells during Hedgehog induced tumorigenesis.
AACR Meeting Abstracts 2007 2007: LB-96.  

Genitourinary and Gastrointestinal Carcinogenesis: Poster Presentations:Back

Shyama Sajankila, Sujata Choudhury, and Rabindra Roy
Regulation of Nth1 and Tsc2 by Cu in experimental liver cancer model
AACR Meeting Abstracts 2007 2007: 97.  

Satoshi Kokura, Tomohisa Takagi, Osamu Handa, Yuji Naito, Norimasa Yoshida, and Toshikazu Yoshikawa
Gene Expression Analysis in the Liver of Mice Administered Carcinogens and Non-carcinogens---For the development of a new carcinogenicity test---
AACR Meeting Abstracts 2007 2007: 98.  

Huynh Hung, Joseph Fargnoli, Soo Khee Chee, Chow Pierce, and Tran Evelyn
BMS-582664, a dual inhibitor of VEGF and FGF signaling, inhibits tumor growth in the xenograft model of hepatocellular carcinoma
AACR Meeting Abstracts 2007 2007: 99.  

Gihan Hosny, Sanaa Hassan, and Hanan Tayel
The in vivo protective effects of silymarin on DMN-induced hepatotoxicity in rats
AACR Meeting Abstracts 2007 2007: 100.  

Igor Pogribny, Tetyana Bagnyukova, Volodymyr Tryndyak, Beverly Montgomery, Levan Muskhelishvili, and Frederick Beland
Early epigenetic dysregulation in rat liver during 2-acetylaminofluorene-induced hepatocarcinogenesis
AACR Meeting Abstracts 2007 2007: 101.  

Keigo Machida, Helene Liu, Jeffery Hwang, Sugantha Govindarajan, Chun-Hsiang Wang, Alexandra Levine, and Michael Lai
The c-Jun mediates HCV hepatocarcinogenesis through STAT3 activation
AACR Meeting Abstracts 2007 2007: 102.  

Anna Grabowska, Jaime Hughes, and Susan Watson
Use of interfering RNA to investigate the role of endogenous gastrin in the survival of gastrointestinal cancer cells
AACR Meeting Abstracts 2007 2007: 103.  

Li Dong Wang, Fang Du, Jian Ying Zhang, Ji Lin Li, Zong Min Fan, Shan Shan Gao, and Xin He
Multiple serum autoantibodies mini-array analysis on the subjects with esophageal precancerous and cancerous lesions from Linzhou, the highest incidence area for esophageal cancer in Henan, northern China
AACR Meeting Abstracts 2007 2007: 104.  

Mi Kim, Ik Chung, Young Park, Boo Shin, Kyung Kim, and Young Jung
uPAR is up-regulated by lysophosphatidic acid in human gastric cancer cells via multiple signaling pathways
AACR Meeting Abstracts 2007 2007: 105.  

Mohammad Rumi, Lynnsie Ruffino, John DiGiovanni, and Kaoru Kiguchi
Nuclear localization of Akt in gallbladder carcinoma from BK5.erbB2 mice
AACR Meeting Abstracts 2007 2007: 106.  

Chao-Nan Qian, Kyle Furge, Jared Knol, Dan Huang, Jindong Chen, Aaron Massie, Philippe Camparo, Eva Comperat, Mathilde Sibony, Annick Vieillefond, Yves Denoux, Vincent Molinie, Bart Williams, and Bin Teh
Activation of the AKT pathway induces transitional cell carcinoma of the renal pelvis: identification in human tumors and confirmation in animal models
AACR Meeting Abstracts 2007 2007: 107.  

Flore Depeint, Nandita Shangari, Rudolf Furrer, Owen Lee, Hajar Derakhshan, Peter O'Brien, and W. Robert Bruce
Thiamin deficiency increases oxidative stress and the spontaneous formation of aberrant crypt foci (ACF) in Fischer 344 rats
AACR Meeting Abstracts 2007 2007: 108.  

Hiromi Bamba, Shinichi Ban, Yoshiya Goto, Shin Arai, Keiko Ishikawa, Yukinori Imai, Akihiko Takeda, Yoshihide Otani, Isamu Koyama, and Michio Shimizu
Difference of cyclooxygenase-2 expression between colorectal traditional adenomas and serrated polyps (hyperplastic polyps and serrated adenomas)
AACR Meeting Abstracts 2007 2007: 109.  

Ruilan Yan, Jun Ma, Xuyu Zu, Moses Adeyanju, Sarah Robbins, and Deliang Cao
Aldose reductase-like-1 protects colon cells against dietary carbonyl lesions
AACR Meeting Abstracts 2007 2007: 110.  

Khosrow Kashfi and Galina Borodulina
Flurbiprofen benzylnitrate (FBN) inhibits the growth of various human cancer cells in vitro and prevents intestinal carcinogenesis in Min (APCMin/+) mice
AACR Meeting Abstracts 2007 2007: 111.  

Nagahide Matsubara, Atsuki Nagao, Takeshi Kambara, Hiromi Sasamoto, and Noriaki Tanaka
BRAF mutation and CpG island methylation in hyperplastic-like polyps: an alternative pathway to colorectal cancer
AACR Meeting Abstracts 2007 2007: 112.  

Tatsuya Kinjo, Masumi Suzui, Takamitsu Morioka, Tatsuya Kaneshiro, Junya Arakaki, Itatru Chiba, Nao Sunagawa, Nanae Morita, Tadashi Nishimaki, and Naoki Yoshimi
Distribution of premalignant lesions and tumors, and β-catenin gene mutations with reduced expression level of Mgmt mRNA in the colon carcinomas induced by Alkylating reagent plus dextran sulfate sodium.
AACR Meeting Abstracts 2007 2007: 113.  

Swati Saxena, Farwa Batool, and Ranjana Bird
Distribution and phenotype of aberrant crypt foci and tumors located in the distal versus proximal colon of Zucker obese rats.
AACR Meeting Abstracts 2007 2007: 114.  

Toshio Fujisawa, Ayako Tomimoto, Hirokazu Takahashi, Kyoko Yonemitsu, and Atsushi Nakajima
Adiponectin prevents colorectal carcinogenesis through suppressing mTOR signaling pathway stimulated by high fat diet
AACR Meeting Abstracts 2007 2007: 115.  

Keisuke Izumi, Akiko Kubo, Makoto Sato, Tetsuyuki Takahashi, Yoshimi Bando, and Hisanori Uehara
Cancer susceptibility in two rat models of spontaneous diabetes
AACR Meeting Abstracts 2007 2007: 116.  

Onyinye Nwagbara, Selina Darling-Reed, Ronald Thomas, Cynthia Harris, and Richard Gragg
The cytotoxic effects of benzo[a]pyrene, benzo[a]pyrene-7,8-dihydrodiol, and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide on hormone-insensitive prostate carcinoma cell line PC3
AACR Meeting Abstracts 2007 2007: 117.  

Moammir Aziz, Herbert Manoharan, Dawn Church, Nancy Dreckschmidt, Weizong Zhong, Terry Oberley, George Wilding, and Ajit Verma
Protein kinase C{epsilon} associates with signal transducers and activators of transcription 3, which is constitutively activated during induction and progression of prostate cancer
AACR Meeting Abstracts 2007 2007: 118.  

Farideh Mehraein-Ghomi, Elyse Lee, Dawn Church, Marie Kegel, Hirak Basu, and George Wilding
Role of JunD in androgen induction of oxidative stress in androgen-dependent human prostate cancer cells and in mouse prostate
AACR Meeting Abstracts 2007 2007: 119.  

Katherine Vega, Nilesh Gaikwad, Elli Rogan, Ercole Cavalieri, and Maarten Bosland
Steroid hormone-induced prostate carcinogenesis in the Noble (NBL) rat: the effects of an aromatase inhibitor and catechol estrogens
AACR Meeting Abstracts 2007 2007: 120.  

Mildred Acevedo-Duncan
Role of atypical protein kinase C-iota in prostate cancer cell cycle, proliferation, and apoptosis
AACR Meeting Abstracts 2007 2007: 121.  

Telih Boyiri, Richard Somiari, Stephen Russell, Cesar Aliaga, and Karam El-Bayoumy
The effect of 2-N-hydroxyamino-1-methyl-6-phenylimidazo [4,5-b]pyridine (NOH-PhIP) and 5{alpha}-dihydrotestosterone (DHT) individually and in combination on proteomic profiles in the rat prostate gland.
AACR Meeting Abstracts 2007 2007: 122.  

Veronica Yao, Diana Harya, Anil Parwani, Christoph Maier, and Dean Bacich
Prostate carcinogenesis in a PSMA transgenic prostate tissue recombinant model
AACR Meeting Abstracts 2007 2007: 123.  

Chengyu Wu and Jiaoti Huang
PI3 kinase-AKT-mTOR pathway is essential for neuroendocrine differentiation of prostate cancer
AACR Meeting Abstracts 2007 2007: 124.  

Hirak Basu, Rachel Orleck-Lubka, Kathleen Schell, and George Wilding
Time-dependent changes in subcellular localization of reactive oxygen species in androgen-treated LNcap human prostate cancer cells
AACR Meeting Abstracts 2007 2007: 125.  

Jinsong Chen, Fred Kadlubar, Armen Aprikian, and Junjian Chen
A new approach for the quantification of mitochondrial DNA damage and repair in prostate cancer cells
AACR Meeting Abstracts 2007 2007: 126.  

Hormonal control: Poster Presentations - Late-Breaking Abstracts:Back

Hannelore Heemers, Kevin Regan, and Donald Tindall
Androgen induction of the androgen receptor co-activator FHL2 : Evidence for a role for serum response factor in prostate cancer
AACR Meeting Abstracts 2007 2007: LB-99.  

Hormone signaling and inhibitors: Poster Presentations - Late-Breaking Abstracts:Back

Mohammad Asim, Hasan Mukhtar, and Aria Baniahmad
Src kinase promotes the growth of therapy resistant prostate cancer cells via regulation of androgen receptor function
AACR Meeting Abstracts 2007 2007: LB-100.  

Balancing Cost and Clinical Benefits of New Anticancer Agents: A Societal Dilemma: Oral Presentations - Invited Abstracts:Back

Alexander Capron
Making cancer a chronic disease: The ethical predicaments of progress?
AACR Meeting Abstracts 2007 2007: SS01-01.  

Susan Desmond-Hellmann
New anti-cancer agents: Ensuring patient access
AACR Meeting Abstracts 2007 2007: SS01-02.  

Deborah Schrag
The impact of cost-effectiveness analyses on US cancer care
AACR Meeting Abstracts 2007 2007: SS01-03.  

Neal Meropol
Why is there so much interest in the cost of cancer care?
AACR Meeting Abstracts 2007 2007: SS01-04.  

Genomic Instability in Development and Cancer: Oral Presentations - Invited Abstracts:Back

Don Cleveland
Boveri revised: Aneuploidy as an oncogene and tumor suppressor
AACR Meeting Abstracts 2007 2007: SY01-01.  

Rocio Sotillo, Eva Hernando, Elena Diaz-Rodriguez, Julie Teruya-Feldstein, Carlos Cordon-Cardo, Scott Lowe, and Robert Benezra
Transient overexpression of the mitotic checkpoint gene Mad2 leads to chromosome instability and tumors in mice
AACR Meeting Abstracts 2007 2007: SY01-02.  

Tenth Annual AACR-Women in Cancer Research-Charlotte Friend Memorial Lecture: Oral Presentations - Invited Abstracts:Back

Janet Butel
Polyomavirus SV40: Insights into viral carcinogenesis
AACR Meeting Abstracts 2007 2007: LE01-01.  

Translating a Century of Science into a Future of Cancer Prevention and Cures: Oral Presentations - Invited Abstracts:Back

Francis Collins
Cancer: A Disease of the Genome
AACR Meeting Abstracts 2007 2007: PL01-01.  

Elaine Fuchs
Stem cells, morphogenesis, and cancer
AACR Meeting Abstracts 2007 2007: PL01-02.  

Nuclear receptors: structure and function: Poster Presentations - Late-Breaking Abstracts:Back

Angie L. Bookout, Jianjun Chang, John Minna, David Mangelsdorf, and Elisabeth Martinez
Quantitative RT-PCR profiling of the nuclear receptor superfamily across fifty human cancer cell lines derived from nine different tissues
AACR Meeting Abstracts 2007 2007: LB-101.  

Steroid hormone receptors: Poster Presentations - Late-Breaking Abstracts:Back

Patrick Muller, Chin-Yo Lin, Jan-Ake Gustafsson, and Anders Strom
Distal regulation of HES-1 by RAR and ER
AACR Meeting Abstracts 2007 2007: LB-102.  

Irina Agoulnik, Manjula Nakka, and Nancy Weigel
Target gene specific regulation of androgen receptor activity by coactivators and the p42/p44 MAPK pathway.
AACR Meeting Abstracts 2007 2007: LB-103.  

Irina Budunova, Vera Kobzeva, and Alexander Yemelyanov
Role of IKKi in prostate cancer: A link between inflammation and androgen receptor signaling
AACR Meeting Abstracts 2007 2007: LB-104.  

Animal and in vitro models for carcinogenesis: Poster Presentations - Late-Breaking Abstracts:Back

Kadoaki Ohashi, Kannmei Rai, Katsuyuki Kiura, Masahiro Osawa, Seiki Hirano, Yoshiro Fujiwara, Tadashi Yoshino, Nagio Takigawa, Minoru Takata, and Mitsune Tanimoto
Transgenic mice with mouse EGFR mutation developed lung adenocarcinoma
AACR Meeting Abstracts 2007 2007: LB-106.  

Rami Aqeilan, Louise Fong, Nicola Zanesi, Stefan Costinean, Yuri Pekarsky, Sadiq Hussain, Jane Lian, Gary Stein, and Carlo Croce
Role of the WWOX fragile gene in cancer
AACR Meeting Abstracts 2007 2007: LB-107.  

Molecular carcinogenesis: Poster Presentations - Late-Breaking Abstracts:Back

Penny Nymark, Salla Ruosaari, Eeva Kettunen, Harriet Wikman, Eeva Kuosma, Esa Vanhala, Antti Karjalainen, Sakari Knuutila, and Sisko Anttila
Frequent copy number changes on chromosome 9q in asbestos-associated lung cancer
AACR Meeting Abstracts 2007 2007: LB-108.  

Chemical carcinogenesis: Poster Presentations - Late-Breaking Abstracts:Back

Masashi Izumiya, Masako Ochiai, Takashi Sugimura, and Hitoshi Nakagama
Genome-wide Array CGH Analysis Revealed Possibble Microdeletions in Inflammation-associated Colon Tumors in Mice
AACR Meeting Abstracts 2007 2007: LB-109.  

Elise Saunier and Rosemary Akhurst
In vivo inhibition of TGFβ receptor by small molecule inhibitors in mouse cancer models
AACR Meeting Abstracts 2007 2007: LB-110.  

Environmental carcinogenesis: Poster Presentations - Late-Breaking Abstracts:Back

Timothy Whitsett, Vivek Kalia, Isam Eltoum, and Coral Lamartiniere
Prenatal TCDD exposure may predispose the murine uterus to cancer by delaying maturation and altering cell proliferation and apoptosis
AACR Meeting Abstracts 2007 2007: LB-111.  

Host-virus interactions: Poster Presentations - Late-Breaking Abstracts:Back

Camille Ragin, Scott Langevin, Susanne Gollin, Raja Seethala, and Emanuela Taioli
Association of GSTM1 and HPV16 with tumor recurrence in head and neck cancer
AACR Meeting Abstracts 2007 2007: LB-112.  

Predictive assays for carcinogenicity: Poster Presentations - Late-Breaking Abstracts:Back

Vishal Shah, Gang Liu, Paul Oeth, Loren Hansen, Dirk van den Boom, Juri Jurinke, Jerome Brody, and Avrum Spira
Validation of a gene expression based lung cancer biomarker using high-throughput mass spectroscopy technology
AACR Meeting Abstracts 2007 2007: LB-113.  

Premalignant lesions: Poster Presentations - Late-Breaking Abstracts:Back

Aneta Kular and Ranjana Bird
Supplementary vitamin B6 suppresses colon carcinogenesis in Zucker obese rats
AACR Meeting Abstracts 2007 2007: LB-114.  

Reactive oxygen studies/oxidative stress: Poster Presentations - Late-Breaking Abstracts:Back

Weiqin Lu, Helene Pelicano, zhao chen, li feng, and Peng Huang
Mitochondrial respiratory defects lead to significant alterations in cellular redox states and drug sensitivity
AACR Meeting Abstracts 2007 2007: LB-115.  

Cancer in minority and medically underserved populations: Poster Presentations - Late-Breaking Abstracts:Back

Monawar Hosain, Maureen Sanderson, Xianglin Du, Wenyaw Chan, and Sara Strom
Racial/Ethnic differences in prostate cancer xcreening between Caucasians and Hispanics
AACR Meeting Abstracts 2007 2007: LB-117.  

Diet, alcohol, smoking, and other lifestyle risk factors: Poster Presentations - Late-Breaking Abstracts:Back

Chisato Nagata, Yukari Sahashi, Hiroyuki Shimizu, Shinichi Iwasa, and Makoto Shiraki
Association of maternal fat and alcohol intake with maternal and umbilical hormone levels and birth weight
AACR Meeting Abstracts 2007 2007: LB-118.  

Margaret Wright, Yikyung Park, Amy Subar, Neal Freedman, Demetrius Albanes, Traci Mouw, Albert Hollenbeck, Michael Leitzmann, and Arthur Schatzkin
Fruit and vegetable consumption and lung cancer risk in a large cohort of Americans: the NIH-AARP Diet and Health Study
AACR Meeting Abstracts 2007 2007: LB-119.  

Archana McEligot
VEGETABLE, FRUIT, FIBER, FAT AND FOLATE INTAKES, AND BMI IN WOMEN AT HIGH-RISK FOR BREAST AND OVARIAN CANCER.
AACR Meeting Abstracts 2007 2007: LB-120.  

Li Jiao, Debra Silverman, Catherine Schairer, Albert Hollenbeck, Michael Leitzmann, Arthur Schatzkin, and Rachael Stolzenberg-Solomon
Alcohol use, smoking habits, and pancreatic cancer in the NIH-AARP cohort
AACR Meeting Abstracts 2007 2007: LB-121.  

Infections and the etiology of cancer: Poster Presentations - Late-Breaking Abstracts:Back

Angela Watt, Camille Ragin, Novie Younger, David Garwood, Maria Jackson, Monica Smikle, Horace Fletcher, and Norma McFarlane-Anderson
High-risk human papillomavirus (HPV) genotypes in Jamaican women
AACR Meeting Abstracts 2007 2007: LB-122.  

Methodology, modeling, and biostatistics: Poster Presentations - Late-Breaking Abstracts:Back

Carol Etzel, Waun Ki Hong, Sanjay Shete, Qiong Dong, Xifeng Wu, Qingyi Wei, Chris Amos, and Margaret Spitz
An extended lung cancer risk prediction model
AACR Meeting Abstracts 2007 2007: LB-123.  

Prognostic Value of Chromosomal and DNA-based Alterations: Poster Presentations:Back

Jian Gu, H. Grossman, Colin Dinney, and Xifeng Wu
Benzo[a]pyrene diol epoxide-induced 9p21 aberrations and genetic predisposition to bladder cancer
AACR Meeting Abstracts 2007 2007: 127.  

Walter Berger, Sabine Spiegl-Kreinecker, Christine Pirker, Christine Marosi, Johanna Buchroithner, Johannes Fischer, Josef Pichler, Rene Silye, and Michael Micksche
Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma
AACR Meeting Abstracts 2007 2007: 128.  

Ernst-Jan Speel, V. Ewa Bergshoeff, Annick Haesevoets, Fredrik Bot, Adri Voogd, Anton Hopman, Frans Ramaekers, and Johannes Manni
Chromosome instability as detected by FISH predicts progression of premalignant lesions of the larynx
AACR Meeting Abstracts 2007 2007: 129.  

Christine Steudel, Sofia Traikof, Uta Oelschlagel, Wolfram Dempke, Markus Schaich, Gerhard Ehninger, and Christian Thiede
Uniparental disomy in adult acute myeloid leukemia involves specific chromosomes and might be associated with inferior outcome
AACR Meeting Abstracts 2007 2007: 130.  

Andreas Luebke, Bastian Gunnawan, Olaf Hellwinkel, Axel Zander, Hartwig Huland, Andreas Erbersdobler, Laszlo Fuzesi, and Thorsten Schlomm
Analysis of chromosomal aberrations in transition zone cancers of the prostate by comparative genomic hybridization
AACR Meeting Abstracts 2007 2007: 131.  

Kuo-Feng Huang, Ching-Cherng Tzeng, Chiou-Ping Liou, Wen-Yin Lee, Soon-Cen Huang, Yue-Shan Lin, and Chieh-Yi Kang
Chromosomal gain of 3q and loss of 11q are often associated with nodal metastasis in cervical squamous cell carcinoma
AACR Meeting Abstracts 2007 2007: 132.  

Ajay Goel, Jennifer Spiegel, Takeshi Nagasaka, Sung-Kwan Shin, Sheryl Livingston, Richard Meyer, Warren Lichliter, and C. Richard Boland
Frequent loss of hPMS2 and hMSH6 expression in non-familial (sporadic) young patients with colorectal cancer
AACR Meeting Abstracts 2007 2007: 133.  

Cindy Postma, Miriam Koopman, Beatriz Carvalho, Tineke Buffart, Paul Eijk, Godefridus Peters, Bauke Ylstra, Han van Krieken, Cornelis Punt, and Gerrit Meijer
DNA copy number profiles of primary colorectal cancers as predictors of response to therapy
AACR Meeting Abstracts 2007 2007: 134.  

Susan Jewell, Beth Blondin, Mona Legator, Kris Jacobson, John Schulz, Teresa Ruffalo, Paul Matushek, Larry Morrison, and Boris Bastian
Identification of markers RREB1, MYB, CCND1 and centromere 6 for the discrimination between melanoma and nevi FFPE skin biopsies using fish
AACR Meeting Abstracts 2007 2007: 135.  

Yuesheng Jin, Ylva Stewenius, David Lindgren, Tord Jonson, Mattias Hoglund, and David Gisselsson
Chromosomal instability in urothelial bladder cancer is multimodal, predicts metastatic death, and indicates susceptibility to telomerase inhibitor treatment
AACR Meeting Abstracts 2007 2007: 136.  

Kofi Asomaning, Amy Reid, Wei Zhou, Rebecca Heist, Li Su, Lawrence Blaszkowsky, Andrew Zhu, David Ryan, David Christiani, and Geoffrey Liu
MMP polymorphisms and progression-free survival in locally advanced and metastatic pancreatic cancer patients.
AACR Meeting Abstracts 2007 2007: 137.  

Thomas Knosel, Karsten Schluns, Manfred Dietel, and Iver Petersen
Chromosomal alterations in lung metastases of colorectal carcinomas: associations with tissue specific tumor dissemination
AACR Meeting Abstracts 2007 2007: 138.  

Cherie-Ann Nathan, Sherry Martin, Nazanin Amirghahari, and Mary Nordberg
FISH analysis of PTEN in HNSCC tumors and tumor-free margins
AACR Meeting Abstracts 2007 2007: 139.  

Robyn Mercer, Natalie Lucas, Dani Zander, Gregory Tsongalis, and William Coleman
Molecular discrimination of multiple primary versus metastatic cancers of the lung and head and neck
AACR Meeting Abstracts 2007 2007: 140.  

Venkat Katkoori, Rahul Goli, Xu Jia, Tom Callens, Ludwine Messiaen, Nirag Jhala, William Grizzle, Sreelatha Meleth, and Upender Manne
Prognostic value of molecular alterations in high grade colorectal adenocarcinomas varies in African-Americans and Caucasians
AACR Meeting Abstracts 2007 2007: 141.  

Rebecca Heist, Wei Zhou, Geoffrey Liu, Kofi Asomaning, Li Su, Donna Neuberg, John Wain, Thomas Lynch, and David Christiani
DNA repair polymorphisms and overall survival in early stage non-small cell lung cancer
AACR Meeting Abstracts 2007 2007: 142.  

Jingfang Gao, Hong Zhang, Gunnar Arbman, and Xiao-Feng Sun
The mutation and expression of hRAD50 in microsatellite stable and microsatellite unstable colorectal cancers
AACR Meeting Abstracts 2007 2007: 143.  

Patrick Schoffski, Federica Grosso, Miquel Taron, Paolo Casali, Raf Sciot, Ian Judson, Michelle Scurr, Jean Yves Blay, Robert Maki, Rodrigo Ruiz, Axel Lecesne, Antonio Nieto, Juan Tercero, Jose Jimeno, and Rafael Rosell
DNA repair functionality as a molecular signature for sensitivity(S)/resistance(R) in sarcoma patients (pts) treated with trabectedin (ET-743, Yondelis®).
AACR Meeting Abstracts 2007 2007: 144.  

Christiane Houde, Jean Dolce, Brian Bundy, Mary Nesline, Warren Davis, Christine Ambrosone, William McLaughlin, Donald Trump, and Lionel Coignet
The presence of the FRA12E/SMRT fragile site in the genome of prostate cancer (CaP) patients is a predictor of metastatic development.
AACR Meeting Abstracts 2007 2007: 145.  

Yohei Horikawa, Xin Lin, Yimin Zhu, Christopher Wood, Pheroze Tamboli, and Xifeng Wu
From risk to survival: chromosome 3p aberrations in renal cell carcinoma
AACR Meeting Abstracts 2007 2007: 146.  

Kelly Gonzalez, Katie Noltner, Carolyn Buzin, Cindy Wen-Fong, Vu Ngyuen, Jennifer Han, Katrina Lowstuter, Jeffrey Weitzel, William Scaringe, and Steve Sommer
Molecular and clinical characterization of patients with putative Li Fraumeni Syndrome sent for p53 molecular diagnostic testing
AACR Meeting Abstracts 2007 2007: 147.  

Xiaobing Liang, Antonio Fojo, and Jing Jie Yu
Wild type p53 regulates Chk2 phosphorylation at Thr-68 in response to cisplatin treatment in human ovarian cancer
AACR Meeting Abstracts 2007 2007: 148.  

Ann Lee, Irene Lim, Tze-Chuen Lee, Jie-Ting Luo, Danny Ong, Puay Hoon Tan, and Peter Ang
Improved susceptibility testing for BRCA1 and BRCA2 mutations by a comprehensive screening strategy
AACR Meeting Abstracts 2007 2007: 149.  

Ana Gomes, Jorge Reis-Filho, Jose Lopes, Maryou Lambros, Albino Martins, Fernando Schmitt, Fernando Pardal, and Rui Reis
Molecular alterations of c-KIT oncogene in gliomas
AACR Meeting Abstracts 2007 2007: 150.  

Sandra Gaston, Andrew Guerra, Heather Conroe, Gerardo Trejo, Joanna Jung, Jihad Hayek, Robert Lenkinski, and Gary Kearney
Heterogeneous expression of TMPRSS2-ERG gene fusions in human prostate cancer: Insights from transcript maps of patient biopsies and radical prostatectomy specimens
AACR Meeting Abstracts 2007 2007: 151.  

Clara Ricci, Francesco Onida, Elisa Fermo, Claudia Miranda, Davide Soligo, Miloslav Beran, and Giorgio Lambertenghi Deliliers
Acquisition of RAS mutations contributes to progression of CMML from the dysplastic to the proliferative variant
AACR Meeting Abstracts 2007 2007: 152.  

Kazuma Ohyashiki, Yasuo Aota, Akihiko Goto, Daigo Akahane, and Junko Ohyashiki
Clinical implication of JAK2V167F-positive chronic myeloproliferative disorders: semi-quantitative Analysis of Mutated allele by sequence-specific primer-single molecule fluorescence detection assay
AACR Meeting Abstracts 2007 2007: 153.  

Amaya Viros, Jane Fridlyand, Juergen Bauer, John Curtin, Daniel Pinkel, and Boris Bastian
Histomorphological signature of mutation status in melanoma
AACR Meeting Abstracts 2007 2007: 154.  

Massimo Libra, Grazia Malaponte, Giovanni Ligresti, Pietro Gangemi, Roberta Siciliano, Salvatore Travali, Maria Mazzarino, Katia Mangano, Ferdinando Nicoletti, Ellis Wong, Linda Steelman, James McCubrey, and Franca Stivala
Activation of MAPK and AKT pathways by BRAF, NRAS and PIK3CA mutations in melanoma
AACR Meeting Abstracts 2007 2007: 155.  

Haruhiko Sugimura, Koji Okudela, Hiroki Mori, Hiroshi Ogawa, Ken Yamada, Hiroshi Niwa, Kiyoko Nagura, Hisaki Igarashi, Kazuya Takamochi, Tomohiro Bunai, Shinji Kageyama, Masaya Suzuki, and Kazuya Shinmura
Significances of PIK3CA alterations in human lung carcinogenesis
AACR Meeting Abstracts 2007 2007: 156.  

Biomarkers of human exposure to carcinogens and DNA damaging agents: Poster Presentations - Late-Breaking Abstracts:Back

Mu Wang, Dawn Fitzpatrick, Jin-Sam You, Kerry Bemis, Jean-Pierre Wery, and James Ludwig
Searching for Potential Biomarkers of Cisplatin Resistance in Human Ovarian Cancer Using a Label-free LC/MS-based Protein Quantification Method
AACR Meeting Abstracts 2007 2007: LB-127.  

Polymorphisms in genes that modify dietary exposures: Poster Presentations - Late-Breaking Abstracts:Back

Asgeir Brevik, Amit Joshi, Roman Corral, Kimberly Siegmund, David Conti, Loic Le Marchand, John Baron, Robert Haile, and Mariana Stern
Polymorphisms in base excision repair genes as colorectal cancer risk factors and modifiers of the effect of meat intake
AACR Meeting Abstracts 2007 2007: LB-128.  

Polymorphisms in carcinogen metabolism and cancer risk: Poster Presentations - Late-Breaking Abstracts:Back

Rihong Zhai, Geoffrey Liu, Wei Zhou, Li Su, Xihong Lin, Kofi Asomaning, John Wain, Thomas Lynch, and David Christiani
VEGF haplotypes, gender, and the risk of non-small cell lung cancer
AACR Meeting Abstracts 2007 2007: LB-129.  

Hans Ketelslegers, Roger Godschalk, Ralph Gottschalk, Ad Knaapen, Frederik Jan Van Schooten, Jos Kleinjans, and Joost Van Delft
The number of at-risk alleles in carcinogen-metabolizing enzymes decreases with age in a healthy population; Survival of the fittest?
AACR Meeting Abstracts 2007 2007: LB-130.  

Polymorphisms in genes related to cell growth, differentiation, metastatic potential, and apoptosis in cancer risk: Poster Presentations - Late-Breaking Abstracts:Back

Issan Tam, Lai Leung, Lap Chung, and Maria Wong
Germline EGFR mutation is uncommon and plays a limited role in predisposition to lung cancer
AACR Meeting Abstracts 2007 2007: LB-131.  

Polymorphisms related to inflammation, immune response, and oxidative damage in cancer risk: Poster Presentations - Late-Breaking Abstracts:Back

Kwang-Pil Ko, Sue Kyung Park, Yeonju Kim, Jin Gwack, Seung-Sik Hwang, Daehee Kang, Hai-Rim Shin, Soung-Hoon Chang, and Keun-Young Yoo
Inflammation-related genetic polymorphisms of IL-1B, IL-8, IL-10 and risk of gastric cancer in Korea
AACR Meeting Abstracts 2007 2007: LB-132.  

Methodology for SNPs detection and data analysis: Poster Presentations - Late-Breaking Abstracts:Back

Anna Gonzalez-Neira, Juan Maria Rosa-Rosa, Ana Osorio, Emilio Gonzalez, Melissa Southey, Olga Sinilnikova, Henry Lynch, Henry Lynch, Rogier Oldenburg, Cristi van Asperen, Nicoline Hoogerbrugge, Guillermo Pita, Peter Devilee, David Goldgar1, and Javier Benitez
Genomewide High-Density SNP Linkage analysis of non-BRCA1/2 breast cancer families identifies various candidate regions and has more power than microsatellite studies
AACR Meeting Abstracts 2007 2007: LB-133.  

Molecular epidemiology of cancer recurrence and survival: Poster Presentations - Late-Breaking Abstracts:Back

Mary Lund, Katrina Trivers, Peggy Porter, Jonathan Liff, Ralph Coates, Elaine Flagg, Otis Brawley, and J Eley
Race and triple negative threats to breast cancer survival
AACR Meeting Abstracts 2007 2007: LB-135.  

Obesity, diet, physical activity, and energy balance: Poster Presentations - Late-Breaking Abstracts:Back

Sara Tamers, Tanya Agurs-Collins, Kevin Dodd, and Linda Nebeling
U.S. and France fruit and vegetable consumption patterns
AACR Meeting Abstracts 2007 2007: LB-138.  

Health economics, policy, and outcomes: Poster Presentations - Late-Breaking Abstracts:Back

Hans-Robert Metelmann, Wolfram Kaduk, Katharina Beier, Hubertus Buchstein, and Steffen Flessa
The impact of cancer politics on oral cancer survival rates
AACR Meeting Abstracts 2007 2007: LB-139.  

Animal models in prevention: Poster Presentations - Late-Breaking Abstracts:Back

Curt Harper, Brijesh Patel, Jun Wang, Isam Eltoum, and Coral Lamartiniere
Characterization of adenocarcinoma in SV-40 Tag transgenic rats as a model to study prostate cancer
AACR Meeting Abstracts 2007 2007: LB-140.  

Andrew Skildum, Olga Zhdankin, Amy Greene, Mingqian Duan, Ronald Regal, and Teresa Rose-Hellekant
Molecular targets of Tamoxifen in a growth factor-active ER+/PR- mouse model of mammary tumorigenesis
AACR Meeting Abstracts 2007 2007: LB-141.  

Biological and biochemical mechanisms in prevention: Poster Presentations - Late-Breaking Abstracts:Back

Yan Shi and Sanjay Srivastava
Triphala, an Ayuervedic Herbal Medicine inhibits in vitro and in vivo growth of pancreatic cancer cells
AACR Meeting Abstracts 2007 2007: LB-142.  

Biomarkers and intervention studies: Poster Presentations - Late-Breaking Abstracts:Back

Michele Carbone, Harvey Pass, Haining Yang, Monica Rdzaneck, Barbara Kroczynska, Murat Tuncer, Y. Izzettin Baris, and Salih Emri
Early detection of mesothelioma in the mesothelioma villages in Turkey
AACR Meeting Abstracts 2007 2007: LB-143.  

William Cho
Potentially useful biomarkers for the diagnosis, treatment and prognosis of lung cancer
AACR Meeting Abstracts 2007 2007: LB-150.  

Randall Holcombe, Anthony Nguyen, Michael Stamos, Christopher Hope, and Kestutis Planutis
Low dose resveratrol-containing grape compound inhibits a panel of Wnt target genes in normal colonic mucosa in vivo: Preliminary results of a phase I dose de-escalation trial with biologic endpoints.
AACR Meeting Abstracts 2007 2007: LB-349.  

Chemoprevention studies: Poster Presentations - Late-Breaking Abstracts:Back

Rong Wang, Wan Mohaiza Dashwood, Christiane Lohr, Kay Fischer, Clifford Pereira, Mandy Louderback, George Bailey, David Williams, and Roderick Dashwood
Effects of white tea, EGCG and caffeine on PhIP-induced tumorigenesis and β-catenin expression
AACR Meeting Abstracts 2007 2007: LB-144.  

Vijay Thakur, ARM Amin, Rajib Paul, and Munna Agarwal
p21-mediated cell cycle arrest predominates and protects colon cancer cells from p53-dependent apoptosis by EGCG
AACR Meeting Abstracts 2007 2007: LB-145.  

Rajib Paul, ARM Amin, Vijay Thakur, and Munna Agarwal
p53-dependent generation of reactive oxygen species mediates apoptosis by luteolin
AACR Meeting Abstracts 2007 2007: LB-146.  

Molecular targets for cancer prevention - development of new agents: Poster Presentations - Late-Breaking Abstracts:Back

Goo Lee, Navdha Mittal, Guang-Yu Yang, Gery Grimm, David Shealy, Linheng Li, and Terrence Barrett
Prevention of Colitis-Induced Cancer by TNF Neutralization in IL-10-Deficient Mice
AACR Meeting Abstracts 2007 2007: LB-147.  

Diet and cancer: Poster Presentations - Late-Breaking Abstracts:Back

Gillian Lindzon, Alan Medline, Kyoung-Jin Sohn, Steven Gallinger, Ruth Croxford, and Young-In Kim
Effect of folic acid supplementation on the progression of colorectal aberrant crypt foci
AACR Meeting Abstracts 2007 2007: LB-148.  

Chantal Barthomeuf, Sylvie Lamy, Richard Beliveau, and Philippe Chollet
Anthocyanin-rich berry extracts and epigallocatechin gallate reduce the enhanced invasiveness of estrogen-negative human breast carcinoma cells elicited by serum
AACR Meeting Abstracts 2007 2007: LB-149.  

Prevention and treatment of premalignant lesions (intraepithelial neoplasia): Poster Presentations - Late-Breaking Abstracts:Back

Lewei Zhang, Catherine Poh, Samson Ng, Michele Williams, Denise Laronde, Calum MacAulay, and Miriam Rosin
Direct fluorescence visualization as adjunct for identification of high-risk oral premalignancies
AACR Meeting Abstracts 2007 2007: LB-151.  

Biomarkers: Poster Presentations - Late-Breaking Abstracts:Back

Hans Nielsen, Nils Brunner, Gerard Davis, Barry Dowell, Robert Doss, Petra Stieber, Rien Blankenstein, Denis King, and Ib Christensen
Plasma TIMP-1 combined with plasma CEA measurements in risk assessment for CRC. A population based, prospective study of 5,005 individuals at risk of CRC.
AACR Meeting Abstracts 2007 2007: LB-153.  

John Russell, Tracey Colpitts, Javier Ramirez, Eric Russell, Bhawani Singh, and Stephen Stroupe
Identification of a peptide autoimmune marker for lung cancer
AACR Meeting Abstracts 2007 2007: LB-154.  

Valerie Sevchenko, Natalia Arnotskaya, Oxana Trifonova, Valentina Yurchenko, and David Zaridze
Human plasma protein markers associated with squamous cell cancer (SCC) of the lung
AACR Meeting Abstracts 2007 2007: LB-155.  

Philip Carpenter, Jessica Wang-Rodriguez, Owen Chan, and Sharon Wilczynski
Laminin 5 Expression in Metaplastic Breast Carcinomas
AACR Meeting Abstracts 2007 2007: LB-156.  

Matthew Nitz, Alex Baras, Steven Smith, and Dan Theodorescu
Discovery of novel urine biomarkers in bladder cancer
AACR Meeting Abstracts 2007 2007: LB-157.  

Shwayta Kukreti, Albert Cerussi, Bruce Tromberg, and Enrico Gratton
Investigation of specific endogenous spectroscopic biomarkers of breast tumors revealed by a new approach to analysis of near-ir spectra
AACR Meeting Abstracts 2007 2007: LB-158.  

Samuel DePrimo, Charles Harmon, Leonard Saltz, Heinz-Josef Lenz, John Marshall, Lee Rosen, Robert Belt, Herbert Hurwitz, S Eckhardt, Emily Bergsland, A Lockhart, Caio Rocha Lima, John Smeraglia, Edna Chow Maneval, and Richard Chao
Variations in circulating levels of VEGF and sVEGFR-2, sVEGFR-3 and sKIT in metastatic CRC patients treated with sunitinib after failure of prior chemotherapy with or without bevacizumab
AACR Meeting Abstracts 2007 2007: LB-361.  

Tumor Proteins in Genitourinary and Other Cancers: Poster Presentations:Back

Kari Rostad, Thorsten Schlomm, Svein Haukaas, Ole Halvorsen, Lars Akslen, Olaf Hellwinkel, and Karl-Henning Kalland
Detection of TMPRSS2:ERG translocations in the urine of prostate cancer patients
AACR Meeting Abstracts 2007 2007: 157.  

Viju Ananthanarayanan, Ryan Deaton, Ed Luther, Vicki Macias, Andre Balla, and Peter Gann
Automated digital analysis of tissue microarrays with brightfield and laser-based systems: application to subcellular localization of p27 and prostate cancer recurrence
AACR Meeting Abstracts 2007 2007: 158.  

A Toubaji, G Netto, K Lecksell, J Hicks, and A De Marzo
Prognostic significance of MCM2 expression in prostate carcinoma
AACR Meeting Abstracts 2007 2007: 159.  

Thorsten Schlomm, Anna Petersen, Olaf Hellwinkel, Andreas Lubke, Markus Graefen, Andreas Erbersdobler, Hans Heinzer, Hartwig Huland, Guido Sauter, and Ronald Simon
Alterations of the physiological PSMA expression patterns are associated with poor prognosis in prostate cancer
AACR Meeting Abstracts 2007 2007: 160.  

Arnold Schwartz, Yan-Gao Man, Katayoon Rezaei, and Patricia Berg
BP1, a homeoprotein, is significantly expressed in prostatic adenocarcinoma and concordant with prostatic intraepithelial neoplasia
AACR Meeting Abstracts 2007 2007: 162.  

Roble Bedolla, Jeffrey Kreisberg, Shazli Malik, Thomas Prihoda, Naveen Krishnegowda, Dean Troyer, and Paramita Ghosh
Prognostic potential of PTEN expression and Akt activation in determining risk of biochemical recurrence in prostate cancer
AACR Meeting Abstracts 2007 2007: 163.  

Jonathon Staples, Kristie Aamodt, Byron Murray, and Kim O'neill
Identifying different stages of prostate cancer using thymidine kinase 1
AACR Meeting Abstracts 2007 2007: 164.  

Preusser Matthias, Adelheid Woehrer, Oskar Koperek, Andrea Rottenfusser, Karin Dieckmann, Brigitte Gatterbauer, Karl Roessler, Irene Slavc, Berthold Streubel, Johannes Hainfellner, and Andreas Chott
Primary central nervous system lymphomas: a surprisingly homogenous activated B-cell lymphoma category
AACR Meeting Abstracts 2007 2007: 165.  

Joseph Stuckert, Ahmad Tarhini, Sandra Lee, Cindy Sander, James Schlesselman, Yun Wang, Helen Gogas, and John Kirkwood
Interferon alfa-induced autoimmunity in patients with high-risk melanoma participating in ECOG phase II trial E2696
AACR Meeting Abstracts 2007 2007: 166.  

Erling Borkamo, Olav Dahl, Ove Bruland, and Fluge Oystein
The effect of hyperthermia in combination with metronomic dosed cyclophosphamide: novel molecular mechanisms for the effect of hyperthermia
AACR Meeting Abstracts 2007 2007: 167.  

Yemin Wang, Derek Dai, Magdalena Martinka, and Gang Li
Prognostic significance of ING3 subcellular localization in human cutaneous melanoma and its role in cell growth
AACR Meeting Abstracts 2007 2007: 168.  

Erik Sulman, J. McDonald, Lihong Long, Sonya Popoff, Howard Colman, and Kenneth Aldape
Aquaporin-1 is decreased in long-term survivors of glioblastoma
AACR Meeting Abstracts 2007 2007: 169.  

Virginia Espina, Amy VanMeter, Sharon Smith, Kirsten Edmiston, Emanuel Petricoin, David Geho, and Lance Liotta
Protein stability in human tissue: lability of proteins following biopsy excision establish criteria for room temperature preservation chemistry.
AACR Meeting Abstracts 2007 2007: 170.  

Kerstin Menander, Laura Licato, Robert Sobol, Louis Zumstein, Martha French, Dora Bocangel, Greg Ball, Gary Clayman, Jack Roth, and Sunil Chada
Identification of a predictive molecular biomarker of p53 therapy (adenoviral p53) in patients with recurrent squamous cell carcinoma of the head and neck (SCCHN)
AACR Meeting Abstracts 2007 2007: 171.  

Irmgard Kronberger, Klaus Laimer, Alexander Perathoner, Dietmar Fuchs, Raimund Margreiter, Albert Amberger, and Gerald Brandacher
Increased expression of indoleamine 2,3-dioxygenase contributes to response to adjuvant therapy and overall survival in patients with oral squamous cell carcinoma.
AACR Meeting Abstracts 2007 2007: 172.  

Sung Kuo, Li Chen, Pei Yeh, Yi Tzeng, Kuan Kuo, Jaw Lin, and Ann Cheng
Constitutive BAFF and NF-{kappa}B activation is associated with the H. pylori-independent growth of early-stage gastric diffuse large B-Cell lymphoma with MALT components
AACR Meeting Abstracts 2007 2007: 173.  

Lena Ipsen, Lise Mette Gjerdrum, Christian Poulsen, Peter Jensen, Maxwell Sehested, and Elisabeth Ralfki?r
Expression of histone deacetylases 1 and 2 and histone 4 acetylation in T- and B-cell lymphomas
AACR Meeting Abstracts 2007 2007: 174.  

Stefanie Meyer, Markus Ameres, Michael Landthaler, Frauke Bataille, Matthias Woenckhaus, Albrecht Reichle, Arndt Hartmann, and Peter Johannes Wild
Expression of cyclooxygenase-2 (COX-2) and peroxisome proliferator-activated receptor gamma (PPAR{gamma}) in skin tumors
AACR Meeting Abstracts 2007 2007: 175.  

Nicolas Mottet, Jean-Marc Dumollard, Fabienne Gouzy-Grosjean, Pascale Lucht-Versini, Michel Peoch', Eric Thibaudeau, and Marc Riviere
Expression profiling of M2PK in 19 different human tumor types
AACR Meeting Abstracts 2007 2007: 176.  

Prashant Bavi, Valerie Atizado, Valorie Balde, Fouad Al-Dayel, Adnan Ezzat, Shahab Uddin, and Khawla Al-Kuraya
Lack of cyclin H expression is independent prognostic marker for poor outcome in diffuse large B cell lymphoma
AACR Meeting Abstracts 2007 2007: 177.  

Paulette mhawech-fauceglia, Ahmad arsalan, Gabor fischer, and francois herrmann
Biomarkers expression in T1A and T1B urothelial bladder carcinoma and their value in predicting tumor outcome
AACR Meeting Abstracts 2007 2007: 178.  

Hongyu Zhao, Hongwei Yu, and Weisong Cai
DNA topoisomeraseII-alpha as a proliferation marker in human glioma: correlation with PCNA expression and patient survival
AACR Meeting Abstracts 2007 2007: 179.  

Yoichi Mizutani, Taisuke Toiyama, Takumi Shiraishi, Terukazu Nakamura, Kazuya Mikami, Natsuki Takaha, Koji Okihara, Osamu Ukimura, Akihiro Kawauchi, and Tsuneharu Miki
Enhanced orotate phosphoribosyltransferase activity in bladder cancer and its prognostic significance
AACR Meeting Abstracts 2007 2007: 180.  

Hee Lee, Min Kim, Hye Lee, Byung Lee, and Woo Kim
Characteristics of KIT-negative gastrointestinal stromal tumors and the usefulness of protein kinase C theta as a diagnostic marker
AACR Meeting Abstracts 2007 2007: 181.  

Hedvig Vekony, Frank Raaphorst, C. Leemans, Isaac Van der Waal, and Elisabeth Bloemena
Deregulated expression of Polycomb group genes in salivary gland adenoid cystic carcinoma
AACR Meeting Abstracts 2007 2007: 182.  

Arezou Ghazani, Sarit Aviel-Ronen1, Jeongjin A. Lee, Jesse Klostranec, Qing Xiang, Warren Chan, and Ming Tsao
High throughput quantification of cancer antigens of tumor biopsies: A novel strategy using quantum dot nanocrystals
AACR Meeting Abstracts 2007 2007: 183.  

Kyungeun Kim, Cheryn Song, Hanjong Ahn, and Yong Mee Cho
Immunohistochemical markers for metastatic renal cell carcinomas
AACR Meeting Abstracts 2007 2007: 184.  

Jean-Louis Merlin, Jihane Mriouah, Gilles Dolivet, Carole Ramacci, Marie Rouyer, Pascal Genin, Jean-Louis Formento, Mireille Francoual, and AgnA?s Leroux
Signaling phosphoproteins in head and neck squamous cell carcinoma: Relation with cellular sensitivity to cetuximab and interest of multiplex determination using Bioplex protein array
AACR Meeting Abstracts 2007 2007: 185.  

Ingeborg Bachmann, Oddbjorn Straume, George Naumov, and Lars Akslen
Tumor necrosis is associated with increased {alpha}vβ3 expression and poor prognosis in cutaneous melanoma
AACR Meeting Abstracts 2007 2007: 186.  

Molecular classification of tumors: Poster Presentations - Late-Breaking Abstracts:Back

Mike Heimerikx, Marja Nieuwland, Johannes Huitink, Daoud Sie, Wim Brugman, Cor Lieftink, Jorma de Ronde, Arno Velds, and Ron Kerkhoven
Inhaled anesthetics may compromise gene expression signatures
AACR Meeting Abstracts 2007 2007: LB-159.  

Nitzan Rosenfeld, Ayelet Chajut, Eti Meiri, Meirav Zepeniuk, Norberto Shabes, Sarit Tabak, Karin Ashkenazi, Hila Benjamin, Alex Ben Ari, Nurit Targan, Yael Spector, Dalia Cohen, Zvi Bentwich, and Ranit Aharonov
MicroRNA signature for identification of tumor origin
AACR Meeting Abstracts 2007 2007: LB-160.  

Molecular diagnostics: Poster Presentations - Late-Breaking Abstracts:Back

Masami Muramatsu, Kanako Hoshi, Hideki Takakura, Yasumasa Mitani, Kenji Tatsumi, Nobuyoshi Momiyama, Yasushi Ichikawa, Shinji Togo, Toru Miyagi, Yuki Kawai, Takeshi Kikuchi, Chiaki Kato, Takahiro Arakawa, Syuji Uno, Paul Cizdziel, Alexander Lezhava, Noburou Ogawa, Yoshihide Hayashizaki, and Hiroshi Shimada
Use of the SMart-Amplification Process for rapid detection of EGFR mutations in lung cancer
AACR Meeting Abstracts 2007 2007: LB-161.  

Daniela Gasparotto, S Rossi, A Marzotto, C Sartor, Z Carano, C Bearzi, A Dei Tos, and R Maestro
Multiple gastrointestinal stromal cell tumors (GIST) in an adult, non-NF1 patient
AACR Meeting Abstracts 2007 2007: LB-162.  

Frederik Holst, Phillip Stahl, Christian Ruiz, Zeenath Jehan, Annette Lebeau, Luigi Terracciano, Khawla Al-Kuraya, Fritz JA¤nicke, Guido Sauter, and Ronald Simon
Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer and predicts response to tamoxifen
AACR Meeting Abstracts 2007 2007: LB-163.  

Jon Chan, Liqiang Xi, Raja Seethala, Tony Godfrey, and Ferris Robert
Intraoperative qRT-PCR for detection of lymph node metastasis in head and neck cancer.
AACR Meeting Abstracts 2007 2007: LB-164.  

Lofton-Day Catherine, Fabian Model, Theo DeVos, Volker Liebenberg, Robert Day, and Andrew Sledziewski
Clinical case-control study in plasma shows that the DNA methylation biomarker, Septin 9, detects 70% of Stage I-III colorectal cancer patients
AACR Meeting Abstracts 2007 2007: LB-165.  

Tomasz Wojdacz, Alexander Dobrovic, and Elizabeth Algar
Rapid detection of methylation changes at the H19 differentially methylated region in human imprinting disorders using methylation sensitive high resolution melting.
AACR Meeting Abstracts 2007 2007: LB-166.  

Amy Smith, Michael Pinkney, Nigel Piggott, Ali Kucukmetin, Richard Edmondson, Alan Calvert, Ian Milton, and John Lunec
The development and evaluation of novel monoclonal antibodies to folate receptor alpha and folylpolyglutamate synthetase for use on paraffin embedded samples
AACR Meeting Abstracts 2007 2007: LB-167.  

Prognosis: Poster Presentations - Late-Breaking Abstracts:Back

Marek Svoboda, Pavel Fabian, Ingrid Vasova, Lenka Radova, Jitka Berkovcova, Martin Klabusay, Rudolf Nenutil, and Ales Rejthar
Role of Survivin and Akt in Diffuse Large B-cell Lymphoma. Pilot study.
AACR Meeting Abstracts 2007 2007: LB-168.  

Satoru Iida, Keiji Kato, Shinji Morita, Hiroyuki Uetake, and Kenichi Sugihara
Methylated TMS1 and DAPK genes predict response to chemotherapy in gastric cancer
AACR Meeting Abstracts 2007 2007: LB-169.  

Laboratory correlates/new agents that target signal transduction pathways, growth factors, and cell cycle progression: Poster Presentations - Late-Breaking Abstracts:Back

Cherie-Ann Nathan, Glenn Mills, Xiaohua Rong, David Drummond, Nazanin Amirghahari, Anshul Agarwal, Youhua Rong, Jonathan Glass, and Timothy Lian
An exploratory biomarker trial of an mTOR inhibitor in subjects with newly diagnosed advanced stage squamous cell carcinoma of the head and neck
AACR Meeting Abstracts 2007 2007: LB-170.  

Andrey Frolov, Ching-Wei Tzeng, Nirag Jhala, Natalya Frolova, Salwyn Vickers, Donald Buchsbaum, Martin Heslin, and Juan Pablo Arnoletti
Pancreatic cancer ErbB3 pathway signaling is associated with improved patient survival and in vitro response to anti-EGFR therapy
AACR Meeting Abstracts 2007 2007: LB-171.  

Tumor staging: correlation of clinical and molecular markers: Poster Presentations - Late-Breaking Abstracts:Back

Vitaly Margulis, Michael Shulman, and Elie Benaim
PSA KINETICS FOLLOWING AN EXOGENOUS ANDROGEN CHALLENGE AS A PREDICTOR OF PROSTATE CANCER DIAGNOSIS - A PROSPECTIVE CLINICAL STUDY
AACR Meeting Abstracts 2007 2007: LB-172.  

Brain and central nervous system cancers: Poster Presentations - Late-Breaking Abstracts:Back

Leandro Cerchietti, Alfredo Navigante, Monica Castro, Manuel Martinez, Marcelo Bonomi, and Berta Roth
Oral arginine is a potent radiosensitizer for patients with brain metastases
AACR Meeting Abstracts 2007 2007: LB-173.  

Head and neck cancers: Poster Presentations - Late-Breaking Abstracts:Back

nabil saba, Xu Wang, Mourad Tighiouart, Susan Muller, Kwangjae Cho, Zhuo (Georgia) Chen, Lilly Yang, Fadlo Khuri, Shuming Nie, and Dong Shin
Examining expression of folate receptors in squamous cell carcinoma of the head and neck (SCCHN) as a target for a novel nanotherapeutic drug
AACR Meeting Abstracts 2007 2007: LB-174.  

Susan Mallery, Peter Larsen, Henry Fields, Russell Mumper, and Gary Stoner
Chemopreventive effects of a bioadhesive berry gel on lesions of oral epithelial dysplasia
AACR Meeting Abstracts 2007 2007: LB-175.  

Cellular immunotherapy: Poster Presentations - Late-Breaking Abstracts:Back

Martin Bornhauser, Jana Babatz, Johannes Schetelig, Thomas Illmer, Alexander Kiani, Uwe Platzbecker, Christian Thiede, Ernst Rieber, Gerhard Ehninger, and Marc Schmitz
Adoptive transfer of peptide-reactive donor T cells to prevent relapse of chronic myeloid leukemia after CD34+ selected allogeneic hematopoietic cell transplantation
AACR Meeting Abstracts 2007 2007: LB-176.  

Cytokines, lymphokines and growth factors: Poster Presentations - Late-Breaking Abstracts:Back

Trent Miller, Clint Ellingson, Cliff Ellingson, Marcus Hin-Lee, Michael Larson, Byron Murray, Richard Robison, and Kim O'Neill
Genetic expression of macrophages after exposure to MDA-MB-435S and MCF7 breast cells may determine mechanism for immune system evasion.
AACR Meeting Abstracts 2007 2007: LB-177.  

Radiation resistance: Poster Presentations - Late-Breaking Abstracts:Back

Chen Zhongping, Zhen Hu, Yunfei Xia, and Mintao Li
Proteomic study on molecular machnism of radioresistance in human glioma cell line MGR2 induced by X-ray
AACR Meeting Abstracts 2007 2007: LB-178.  

Genomic instability: Oral Presentations - Late-Breaking Abstracts:Back

Bijan Sobhian, Genze Shao, Aedin Culhane, David Livingston, and Roger Greenberg
Rap80 targets BRCA1 to specific ubiquitin structures at DNA damage sites
AACR Meeting Abstracts 2007 2007: LB-183.  

Novel pro- and antiangiogenic factors: Oral Presentations - Late-Breaking Abstracts:Back

George Yancopoulos
Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis, even for tumors resistant to anti-VEGF therapies
AACR Meeting Abstracts 2007 2007: LB-184.  

Tumor-stromal cell interactions: Oral Presentations - Late-Breaking Abstracts:Back

Makoto Taketo and Takanori Kitamura
A novel mechanism of colon cancer invasion: Role of immature myeloid cells in SMAD4-deficient adenocarcinoma mouse model
AACR Meeting Abstracts 2007 2007: LB-185.  

Epigenetic changes as molecular markers of cancer: Oral Presentations - Late-Breaking Abstracts:Back

Aparna Raval, Stephan Tanner, John Byrd, Elizabeth Angerman, James Perko, Shih-Shih Chen, Bjorn Hackanson, Michael Grever, David Lucas, Jennifer Matkovic, Thomas Lin, Thomas Kipps, Fiona Murray, Dennis Weisenburger, Warren Sanger, Jane Lynch, Patrice Watson, Mary Jansen, Yuko Yoshinaga, Richard Rosenquist, Pieter de Jong, Penny Coggill, Stephan Beck, Henry Lynch, Albert de la Chapelle, and Christoph Plass
Loss or reduced expression of DAPK1 contributes to heritable predisposition to CLL
AACR Meeting Abstracts 2007 2007: LB-186.  

Tumor Proteins in NSCLC and Gastrointestinal Cancers: Poster Presentations:Back

Sarit Aviel-Ronen, Melania Pintilie, Davina Lau, Serge Jothy, and Ming-Sound Tsao
Does Glypican 3 expression in non-small cell lung cancer suggest an oncogenic function?
AACR Meeting Abstracts 2007 2007: 187.  

David Hayes, Carrie Lee, Patrick Roberts, Mary Beth Bell, Leigh Thorne, Jason Schallheim, Phil Bernard, and Bill Funkhouser
Subtypes of lung adenocarcinoma derived from gene expression patterns are recapitulated using a tissue microarray system and immunohistochemistry
AACR Meeting Abstracts 2007 2007: 188.  

Isabelle Opitz, Alex Soltermann, Martin Abaecherli, Nicole Probst, Valentin Rousson, Didier Lardinois, Rolf Stahel, and Walter Weder
PTEN expression in human mesothelioma tissue is a strong predictor of survival
AACR Meeting Abstracts 2007 2007: 189.  

Carmen Behrens, Heather Lin, J Lee, Waun Hong, Ignacio Wistuba, and Reuben Lotan
Differential immunohistochemical expression patterns of fibroblast growth factor-2, receptors 1 and 2, and syndecan-1 in squamous cell carcinoma and adenocarcinoma of the lung
AACR Meeting Abstracts 2007 2007: 190.  

Sven Hillinger, Michela Silacci, Stephan Arni, Simon Brack, Walter Weder, and Dario Neri
High expression of tenascin-C extra domains, markers of angiogenesis, in human lung cancer
AACR Meeting Abstracts 2007 2007: 191.  

Marina Simian, Laura Mauro, Liliana Dalurzo, Gabriel Aguero, Jose Lastiri, Maria Pallotta, David Smith, Bartolome Vasallo, Elisa Bal de Kier Joffe, and Lydia Puricelli
Estrogen and progesterone receptors expression in resected stage I and II in non-small cell lung cancer cells (NSCLC)
AACR Meeting Abstracts 2007 2007: 192.  

Takeshi Kawaguchi, Masayuki Sho, Takashi Tojo, Takeo Nomi, Takahiro Akahori, Kaoru Hamada, Keiji Kushibe, Michitaka Kimura, Yoshiyuki Nakajima, and Shigeki Taniguchi
Significance of prostate stem cell antigen expression in human lung cancer
AACR Meeting Abstracts 2007 2007: 193.  

Keishi Yamashita and Masahiko Watanabe
The most potent prognostic factors among daily-used clinical parameters in gastrointestinal cancers
AACR Meeting Abstracts 2007 2007: 195.  

Ing-Ru Yu, Ricardo Parker, and Eugene Mechetner
Biomarker expression profiles in primary versus metastatic colorectal tumors
AACR Meeting Abstracts 2007 2007: 196.  

Lizhi Zhang, Suresh Chari, and Thomas Smyrk
Expression of PRL-3 in pancreatic ductal adenocarcinoma and its precursors and the association with survival
AACR Meeting Abstracts 2007 2007: 197.  

Hye Lee, Hee Lee, Min Kim, Ji Kim, Sung-Bum Cho, Ju Kim, Han-Kwang Yang, and Woo Kim
Protein expression profiling and molecular classification of gastric cancer using tissue array method
AACR Meeting Abstracts 2007 2007: 198.  

Brooke Sylvester, Andrey Khramtsov, Dezheng Huo, Maria Tretiakova, Lise Sveen, and Olufunmilayo Olopade
Disparities in colorectal cancer: Retrospective analysis of mismatch repair genes and molecular targets
AACR Meeting Abstracts 2007 2007: 199.  

A. Lockhart, Bonnie LaFleur, Nipun Merchant, M. Washington, Elizabeth Johnston, Murray Resnick, and Wooin Lee
Organic anion transporting polypeptide 1B3 (OATP1B3) overexpressed in colorectal tumors may be a predictor of clinical outcome.
AACR Meeting Abstracts 2007 2007: 200.  

Yuan-Jia Chen, Yue-Ning Zhang, Hai-Yan Wu, Mei Mei, Hui-Zhong Qiu, and Chong-Mei Lu
Up-regulation of S100P in human sporadic colorectal cancer and its clinical significance
AACR Meeting Abstracts 2007 2007: 201.  

James Helm, Barbara Centeno, Domenico Coppola, Mihaela Druta, Jong Park, Dung-Tsa Chen, Said Sebti, and Mokenge Malafa
Cancer cell proliferation rate predicts survival following resection of pancreatic adenocarcinoma
AACR Meeting Abstracts 2007 2007: 202.  

Yutaka Shimada, Fumiaki Sato, Tetsuo Ito, Atsushi Itami, Go Watanabe, and Jiro Fujimoto
Prognostic significance of PTTG1/securin in esophageal cancer patients
AACR Meeting Abstracts 2007 2007: 203.  

Rolf Wolthuis, Pierre Jeannesson, Dominique Guenot, Marie-Pierre Gaub, Michel Manfait, and Olivier Piot
Molecular histology of xenografted colon tumors by infrared micro-imaging.
AACR Meeting Abstracts 2007 2007: 204.  

Xu Jia, Venkat Katkoori, Tom Callens, Chandra Shanmugam, Nirag Jhala, Ludwine Messiaen, William Grizzle, and Upender Manne
Immunohistochemical staining patterns of Smad4 expression based on 18q deletions in colorectal adenocarcinomas
AACR Meeting Abstracts 2007 2007: 205.  

ming li and jin gu
Colorectal cancer or colon and rectal cancer: A clinicopathological comparison between colon and rectal carcinomas
AACR Meeting Abstracts 2007 2007: 206.  

Hee Song, Chul Woo Kim, Byung Lan Lee, Woo Ho Kim, and Mee Soo Chang
E-cadherin and beta-catenin expression, and Epstein-Barr virus in gastric adenocarcinomas.
AACR Meeting Abstracts 2007 2007: 207.  

Julien Domont, Armelle Bardier, Catherine Genestie, Jean-Charles Soria, Julien Taieb, Agnes Bellanger, Laurent Hannoun, David Khayat, Frederique Capron, and Jean-Philippe Spano
Assessment of response to cetuximab combined with chemotherapy in metastatic colorectal cancer according to differential expression of biomarkers (EGFR, VEGF, pAKT and PTEN) in a monocentric study
AACR Meeting Abstracts 2007 2007: 208.  

James Helm, Barbara Centeno, Domenico Coppola, Mihaela Druta, Jong Park, Dung-Tsa Chen, Said Sebti, and Mokenge Malafa
Apoptosis rate is a practical intermediate end-point (IEP) biomarker for pre-surgical trials of novel agents in pancreatic cancer
AACR Meeting Abstracts 2007 2007: 209.  

Hiroshi Makino, Masao Miyashita, Tsutomu Nomura, Ken Takahashi, Ichiro Akagi, Nobutoshi Hagiwara, Koji Sasajima, Edward Gabrielson, and Takashi Tajiri
Expression of platelet-derived growth factor (PDGF) beta in esophageal carcinomas.
AACR Meeting Abstracts 2007 2007: 210.  

Ren Shumei and Hatakeyama Masanori
Structural basis and functional consequence of helicobacter pylori cagA multimerization in cells
AACR Meeting Abstracts 2007 2007: 211.  

Miscellaneous topics: Oral Presentations - Late-Breaking Abstracts:Back

Daron Brown
High Sustained Efficacy of a Prophylactic Quadrivalent Human Papillomavirus (HPV) (Types 6, 11, 16, 18) L1 Virus-Like Particle (VLP) Vaccine against Cervical Intraepithelial Neoplasia (CIN) grades 2/3 and adenocarcinoma in situ (AIS)
AACR Meeting Abstracts 2007 2007: LB-187.  

Megan Hitchins, Justin Wong, Graeme Suthers, Catherine Suter, David Martin, Nicholas Hawkins, and Robyn Ward
Transgenerational inheritance of a reversible germline epimutaiton of MLH1 predisposing to cancer.
AACR Meeting Abstracts 2007 2007: LB-379.  

Gene expression: Poster Presentations - Late-Breaking Abstracts:Back

Yuanyuan Li and Shih-Hsin Lu
Smad-dependent Transcriptional Activation of esophageal cancer related gene 1 (ECRG1) is upregulated by transforming growth factor-β induction.
AACR Meeting Abstracts 2007 2007: LB-189.  

Su Dao, Maurizio Affer, C. Liu, J. Olsen, Q. Mo, A. Viali, D. Wisniewski, C. Lambek, T. Marr, and Bayard Clarkson
Gene expression profiles of human hematopoietic quiescent (G0)/CD34+ cells from CML patients and control Bone Marrow
AACR Meeting Abstracts 2007 2007: LB-190.  

Tilak Sundaresan, Howard Fine, and Benjamin Purow
The Notch ligand Delta-like-1 regulates Rheb expression and mTOR activity through a Notch-independent mechanism
AACR Meeting Abstracts 2007 2007: LB-191.  

Chromatin structure and function: Poster Presentations - Late-Breaking Abstracts:Back

Karen Meaburn, Prabhakar Gudla, Stephen Lockett, and Tom Misteli
Towards breast cancer diagnostics based on interphase spatial genome positioning
AACR Meeting Abstracts 2007 2007: LB-192.  

Mechanisms of transcription: Poster Presentations - Late-Breaking Abstracts:Back

Veronica Gonzalez-Pena, Daekyu Sun, and Laurence Hurley
Molecular interactions of Nucleolin with the c-Myc G-quadruplex structure
AACR Meeting Abstracts 2007 2007: LB-193.  

Adriana DeSiervi, Jonathan Jacobs, Gabriella Rustici, and Kevin Gardner
Could BRCA1 be a master switch for transcriptional control of genome stability?
AACR Meeting Abstracts 2007 2007: LB-194.  

Oncogenic transcription factors: Poster Presentations - Late-Breaking Abstracts:Back

Wendy Roeb, Antonia Boyer, Webster Cavenee, and Karen Arden
PAX3-FOXO1 controls expression of the p57Kip2 cell cycle regulator through degradation of EGR1
AACR Meeting Abstracts 2007 2007: LB-195.  

Nagalakshmi Nadiminty, Wei Lou, Soo Lee, and Allen Gao
NF-{kappa}B2 p52 promotes androgen-independent growth of LNCaP prostate cancer cells
AACR Meeting Abstracts 2007 2007: LB-196.  

Promoters and enhancers of transcription: Poster Presentations - Late-Breaking Abstracts:Back

Jennifer Locke, Kishor Wasan, Emma Guns, Colleen Nelson, and Carlos Leon
Upregulation of STAT1 transcription activator by an androgen agonist in prostate cancer cells affects intracellular cholesterol esterification
AACR Meeting Abstracts 2007 2007: LB-197.  

RNA interference: Poster Presentations - Late-Breaking Abstracts:Back

Johannes Fruehauf, Shuanglin Xiang, Hongian Guo, Thu Nguyen, Youxin Yang, and Chiang Li
Bacteria deliver RNA Interference in vitro and in vivo for cancer therapy
AACR Meeting Abstracts 2007 2007: LB-198.  

JIEUN YU, Young-Kook Kim, Seong Yeon Park, Dong Hyuk Kim, Keun Hur, Hyuk-Joon Lee, Han-Kwang Yang, and V. Narry Kim
Functions of microRNAs in gastric cancer
AACR Meeting Abstracts 2007 2007: LB-199.  

Posttranscriptional and translational control: Poster Presentations - Late-Breaking Abstracts:Back

Wai Lung Lai and Nai Sum Wong
The identification of sequence elements that mediate stabilization of the CHOP/Gadd153 mRNA by N-(4-hydroxyphenyl)retinamide (4HPR/fenretinide)
AACR Meeting Abstracts 2007 2007: LB-200.  

AACR-Minorities in Cancer Research Jane Cooke Wright Lecture: Oral Presentations - Invited Abstracts:Back

Harold Freeman
The meaning of race in science and in society
AACR Meeting Abstracts 2007 2007: LE02-01.  

Advances in Nanotechnology Applications for Cancer Research: Oral Presentations - Invited Abstracts:Back

Jongyoon Han
Integrated microsystems for multiplexed, high dynamic range cancer biomarker detection
AACR Meeting Abstracts 2007 2007: SS02-01.  

Inflammation and Cancer: Oral Presentations - Invited Abstracts:Back

Yinon Ben-Neriah, Ilan Stein, Elad Horwitz, Rinnat Porat, Rinat Abramovitch, Eithan Galun, and Eli Pikarsky
Tracking the progression of hepatocellular carcinoma in mouse models
AACR Meeting Abstracts 2007 2007: SY02-01.  

Regulation of transcription factor function: Poster Presentations - Late-Breaking Abstracts:Back

Abhinav Jain and Anil Jaiswal
GSK-3β acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2
AACR Meeting Abstracts 2007 2007: LB-201.  

KangAe Lee, John LaPres, Justin McCormick, and Sandra O'Reilly
The biphasic role of prolyl hydroxylase domain protein 2 (PHD2/EGLN1) in modulating tumor-forming potential
AACR Meeting Abstracts 2007 2007: LB-202.  

Jong Seok Moon, Min Young Lee, and Kyung Sup Kim
Activation of cytomegalovirus IE promoter in androgen-dependent prostate cancer cells
AACR Meeting Abstracts 2007 2007: LB-203.  

Min Young Lee, Sarah Yoon, Jong Seok Moon, and Kyung-Sup Kim
ATP-citrate lyase gene is transcriptionally regulated by androgen in prostate cancer cell lines
AACR Meeting Abstracts 2007 2007: LB-204.  

Stephan Brown, Konjeti Sekhar, Soumya Sasi, and Michael Freeman
ATF3 Represses Nrf2-Regulated Phase II Gene Expression
AACR Meeting Abstracts 2007 2007: LB-205.  

DNA methylation: Poster Presentations - Late-Breaking Abstracts:Back

Hulya Yazici, Hui-Chen Wu, Hulya Tigli, Elif Akisik, Rejin Kebudi, Inci Ayan, Gonul Peksayar, Nejat Dalay, and Regina Santella
Genome-wide methylation levels in peripheral blood and tumor tissue of retinoblastoma patients and their healthy siblings
AACR Meeting Abstracts 2007 2007: LB-206.  

Megan Hitchins, Vita Ap Lin, Andrew Buckle, Kayfong Cheong, Nimita Halani, Chau-To Kwok, Deborah Packham, Catherine Suter, Alan Meagher, Susan Clark, Nicholas Hawkins, and Robyn Ward
Co-ordinate epigenetic silencing of a cluster of 3p22 genes flanking MLH1 in sporadic microsatellite unstable colorectal cancer.
AACR Meeting Abstracts 2007 2007: LB-207.  

Amaia Lujambio, Santiago Ropero, Esteban Ballestar, Mario Fraga, Celia Cerrato, Fernando Setien, Sara Casado, Ana Suarez-Gauthier, Montserrat Sanchez-Cespedes, Anna Gitt, Inmaculada Spiteri, Partha Das, Carlos Caldas, Eric Miska, and Manel Esteller
Genetic unmasking of an epigenetically silenced microRNA in human cancer
AACR Meeting Abstracts 2007 2007: LB-208.  

Kornel Schuebel and Stephen Baylin
Comparing the DNA hypermethylome with gene mutations in human colorectal cancer
AACR Meeting Abstracts 2007 2007: LB-209.  

Marina Bibikova, Jose Martin-Subero, Eliza Wickham-Garcia, Julia Richter, Esteban Ballestar, Lidia Lopez-Serra, Marc Seifert, Ralf Kuppers, Manel Esteller, Jian-Bing Fan, David Barker, and Reiner Siebert
DNA methylation profiling in Hodgkin lymphomas using universal bead arrays.
AACR Meeting Abstracts 2007 2007: LB-210.  

Shinwu Jeong, Gangning Liang, Gerda Egger, Joy Lin, Christine Yoo, and Peter Jones
Maintenance and de novo DNA methyltransferases differentially interact with nucleosomes
AACR Meeting Abstracts 2007 2007: LB-211.  

Immune Suppression and Escape: Poster Presentations:Back

Shuang Wei, Andrew Shreiner, Nobu Takeshita, and Alfred Chang
Upregulation of PD-1 on tumor-primed effector T cells by the presence of pre-existent tumor
AACR Meeting Abstracts 2007 2007: 212.  

Kara Doffek, Xiaocia Yan, Sonia Sugg, Bryon Johnson, and Joel Shilyansky
Neuroblastoma express phosphatidlyserine: mechanism for immune evasion
AACR Meeting Abstracts 2007 2007: 213.  

Joelle Riond, Bent Rubin, Laetitia Courtiade, Nicolas Roullet, Frederic Girard, Chantal Etievant, and Jean Edouard Gairin
Immunological and pharmacological induction of MHC-I molecules on murine B16 melanoma to revert tumor escape to immune surveillance
AACR Meeting Abstracts 2007 2007: 214.  

Masoud Manjili, Maciej Kmieciak, Catherine Dumur, and Keith Knutson
HER-2/neu antigen loss and relapse of mouse mammary carcinoma are actively induced by T cell-mediated anti-tumor immune responses: role of IFN-{gamma}
AACR Meeting Abstracts 2007 2007: 215.  

Dipyaman Ganguly, Austin Raymond, Dafydd Thomas, David Lucas, Kenneth Lee, and Dennis Hughes
Inactivated tumor infiltrating CD8+ T cells in primary and metastatic osteosarcoma
AACR Meeting Abstracts 2007 2007: 216.  

Uddalak Bharadwaj, Min Li, Rongxin Zhang, Changyi Chen, and Qizhi Yao
Elevated IL-6 and G-CSF in human pancreatic cancer cell conditioned medium suppress dendritic cell differentiation and activation
AACR Meeting Abstracts 2007 2007: 217.  

Satoshi Watanabe, Rongxiu Zheng, Katsuya Deguchi, Li-Xin Wang, Peter Cohen, and Suyu Shu
Tumor-induced CD11b+Gr-1+ myeloid cells promote tumor growth and regulate T cell sensitization in the draining lymph node
AACR Meeting Abstracts 2007 2007: 218.  

Yueh-Fu Fang, Yu-Ming Wang, How-Wen Ko, Chien-Ying Liu, Chih-Hsia Kuo, Meng-Heng Hsieh, Chih-Liang Wang, Kang-Yun Lee, Hao-Chen Chen, Chih-Teng Yu, and Han-Pin Kuo
Immune alterations and M1/M2 shifting of monocytes in patients with non-small cell lung cancer
AACR Meeting Abstracts 2007 2007: 219.  

Mary Litzinger, Romaine Fernando, Tyler Curiel, Jeffrey Schlom, and Claudia Palena
Importance of dose scheduling of denileukin diftitox/vaccine combination therapy to reduce T regs and to enhance immune responses
AACR Meeting Abstracts 2007 2007: 220.  

Chiara Castelli, Francesca Rini, Chiara Casati, Chiara Camisaschi, Arabella Mazzocchi, Frederic Triebel, and Giorgio Parmiani
LAG-3 (CD223) molecule is preferentially expressed in human CD4+CD25+ T cells displaying suppressor activity
AACR Meeting Abstracts 2007 2007: 221.  

Shin Wha Lee, Ha-Young Lee, Jung-Nam Lee, Yong-Man Kim, Young-Tak Kim, and Joo-Hyun Nam
Comparison of proportion of CD4+CD25high+FoxP3+ regulatory T cells in ex vivo expansion of ascites from patients with primary and recurrent ovarian carcinoma
AACR Meeting Abstracts 2007 2007: 222.  

Mehdi Fini and Nathan Pennock
Decrease in CD4+CD25-/CD4+CD25+ Treg ratio in thoracic lymph nodes in early stage of lung carcinogenesis: reversal by {alpha}-Tocopheryl succinate in vitro and implications for lung cancer Immunotherapy
AACR Meeting Abstracts 2007 2007: 223.  

Alexander Muller, James DuHadaway, Tinku Banerjee, David Munn, Andrew Mellor, Paul Gaspari, William Malachowski, and George Prendergast
Brassinin compounds exhibit anti-cancer activity mediated through inhibition of the immunotolerogenic enzyme Indoleamine 2,3-dioxygenase (IDO)
AACR Meeting Abstracts 2007 2007: 224.  

Irmgard Kronberger, Birgit Troster, Klaus Laimer, Dietmar Fuchs, Petra Obexer, Raimund Margreiter, Albert Amberger, and Gerald Brandacher
Increased enzyme activity of indoleamine 2,3-dioxygenase (IDO) in tumor cells facilitates immune escape and leads to enhanced metastases
AACR Meeting Abstracts 2007 2007: 225.  

Million Arefayene, Santosh Philips, Cao Donghua, Flockhart David, Wilkes David, and Skaar Todd
Functional analysis of the indoleamine 2,3 dioxygenase genetic variants
AACR Meeting Abstracts 2007 2007: 226.  

C.S. Cho and K.N. Leung
In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus in murine models and in tumor-bearing mice
AACR Meeting Abstracts 2007 2007: 227.  

Brian Wulff, Kathleen Tober, Mitch Phelps, F Ducan, Anne Vanbuskirk, Donna Kusewitt, James Dalton, and Tatiana Oberyszyn
Effects of therapeutic immunosuppressants on progression of UVB induced skin tumors.
AACR Meeting Abstracts 2007 2007: 228.  

Francesca Milano, Agnieszka Rygiel, Jacques Bergman, Martien Kapsenberg, Maikel Peppelenbosch, and Kausilia Krishnadath
Tumor microenvironment in esophageal adenocarcinoma: A fight between immunity and tolerance
AACR Meeting Abstracts 2007 2007: 229.  

Kaushik Biswas, Matthew Simmons, Amy Richmond, Patricia Rayman, Ali Chahlavi, Soumika Biswas, Michael Vogelbaum, Charles Tannenbaum, Ronald Bukowski, and James Finke
Ganglioside mediated suppression of Th1(IFN-gamma) response in T cells
AACR Meeting Abstracts 2007 2007: 230.  

Zenta Tsuchihashi, Beihong Hu, Gregg Masters, Anne Lewin, Jeffrey Hulmes, Alan Korman, Jason Payseur, Bing Chen, Pina Caldarelli, and Maria Jure-Kunkel
Biomarker analyses following the anti-CTLA-4 treatment in mouse tumor models
AACR Meeting Abstracts 2007 2007: 231.  

Eijun Itakura, Rong-Rong Huang, Duan-Ren Wen, and Alistair Cochran
Localization of IL-10 mRNA in different cells in sentinel and non-sentinel nodes of melanoma patients by the RT in situ PCR technique
AACR Meeting Abstracts 2007 2007: 232.  

Roberto Carrio, Marta Torroella-Kouri, and Diana Lopez
Thymic involution in tumor-bearing mice: Role of the microenvironment.
AACR Meeting Abstracts 2007 2007: 233.  

Melissa Aldrich, Andrew Sharabi, and Si-Yi Chen
Twist-2 plays an important role in regulation of thymocyte development and T-cell function
AACR Meeting Abstracts 2007 2007: 234.  

DNA methylation inhibitors: Poster Presentations - Late-Breaking Abstracts:Back

Mitali Pandey and Sanjay Gupta
Green tea polyphenols inhibit promoter hypermethylation through downregulation of DNMT expression in prostate cancer LNCaP cells
AACR Meeting Abstracts 2007 2007: LB-212.  

Epigenetic changes as molecular markers of cancer: Poster Presentations - Late-Breaking Abstracts:Back

Hulya Yazici, Mary Terry, Ruby Senie, Irene Andrulis, and Regina Santella
Changes in DNA methylation patterns in plasma DNA of breast cancer cases and their healthy siblings prior to diagnosis
AACR Meeting Abstracts 2007 2007: LB-213.  

Patricia Galipeau, Marina Bibikova, Xiaohong Li, Dennis Chao, Carissa Sanchez, Kevin Gunderson, and Brian Reid
CpG methylation of 807 genes in patients with Barrett's esophagus
AACR Meeting Abstracts 2007 2007: LB-215.  

Rafael Guerrero-Preston, Regina Santella, Adolfo Blanco, Maria Berdasco, Esteban Ballestar, Mario Fraga, and Manel Esteller
Global DNA hypomethylation patterns in hepatocellular carcinoma cases and controls
AACR Meeting Abstracts 2007 2007: LB-216.  

Gene silencing: Poster Presentations - Late-Breaking Abstracts:Back

Liqiang Xi, Andrew Feber, Vanita Gupta, Maoxin Wu, Rodney Landreneau, Virginia Litle, James Luketich, and Tony Godfrey
Identification of cancer-related genes that are alternatively spliced at high frequency in lung adenocarcinoma using whole genome exon arrays
AACR Meeting Abstracts 2007 2007: LB-217.  

Genomic imprinting: Poster Presentations - Late-Breaking Abstracts:Back

Ronghua Zhao, Myriam Oviedo, Steven Wexner, Mariana Berho, Juan Nogueras, Eric Weiss, Dana Sands, Francis Giardiello, and Marcia Cruz-Correa
Genotype-Phenotype Correlation of Loss of Imprinting of IGF2 in Colorectal Cancer Patients
AACR Meeting Abstracts 2007 2007: LB-218.  

Hisashi Abe, Baojin Fu, Mingde Luo, Felip Villelas, Clark Henderson, Alison Klein, Michael Borges, Michael Goggins, and Christine Donahue
Loss of Imprinting of IGF-2 in Pancreatic Carcinogenesis
AACR Meeting Abstracts 2007 2007: LB-219.  

Control of cell cycle progression: Poster Presentations - Late-Breaking Abstracts:Back

Eunsil Hahm, Dong-Hoon Jin, Jae Seung Kang, Young-In Kim, Seung-Woo Hong, Seung Koo Lee, Da Jung Jung, Jee Eun Kim, Dong Hoon Shin, Young Il Hwang, and Wang Jae Lee
The molecular mechanisms of vitamin C on cell cycle regulation in B16F10 murine melanoma
AACR Meeting Abstracts 2007 2007: LB-220.  

Zheng Fu, Junjie Chen, and Donald Tindall
Plk1 regulates FoxM1 activity during G2-M phase
AACR Meeting Abstracts 2007 2007: LB-221.  

Cell cycle checkpoints: Poster Presentations - Late-Breaking Abstracts:Back

Ying Yan, Claudine Black, and Kenneth Cowan
Irradiation-induced G2/M checkpoint response requires ERK1/2 activation
AACR Meeting Abstracts 2007 2007: LB-222.  

Aimin Peng and James L. Maller
A Threshold Amount of Undamaged DNA Is Required to Transmit and Enhance DNA Damage Checkpoint Signals in Early Xenopus Embryos
AACR Meeting Abstracts 2007 2007: LB-223.  

Cyclins: Poster Presentations - Late-Breaking Abstracts:Back

Ruiyang Tian, Daniel Silver, Jean Zhao, Yan Li, Yan Geng, James Iglehart, Andrea Richardson, and Zhigang Wang
Cyclin E2 deregulation induces tetraploidy: A potential role of chromosome 8q22 amplification in pathogenesis of breast cancers.
AACR Meeting Abstracts 2007 2007: LB-224.  

Vanita Gupta, Andrew Feber, Liqiang Xi, Arjun Pennathur, Maoxin Wu, James Luketich, and Tony Godfrey
CCND1 polymorphism and expression in esophageal adenocarcinoma
AACR Meeting Abstracts 2007 2007: LB-225.  

Phosphorylation and proteolysis in cell cycle control: Poster Presentations - Late-Breaking Abstracts:Back

Kara Lukasiewicz, Tammy Greenwood, Jeffrey Salisbury, and Wilma Lingle
Phosphorylation of Centrin 2 by Aurora A: Implications for Centrin 2 degradation
AACR Meeting Abstracts 2007 2007: LB-226.  

Rong Yu, Jun Ye, and Zheyi Han
A Cullin 3-based ubiquitin ligase controls ubiquitination of retinoblastoma protein and enhances cell proliferation
AACR Meeting Abstracts 2007 2007: LB-227.  

Homologous recombination: Poster Presentations - Late-Breaking Abstracts:Back

Ramune Reliene, Mitsuko Yamamoto, Alan D'Andrea, and Robert Schiestl
Murine Fanconi anemia genes Fancg and Fancd2 have different functions in regulation of homologous recombination
AACR Meeting Abstracts 2007 2007: LB-229.  

lucy riches, Anthony Lynch, and Nigel Gooderham
Visualising RAD52 mRNA upregulation in whole cells in response to DNA double strand breaks
AACR Meeting Abstracts 2007 2007: LB-230.  

Genomic instability: Poster Presentations - Late-Breaking Abstracts:Back

Patricia McChesney, Stacy Williams, Andrei Thomashevski, Valia Milhaylova, and Gary Kupfer
The Fanconi anemia protein, FANCJ binds to, and regulates chromatin loading of FANCD2
AACR Meeting Abstracts 2007 2007: LB-231.  

Epigenetic Markers of Cancer 1: Poster Presentations:Back

Jaroslav Jelinek, Vazganush Gharibyan, Rong He, Amanda Saraf, Samantha Lau, Josef Prchal, and Jean-Pierre Issa
DNA methylation of HOX genes in leukemia and myeloproliferative disorders
AACR Meeting Abstracts 2007 2007: 235.  

Luis Acevedo, Mark Bieda, Roland Green, and Peggy Farnham
Chromatin modification and virtual CGH in liver cancer using ChIP-on-chip studies
AACR Meeting Abstracts 2007 2007: 236.  

Mohammad Hoque, Myong kim, Kimberly Ostrow, Junwei Liu, G. Bea A Wisman, Carmen Jeronimo, Henerique Rui, Straub Josef, Hannah Lui, Luana Poeta, Shahnaz Begum, Eli Rosenbaum, Keshi Yamashita, Joseph Califano, William Westra, Ate G.J Van der Zee, Wim Criekinge, and David Sidransky
Genome-wide promoter analysis uncovers portions of the cancer "Methylome" in primary tumors and cell lines
AACR Meeting Abstracts 2007 2007: 237.  

Mary Beth Terry, Rick Pilsner, Jennifer Ferris, Julie Flom, Mary Gamble, and Regina Santella
Global hypomethylation among women in a New York City birth cohort
AACR Meeting Abstracts 2007 2007: 238.  

Shu Zhang, Michael Chan, Curt Balch, Pearlly Yan, Dhaval Desai, John Montgomery, Tim Huang, and Kenneth Nephew
Identification and characterization of cancer stem-like cells from human ovarian carcinomas
AACR Meeting Abstracts 2007 2007: 239.  

hongchuan jin, Xian Wang, Jianming Ying, Ada HY Wong, Kwan Yeung Lee, Gopesh Srivastava, Zhongying Shen, Liyan Xu, Anthony TC Chan, and Qian Tao
Integrative epigenetics identifies a novel 16q23 tumor suppressor gene ADAMTS18 silenced by methylation in multiple tumors
AACR Meeting Abstracts 2007 2007: 240.  

Mathias Ehrich and Dirk van den Boom
Identifying epigenetic biomarkers using large-scale cytosine methylation profiling of ancer cell lines
AACR Meeting Abstracts 2007 2007: 241.  

Bruno Costa, Justin Smith, Ying Chen, Kenneth Aldape, Giuseppe Zardo, Janice Nigro, Heidi Phillips, C. David James, Jane Fridlyand, and Joseph Costello
Chromosomal domains of transcriptional activation by PI3K/AKT pathway alterations in glioblastomas
AACR Meeting Abstracts 2007 2007: 242.  

Shankar Jagadeesh and Partha Banerjee
Mahanine reverses epigenetically silenced tumor suppressor gene RASSF1A in human prostate cancer cells_
AACR Meeting Abstracts 2007 2007: 243.  

Shuji Ogino, Jeffrey Meyerhardt, Takako Kawasaki, Jeffrey Clark, Akiyo Ogawa, David Ryan, Matthew Kulke, Peter Enzinger, Brian Wolpin, Massimo Loda, and Charles Fuchs
CpG island methylation may predict worse survival and poor response to combination chemotherapy in advanced microsatellite stable colorectal cancer
AACR Meeting Abstracts 2007 2007: 244.  

Masayuki Haruta, Hisaya Nakadate, Naoki Watanabe, Masahiro Fukazawa, Hidenobu Soejima, and Yasuhiko Kaneko
Loss of imprinting (LOI) of IGF2 was found in a substantial number of Wilms tumors in Japanese children
AACR Meeting Abstracts 2007 2007: 245.  

Stefano Cairo, Yipeng Wang, Carolina Armengol, Chang-Gong Liu, Michael McClelland, Carlo Croce, and Marie-Annick Buendia
Hepatoblastoma as a model to study the interplay between gene expression, miRNA expression and DNA methylation in development-related tumors.
AACR Meeting Abstracts 2007 2007: 246.  

Kimberly Ostrow, Mohammad Hoque, Carmen Jeronimo, Alissa Greenberg, William Rom, and David Sidransky
Molecular analysis of plasma/sputum DNA for the early detection of lung cancer by quantitative methylation specific PCR
AACR Meeting Abstracts 2007 2007: 247.  

Mathewos Tessema, Malcolm Brock, Chris Stidley, and Steven Belinsky
Profile of gene methylation in lung adenocarcinoma from smokers and never smokers identifies concurrent aberrant methylation of multiple genes by smoking status
AACR Meeting Abstracts 2007 2007: 248.  

Weizhu Zhu, Wenyi Qin, and Edward Sauter
Quantitative evaluation of DNA hypermethylation in breast tumor and normal tissue
AACR Meeting Abstracts 2007 2007: 249.  

Andreas Hoffmann, Jan Brabender, Daniel Vallbohmer, Ralf Metzger, Arnulf Hoelscher, and Paul Schneider
Detection of methylated APC, DAPK and MGMT promoter DNA in peripheral blood is significantly associated with neoadjuvant multimodality treatment.
AACR Meeting Abstracts 2007 2007: 250.  

Dietmar Pils, Brigitte Wolf, Michael Wittinger, Jochen Reibenwein, Bernd Mayer, Dominique Koensgen, Alexander Mustea, Isabelle Cadron, Toon van Gorp, Sven Mahner, Nicole Concin, Dan Cacsire-Castillo Tong, Robert Zeillinger, and Michael Krainer
Whole genome screening for epigenetically silenced genes using a panel of epithelial cancer cell lines
AACR Meeting Abstracts 2007 2007: 251.  

Macarena Vargas, Carolina Bernal, Cynthia Villarroel, Paulina Ibanez, Eudocia Santibanez, and Alejandro Corvalan
Monoallelic methylation of E-cadherin (CDH-1) promoter region is altered in normal gastric mucosa and sporadic diffuse-type gastric carcinoma
AACR Meeting Abstracts 2007 2007: 252.  

Cheryl Lewis, DaWei Bu, and David Euhus
Promoter methylation in nipple duct lavage and fine needle aspiration in relation to breast cancer risk
AACR Meeting Abstracts 2007 2007: 253.  

Dong Kim, Ji Lee, Mi Kim, Young Jung, Jae Park, Han Bae, Jae Kim, Se Kee, Young Yun, and Sang Kim
Hypermethylation of Ras association domain family 1A (RASSF1A) in gallbladder cancer and its relationship with clinicopathological features
AACR Meeting Abstracts 2007 2007: 254.  

Seisho Takeuchi, Yang Yang, Wolf Hofmann, Takayuki Ikezoe, Jacques van Dongen, Tomasz Szczepański, Yoshio Uehara, Claus Bartram, and H. Koeffler
Aberrant methylation in promoter-associated CpG islands of multiple genes in acute lymphoblastic leukemia
AACR Meeting Abstracts 2007 2007: 255.  

Shichun Zheng and John Wiencke
Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma multiform.
AACR Meeting Abstracts 2007 2007: 256.  

Ada Wong, Qian Tao, Jianming Ying, Xian Wang, Fion Sung, Andrew van Hasselt, Mu-Sheng Zeng, Wei Hua Jia, Yi-Xin Zeng, and Anthony Chan
Pharmacologic demethylation identifies UCHL1 as a tumor suppressor gene frequently silenced in nasopharyngeal and multiple other carcinomas
AACR Meeting Abstracts 2007 2007: 257.  

Eiji Sunami, Masaru Shinozaki, Armando Giuliano, and Dave Hoon
Estrogen receptor positive primary breast tumors are more frequently associated with promoter hypermethylation
AACR Meeting Abstracts 2007 2007: 258.  

Sung Kyu Cho, Seung Myung Dong, Hyun-Gyu Lee, Hyun Jin Oh, Jeon Han Park, Se Jong Kim, and Jae Myun Lee
Epigenetic regulation of the novel tumor suppressor gene IRF5 (interferon regulatory factor5)
AACR Meeting Abstracts 2007 2007: 259.  

Mathias Ehrich, Wolf Muller, David Louis, and Dirk van den Boom
Identification of tumor suppressor genes by large-scale profiling of cytosine-methylation in glioblastoma cell lines
AACR Meeting Abstracts 2007 2007: 260.  

Fabricio Costa, Lynne-Marie Postovit, Jared Bischof, Sergey Malchenko, Elizabeth Seftor, Richard Seftor, Maria de Fatima Bonaldo, Marcelo Soares, and Mary Hendrix
Epigenetic analysis of NODAL in multipotent tumor cells and embryonic stem cells
AACR Meeting Abstracts 2007 2007: 261.  

Jun-ichi Akahira, Hirofumi Suzuki, Ikumi Miura, Takashi Suzuki, Takuya Moriya, Yasuhiro Miki, Kiyoshi Ito, Shinichi Hayashi, Nobuo Yaegashi, and Hironobu Sasano
RIZ1 expression in the patients with epithelial ovarian carcinoma: Its correlation with aberrant DNA methylation
AACR Meeting Abstracts 2007 2007: 262.  

Anne-Marie Baird, Nael Al-Sarraf, Steven Gray, and Kenneth O'Byrne
The role of IL-20 in lung cancer-a new epigenetic target?
AACR Meeting Abstracts 2007 2007: 263.  

Signaling pathways: Poster Presentations - Late-Breaking Abstracts:Back

Hyun Ki Park, Jin Sun Yoon, Seo Ju Kim, Byoung Kook Kim, and Young Yiul Lee
Leptin induced proliferation for human gastric cancer cells via STAT3 and ERK1/2 activation
AACR Meeting Abstracts 2007 2007: LB-236.  

Genomic profiling of tumors: Poster Presentations - Late-Breaking Abstracts:Back

Jessica Mei Ng and Tom Curran
SNPs and Chips: SNP and gene expression arrays of the pediatric CNS tumors Atypical Teratoid Rhabdoid Tumor and Choroid Plexus Carcinoma
AACR Meeting Abstracts 2007 2007: LB-238.  

Stefano Volinia, George Calin, Chang-Gong Liu, Hansjuerg Alder, Carlo Croce, and Brian Nickoloff
miRNA signatures separate melanoma from normal epidermis and melanocytes
AACR Meeting Abstracts 2007 2007: LB-239.  

Gianfranco de Feo
Gene expression profiling using RNA from Formalin Fixed, Paraffin Embedded (FFPE) tissue
AACR Meeting Abstracts 2007 2007: LB-240.  

Jen-tsan Chi
Integrative genome analysis of tumor hypoxia phenotypes
AACR Meeting Abstracts 2007 2007: LB-241.  

Andrew Feber, Jin Chen, Liqiang Xi, and Tony Godfrey
miRNA expression profiling using a custom AffymetrixTM miRNA array
AACR Meeting Abstracts 2007 2007: LB-242.  

Anastasios Chanalaris, Diana Brazma, Colin Grace, Junia Melo, Jane Apperley, Tessa Holyoake, and Elizabeth Nacheva
Genome wide copy number variations unique to CML: an array CGH study
AACR Meeting Abstracts 2007 2007: LB-243.  

Andrew Feber, Daniel Nicastri, Liqiang Xi, Weijia Zhang, Yezhou Sun, Maoxin Wu, Arjun Pannethur, William Gooding, Virginia Litle, James Luketich, and Tony Godfrey
Clinical significance of genomic alterations in esophageal adenocarcinoma
AACR Meeting Abstracts 2007 2007: LB-244.  

Anastasios Chanalaris
Copy number variations unique to CML
AACR Meeting Abstracts 2007 2007: LB-245.  

Large-scale approaches to cancer gene discovery: Poster Presentations - Late-Breaking Abstracts:Back

Richard Finnell, Robert Cabrera, Andrei Golovko, Michael McLeod, and William Shawlot
Texas Institute for Genomic Medicine (TIGM): Knocking out all murine genes in embryonic stem cells
AACR Meeting Abstracts 2007 2007: LB-246.  

Asha Collins and The Cancer Genome Atlas Project Team
The Cancer Genome Atlas (TCGA) Pilot Project
AACR Meeting Abstracts 2007 2007: LB-247.  

Integrative cancer biology: Poster Presentations - Late-Breaking Abstracts:Back

Manfred Neuberg, Renee Deehan Kenney, Robin Johnson, Bill Ladd, Biaoyang Lin, Joseph Loureiro, Andrea Matthews, Jefferson Parker, Dexter Pratt, and Keith Elliston
Causal System Modeling: a novel method for identifying molecular mechanisms using multiple ‘omic technologies, and its application to Prostate Cancer.
AACR Meeting Abstracts 2007 2007: LB-250.  

Gene expression profiling: Poster Presentations - Late-Breaking Abstracts:Back

Hui Wang, Robert Ach, Anya Tsalenko, and Bo Curry
Direct miRNA profiling from low-input total RNA: Stepping towards quantitative measurements.
AACR Meeting Abstracts 2007 2007: LB-251.  

Anne-Lise Borresen-Dale, Torbjorn Lindahl, Nina Hagen, Ken Bardsen, Jorgen Aaroe, Marianne Jensen, Lena Kristiansen, Solve S?bo, Per Skane, Fredrik Warnberg, Alan Holligsworth, Praveen Sharma, Derek Tobin, and Anders Lonneborg
Development of customized arrays for blood based gene expression test to detect early stage breast cancer
AACR Meeting Abstracts 2007 2007: LB-252.  

Weijia Zhang, Yezhou Sun, Elisa Wurmbach, Samuel Waxman, Scott Friedman, Josep Llovet, and Erwin Bottinger
A Novel Approach to Identify Differentially Expressed Genes at Various Frequencies and its Application to Meta-analysis of Gene Expression Profiles in Hepatocellular Carcinoma (HCC)
AACR Meeting Abstracts 2007 2007: LB-253.  

New algorithms: Poster Presentations - Late-Breaking Abstracts:Back

Debopriya Das, Wen-Lin Kuo, Yinghui Guan, Zhi Hu, Nick Wang, Nora Bayani, Heidi Feiler, Paul Spellman, Richard Neve, and Joe Gray
An adaptive approach to predicting chemosensitivity of tissue-specific cancer cells
AACR Meeting Abstracts 2007 2007: LB-254.  

Molecular modeling: Poster Presentations - Late-Breaking Abstracts:Back

Sach Mukherjee, Nora Bayani, Naina Shastri, Kevin Hacker, Arunashree Bhamidipati, Erik Gentalen, Uyen Nguyen, David Voehringer, Karl Voss, Tom Yang, Peter Vander Horn, Steven Pelech, Terry Speed, Joe Gray, and Richard Neve
ERK-pathway connectivity is dependent on tumor sub-type
AACR Meeting Abstracts 2007 2007: LB-255.  

New software for data analysis: Poster Presentations - Late-Breaking Abstracts:Back

Stephane Jankowski, Eric Vennemeyer, and Kathryn Hunkapiller
Direct Sequencing Quality Control: a Novel Software Approach to Reducing Variant Review Time and Labor
AACR Meeting Abstracts 2007 2007: LB-256.  

Protease inhibitor systems: Poster Presentations - Late-Breaking Abstracts:Back

Rafael Madero, Thomas Shellenberger, Adel El Naggar, Arumugam Jayakumar, and Gary Clayman
Expression of LEKTI Correlates with Perineural Invasion in Oral Cavity Carcinoma
AACR Meeting Abstracts 2007 2007: LB-259.  

Cell adhesion and extracellular matrix: Poster Presentations - Late-Breaking Abstracts:Back

Karolina Lindberg, Anders Strom, Jan-Ake Gustafsson, and Michel Tujague
Estrogen receptor beta increases adhesion of T47-D breast cancer cells to extracellular matrix proteins
AACR Meeting Abstracts 2007 2007: LB-260.  

Yasushi Shintani, Margaret Wheelock, and Keith Johnson
ADH-1 suppresses N-cadherin-dependent pancreatic cancer progression
AACR Meeting Abstracts 2007 2007: LB-261.  

Kun Zhang and Ming-Hai Wang
Differential regulation of claudin expression and localization by oncogenic variant of the RON receptor tyrosine kinase*
AACR Meeting Abstracts 2007 2007: LB-262.  

Inflammation and tumor progression: Poster Presentations - Late-Breaking Abstracts:Back

Andrew Retzinger, James Cash, Michael Dentler, Robert Thacker, Michael Walker, and Gregory Retzinger
Extracellular transport of tumor cells by mature dendritic cells: A new idea on metastasis
AACR Meeting Abstracts 2007 2007: LB-263.  

Expression profiling of tumor progression and metastasis: Poster Presentations - Late-Breaking Abstracts:Back

Lin Yu-Hsin, Ahmad Anjomshoaa, Sarah Song, Michael Black, John McCall, and Anthony Reeve
A proliferation gene signature can predict clinical outcome of multiple cancers
AACR Meeting Abstracts 2007 2007: LB-264.  

Anusri Tripathi, Chia-Lin King, Antonio de las Morenas, Gregory Antoine, Erwin Hirsch, Maureen Kavanah, Jane Mendez, Michael Stone, Norman Gerry, Marc Lenburg, and Carol Rosenberg
Gene expression abnormalities in histologically-normal breast epithelium of breast cancer patients
AACR Meeting Abstracts 2007 2007: LB-265.  

Emi Arikawa, Yanyang Sun, Siulan Lee, Xiaomei Bao, Savita Prabhakar, Bill Wang, and Jingping Yang
Studying extracellular matrix proteins and cell adhesion molecules in breast tumor oncogenesis with real-time PCR arrays
AACR Meeting Abstracts 2007 2007: LB-266.  

John Giannios, Philip Lambrinos, Esmeralda Seraj, Nick Alexandropulos, and Evagelos Maragudakis
Pegylated trispecific disulfide linked Fv(sdFv) targeting epitopes of EGFR,PTHrP and RANKL conjugated covalently with SATA to vinorelbine eradicated osteolytic and osteoblastic metastasis of breast Ca inhibiting proliferation of tumor associated and bone microvascular endothelial cells inducing ADCC,AMP and type I,II,III PCD.
AACR Meeting Abstracts 2007 2007: LB-267.  

Intracellular Signaling 1: Poster Presentations:Back

Virginia Lopez Martinez, Angela M. Costa, Giuliana Salvatore, Agustin Herrero, Jose Cameselle-Teijeiro, Massimo Santoro, and Ginesa Garcia-Rostan
PIK3CA gene copy number in 116 thyroid carcinomas and 17 thyroid cancer cell lines
AACR Meeting Abstracts 2007 2007: 265.  

Noel Horton, Rachel Reams, and Gregory Ruppert
Nonclinical toxicities associated with enzastaurin, a potent and specific inhibitor of protein kinase C (PKC), in dogs
AACR Meeting Abstracts 2007 2007: 266.  

James Haughian and Andrew Bradford
Protein kinase C alpha (PKC{alpha}) regulates transformation of endometrial cancer cells
AACR Meeting Abstracts 2007 2007: 267.  

Laura Mauro, Valeria Grossoni, Lucas Colombo, Alejandro Urtreger, Marcelo Kazanietz, ChengFeng Yang, Elisa Bal de Kier Joffe, and Lydia Puricelli
PKC delta promotes a more aggressive tumorigenic phenotype in the human pancreatic carcinoma cell line PANC1
AACR Meeting Abstracts 2007 2007: 268.  

Frederic Stauffer, Carlos Garcia-Echeverria, Pascal Furet, Christian Schnell, Stephan Ruetz, Michel Maira, and Christine FRITSCH
Biochemical, cellular and in vivo profiling of a new PI3K inhibitor from the imidazoquinoline series
AACR Meeting Abstracts 2007 2007: 269.  

Bret Stephens, Haiyong Han, Galen Hostetter, Michael Demeure, and Daniel Von Hoff
Overexpression of PRL-1 and PRL-2 in pancreatic cancer cell lines and tumor samples
AACR Meeting Abstracts 2007 2007: 270.  

Ichiro Akagi, Masao Miyashita, Hiroshi Makino, Tsutomu Nomura, Nobutoshi Hagiwara, Ken Takahashi, Kazumitsu Cho, and Takashi Tajiri
The significance of PIK3CA in esophageal squamous cell carcinoma
AACR Meeting Abstracts 2007 2007: 271.  

William Chappell, Linda Steelman, Stephen Abrams, Ellis Wong, Brian Lehmann, David Terrian, Nick Leslie, Peter Downes, Alberto Martelli, Franca Stivala, Massimo Libra, Patrick Navolanic, and James McCubrey
Inhibition of PTEN function increases chemotherapeutic drug and ionizing radiation resistance in breast cancer
AACR Meeting Abstracts 2007 2007: 272.  

Yuangang Liu, James Lagowski, Aaron Sundholm, Alexandra Sundberg, and Molly Kulesz-Martin
Microtubule disruption and tumor suppression by mitogen activated protein kinase phosphatase 4
AACR Meeting Abstracts 2007 2007: 273.  

Jene Choi, Hye-sook Han, Ji-young Song, and Eunsil Yu
The E2-estrogen receptor-Wip1 pathway has a role in estrogen+ breast cancer development
AACR Meeting Abstracts 2007 2007: 274.  

Chi-Wu Chiang, Yi-Chun Kuo, Kai-Yun Huang, and Chung-Hsiang Yang
The B55{alpha} regulatory subunit targets PP2A holoenzyme to regulate Akt activity and cell growth
AACR Meeting Abstracts 2007 2007: 275.  

Ran Zhang, Naren Banik, and Swapan Ray
Combination of ATRA and IFN-gamma modulated signal transduction pathways for induction of apoptosis in human malignant glioblastoma T98G (PTEN-harboring) and U87MG (PTEN-deficient) cells
AACR Meeting Abstracts 2007 2007: 276.  

Rakesh Kumar, Nelson Rhodes, Victoria Knick, Derek Eberwein, Derek Duckett, ShuYun Zhang, Tona Gilmer, Jack Leber, Elena Kleymenova, Rob Geske, Elisabeth Minthorn, Dirk Heerding, and Pearl Huang
GSK690693, a pan-AKT kinase inhibitor with potent pharmacodynamic and antitumor activity in vivo.
AACR Meeting Abstracts 2007 2007: 277.  

Dimpy Koul, Ruijun Shen, jennifer Edge, Eiji Ivado, Yasuko Kondo, Garth Powis, Lynn Kirkpatric, and WK Yung
Targeting PI3K in Human Glioblastoma with PX-866, a small molecule PI3K inhibitor.
AACR Meeting Abstracts 2007 2007: 278.  

Nelson Rhodes, Victoria Knick, Randy McConnell, Timothy Lansing, David Rusnak, Derek Duckett, Tona Gilmer, Jason Kahana, Kimerly Robell, Jack Leber, Anthony Choudhry, Zhihong Lai, Edgar Wood, Susan Strum, Dirk Heerding, Pearl Huang, and Rakesh Kumar
GSK690693, a pan-AKT kinase inhibitor has potent anti-tumor activity and shows additive effect with lapatinib.
AACR Meeting Abstracts 2007 2007: 279.  

Diansheng Zhong, Xiuju Liu, Shi-Yong Sun, Paula M. Vertino, and Wei Zhou
FOXO3a phosphorylation at threonine32 requires both Akt and LKB1 in NSCLC cell lines
AACR Meeting Abstracts 2007 2007: 280.  

Shannon Fortin, Nhan Tran, Kelsey Drake, Benjamin Savitch, Matthew Ennis, Jeffrey Winkles, Joseph Loftus, and Michael Berens
Fn14 induced glioma cell survival is dependent upon Akt2 function
AACR Meeting Abstracts 2007 2007: 281.  

Wey Yeeng Chee, Janet Martin, Robert Baxter, and Deborah Marsh
Functional analysis of ten PTEN mutations associated with cancer or overgrowth syndromes
AACR Meeting Abstracts 2007 2007: 282.  

Jie Zheng and Raymond Novak
Differential effects of TGF-β on PI 3K/Akt/FOXO signaling and epithelial-mesenchymal transition (EMT) in the MCF10A series of human breast epithelial cells
AACR Meeting Abstracts 2007 2007: 283.  

Tura Camilli, Steven Patierno, and Susan Ceryak
Role for Hsp90 and tyrosine phosphorylation in genotoxin-induced phospho-Akt dephosphorylation.
AACR Meeting Abstracts 2007 2007: 284.  

Marie-Claude Dery and Eric Asselin
Cox-2 upregulation by oxytocin is mediated by the PI 3-K/AKT signaling pathway in endometrial cancers
AACR Meeting Abstracts 2007 2007: 285.  

Dongsoon Bae and Susan Ceryak
Significance of AKT and ERK activation in clonogenic survival after Cr6+ exposure and protein tyrosine phosphatase (PTP) inhibition
AACR Meeting Abstracts 2007 2007: 286.  

Kevin Harvey, Trevor Kimbler, Lothar Goretzki, and Mo Saedi
Detection of mTOR/Raptor activity using a 96 well ELISA based assay
AACR Meeting Abstracts 2007 2007: 287.  

Sandaruwan Geeganage, Zhao Hai Lu, Albert Dee, Lillian Sams, Tao Wang, Sophie Boguslawski, Sajan Joseph, and Mei Lai
Utilization of phospho-GSK3b as a cellular and in vivo pharmacodynamic marker to evaluate the activity of AKT pathway inhibitors
AACR Meeting Abstracts 2007 2007: 288.  

Eduardo Farias
PI3K intracellular signaling from cytoplasmic lipid droplets in transformed human mammary epithelial cells
AACR Meeting Abstracts 2007 2007: 289.  

tao wang, Lillian Sams, and Sandaruwan Geeganage
Development of medium throughput cell-based ELISAs to quantitate the activity of PI3K-AKT pathway inhibitors
AACR Meeting Abstracts 2007 2007: 290.  

Sienna Yoast, Anne Oster, Kirsten Mortensen, Birgitte Jepsen, Therese Phillips, Karin Salomon, Zunde Wang, Marianne Thisted, Miu Chau, and Ole Rasmussen
Expression of PTEN, pAkt, pS6, and Cyclin D1 on ER-positive breast cancer tissues using biomarker assays
AACR Meeting Abstracts 2007 2007: 291.  

Piotr Rychahou, L. Andy Chen, Lindsey Jackson, and B. Evers
Targeting the class IA PI3K in human colorectal cancer
AACR Meeting Abstracts 2007 2007: 292.  

Cell motility and migration: Poster Presentations - Late-Breaking Abstracts:Back

CONGFENG XU and Xin Zhang
Regulation of cell migration by lipid raft-mediated CD82 endocytosis
AACR Meeting Abstracts 2007 2007: LB-268.  

Kai Fung WAN, Hong Yan ZHOU, Kong Chu WONG, Nai Ki MAK, Kwok Wai LO, and Sze Tsai WONG
Hepatocyte growth factor increases the metastatic potential of nasopharyngeal carcinoma: role of Akt and JNK pathways
AACR Meeting Abstracts 2007 2007: LB-269.  

hengning ke, Vandy Parron, Steven Akiyama, and John French
BCL2 regulates cell adhesion, spreading and motility through affecting gelsolin function and actin polymerization
AACR Meeting Abstracts 2007 2007: LB-270.  

Helene Pelicano, Weigin lu, Zhao Chen, Yumin Hu, and Peng Huang
CXCL14: A new molecular link between ROS and malignant behavior in breast cancer cells
AACR Meeting Abstracts 2007 2007: LB-271.  

Shalini Adla, Muhua Yang, and Deni Galileo
L1 autocrine stimulation model of motility in breast cancer and glioma cells
AACR Meeting Abstracts 2007 2007: LB-272.  

Regulation of invasion: Poster Presentations - Late-Breaking Abstracts:Back

Hannah Whiteman, Mark Weeks, Sally Dowen, Sayka Barry, John Timms, Nicholas Lemoine, and Tatjana Crnogorac-Jurcevic
The role of S100P in the invasion of pancreatic cancer cells is mediated through cytoskeletal changes and regulation of cathepsin D
AACR Meeting Abstracts 2007 2007: LB-273.  

Suppressors of metastasis: Poster Presentations - Late-Breaking Abstracts:Back

Jeremy Chien, Alfonso Baldi, Giovanni Aletti, Bruno Vincenzi, Ravi Shridhar, and Viji Shridhar
Role of HtrA1 in cell migration and metastasis
AACR Meeting Abstracts 2007 2007: LB-274.  

Imaging of tumor progression and metastasis: Poster Presentations - Late-Breaking Abstracts:Back

Glenn Deng, David Burgess, Sabine Schmachtenberg, Juergen Schmitz, Edward Manna, David Krag, Julian Burke, and Michael Herrler
A new method for enrichment and detection of circulating tumor cells in the peripheral blood of patients with metastatic breast cancer
AACR Meeting Abstracts 2007 2007: LB-275.  

Palamadai Venkatasubramanian, Paul Grippo, Dan Heiferman, Alice Wyrwicz, and Richard Knop
MR Microscopy of premalignant pancreatic lesion in a transgenic mouse model of pancreatic cancer
AACR Meeting Abstracts 2007 2007: LB-276.  

Tumor markers and detection of metastasis: Poster Presentations - Late-Breaking Abstracts:Back

Shaolin Hong, Michael Campa, Sheila Lee, Elizabeth Gottlin, and Edward Patz
Protein biomarkers predict recurrence disease in patients with early stage non-small cell lung cancer
AACR Meeting Abstracts 2007 2007: LB-277.  

Qiang Zhang, Shilajit D Kundu, Thomas Jang, Michael Pins, Julie L Zhu, and Chung Lee
Transforming Growth Factor Beta 3 (TGF-β3) is a Potential Predictor of Prostate Cancer Aggressiveness
AACR Meeting Abstracts 2007 2007: LB-278.  

Moammir Aziz, Herbert Manoharan, Jordan Sand, Nancy Dreckschmidt, Soma Ray, Prakash Chinnaiyan, and Ajit Verma
PKC{epsilon} and Stat3, the proteins with oncogenic traits, universally interact with each other in their signals to induction, progression and invasion of human cancers
AACR Meeting Abstracts 2007 2007: LB-279.  

Angiogenesis inhibitors: Poster Presentations - Late-Breaking Abstracts:Back

Hyunkyung Yu, Inhwan Lim, Jinhyung Ahn, Hojeong Lee, Yangmi Lim, Jangseong Kim, and Yeup Yoon
Characterization of Anti-angiogenic Efficacies of Apo(a)-kringle V-Fc hybrid
AACR Meeting Abstracts 2007 2007: LB-281.  

Sonia Hernandez, Yasuhiro Funahashi, Indranil Das, Jianzhong Huang, Anshula Sharma, Akihiko Suzuki, Jessica Kandel, Jan Kitajewski, and Darrell Yamashiro
Notch blockade disrupts angiogenesis in a xenograft model of neuroblastoma
AACR Meeting Abstracts 2007 2007: LB-282.  

Angela Coxon, James Bready, Paul Hughes, Juan Estrada, Ling Wang, Thomas DeMelfi, Nicholas Doerr, Stephen Kaufman, Robert Radinsky, Richard Kendall, and Anthony Polverino
Motesanib diphosphate (AMG 706) inhibits the growth of medullary thyroid carcinoma in a nude mouse model
AACR Meeting Abstracts 2007 2007: LB-283.  

Anshu Roy, E. White, Lynn Rasmussen, Gary Piazza, Subramaniam Ananthan, Rongbao Li, and Zhican Qu
Screening for specific anti-angiogenic agents
AACR Meeting Abstracts 2007 2007: LB-284.  

Endothelial cell functions in vitro and in vivo: Poster Presentations - Late-Breaking Abstracts:Back

Jennifer Brown and Suparna Sanyal
Endothelial Cell Proliferation/Survival assay kit: a novel in vitro angiogenesis assay system
AACR Meeting Abstracts 2007 2007: LB-285.  

Host-tumor interactions: Poster Presentations - Late-Breaking Abstracts:Back

Kestutis Planutis, Marina Planutiene, and Randall Holcombe
Frizzled 1 inhibits cell proliferation and augments Wnt signal throughput in normal colon-derived cells without conferring additional sensitivity to exogenous Wnt3a ligand stimulation.
AACR Meeting Abstracts 2007 2007: LB-286.  

Stromal cells: Poster Presentations - Late-Breaking Abstracts:Back

Amorette Drexler, Cheryl Schaeberle, Carlos Sonnenschein, Ana Soto, and Maricel Maffini
The stroma holds the key to the mammary tumor resistance phenotype in Copenhagen rats
AACR Meeting Abstracts 2007 2007: LB-287.  

MMPs and TIMPs: Poster Presentations - Late-Breaking Abstracts:Back

Jennifer Przybylo, Alison Obr, and Derek Radisky
NF-kappaB mediates matrix metalloproteinase-induced EMT in mammary epithelial cells
AACR Meeting Abstracts 2007 2007: LB-288.  

Imaging in animal models: Poster Presentations - Late-Breaking Abstracts:Back

Neda Bajalo, P.N. Venkatasubramanian, Goo Lee, Rao Dirisina, David Shealy, Alice Wyrwicz, and Terrence Barrett
Magnetic resonance imaging accurately detects colitis-induced dysplasia and cancer and response to anti-TNF therapy.
AACR Meeting Abstracts 2007 2007: LB-290.  

New targets for imaging: Poster Presentations - Late-Breaking Abstracts:Back

Eugene Vykhovanets, Sanjeev Shukla, Gregory MacLennan, Martin Resnick, Harald Carlsen, Rune Blomhoff, and Sanjay Gupta
Molecular imaging of the transcription factor NF-kappaB during cytokine-induced intraprostatic inflammation
AACR Meeting Abstracts 2007 2007: LB-291.  

Application of imaging technology to the clinic: Poster Presentations - Late-Breaking Abstracts:Back

Joseph Nwankwo, Mary Wentworth, Marc Longino, Jamey Weichert, and Sharon Weber
Decreased PLD2 Expression Correlates with NM404 Retention in Human Colorectal Cancer Xenografts.
AACR Meeting Abstracts 2007 2007: LB-292.  

Intracellular Signaling 2: Poster Presentations:Back

Haifang Xu, Sharlene Washington, Michael Verderame, and Andrea Manni
Activation of protein kinase A (PKA) signaling mitigates the anti-invasive effect of DFMO in breast cancer cells
AACR Meeting Abstracts 2007 2007: 293.  

Subhas Chakrabarty, Guangming Liu, Xin Hu, and James Varani
Calcium enhances sensitivity to fluorouracil in colon carcinoma cells by modulating thymidylate synthase and survivin expression through the calcium sensing receptor
AACR Meeting Abstracts 2007 2007: 294.  

Charles Tindell, Michael Degtyarev, Kui Lin, and William Mallet
Transcriptional regulation of the prostate cancer antigen RA1c
AACR Meeting Abstracts 2007 2007: 295.  

Tisheeka Graham, Yuefang Wang, Haiyen Zhau, and Jonathan Simons
IGF-I activates genes in epithelial to mesenchymal transition in prostate cancer cells in vitro
AACR Meeting Abstracts 2007 2007: 296.  

Rozanne Arulanandam, Jun Cao, Adina Vultur, Reva Mohan, Richard Jove, Helene Feracci, and Leda Raptis
A novel pathway of Stat3 interaction with the Rho GTPases
AACR Meeting Abstracts 2007 2007: 297.  

anjali shukla, Yan Ho, Travis Friesen, Mariam Malik, Kwang Suh, and Stuart Yuspa
CLIC4 nuclear translocation, defective in tumor cells, enhances TGF-β signaling in association with the transcription factor Schnurri-2
AACR Meeting Abstracts 2007 2007: 298.  

Toru Kawamoto, Taro Okazaki, Hideo Suzuki, Ignacio Wistuba, Donghui Li, and Melanie Thomas
Signal Transducer and Activator of Transcription (STAT) 3 Expression in Gallbladder (GBC) and in Bile duct cancer (BDC) (Biliary tract cancer, BTC) : STAT 3 as a potential molecular target for BTC therapy
AACR Meeting Abstracts 2007 2007: 299.  

Valerie Hawthorne, Ling-Min Tseng, and Dihua Yu
Transcriptional upregulation of the p21Cip1 promoter by STAT3 and nuclear ErbB2
AACR Meeting Abstracts 2007 2007: 300.  

Xiaoyang Ling, Marina Konopleva, Zhihong Zeng, Vivian Ruvolo, L. Clifton Stephens, Wendy Schober, Teresa McQueen, Martin Dietrich, Timothy L. Madden, and Michael Andreeff
The novel triterpenoid CDDO-Me inhibits metastatic murine breast tumor through inhibition of Stat3 signaling
AACR Meeting Abstracts 2007 2007: 301.  

Miyakoshi masaaki, Hiroki Tanaka, Masahiro Yamamoto, Susumu Tamakawa, Masumi Yosie, Yoshihiko Tokusashi, Yuji Yaginuma, and Katsuhiro Ogawa
IL-6 promotes cell proliferation via JAK/STAT independent pathway in mouse hepatocellular carcinoma cells.
AACR Meeting Abstracts 2007 2007: 302.  

Reva Mohan, Rozanne Arulanandam, Adina Vultur, Ferruccio Galbiati, Ann Williams, Richard Jove, and Leda Raptis
Stat3 regulation by the caveolae protein, cav-1
AACR Meeting Abstracts 2007 2007: 303.  

Vivian Lui, Elaine Wong, Daisy Yau, Jennifer Grandis, and Anthony Chan
STAT3 targeting inhibits growth and invasion of nasopharyngeal cancer (NPC)
AACR Meeting Abstracts 2007 2007: 304.  

Ingrid Espinoza, Hong Liu, Lester Lau, and Ruth Lupu
The angiogenic factor CCN1: {alpha}6β1 integrin interaction: A key link in the estrogenic and antiestrogenic response in breast cancer cells
AACR Meeting Abstracts 2007 2007: 305.  

Hussein Al-Wadei, Maria Cekanova, Thomas Masi, Takashi Takahashi, and Hildegard Schuller
Cyclic AMP-mediated antagonistic effects of retinoids on lung cancers of different phenotype and cell lineage.
AACR Meeting Abstracts 2007 2007: 306.  

Jessica Faupel-Badger, Teresa Doucet, Erika Ginsburg, and Barbara Vonderhaar
The effects of anti-angiogenic 16 kDa prolactin expression in human breast cancer MDA-MB-435 cells
AACR Meeting Abstracts 2007 2007: 307.  

Gudmundur Thordarson, Laura Hernandez, Lucinda Jurden, and Sandra Macias
The effects of different mitogens on the proliferation of estrogen-dependent breast cancer cells after inactivation of the estrogen receptor
AACR Meeting Abstracts 2007 2007: 308.  

Dackour Raduwan, Yiding Chen, and Yuenian Shi
Tumor chaperone protein synuclein gamma stimulates membrane-bound 36kd ER-alpha signaling and renders tamoxifen resistance in breast cancers
AACR Meeting Abstracts 2007 2007: 309.  

Marina Ziche, Sandra Donnini, Federica Finetti, Raffaella Solito, Erika Terzuoli, Lucia Morbidelli, and Antonio Giachetti
EP2 prostanoid receptor promotes squamous cell carcinoma growth through EGFR transactivation and iNOS and ERK1/2 pathways
AACR Meeting Abstracts 2007 2007: 310.  

Arlee Fafalios, Ardavan Akhavan, Anil Parwani, and Beth Pflug
The role of translocator protein in prostate cancer
AACR Meeting Abstracts 2007 2007: 311.  

Lauren Cowell, Jessie Zhong, Jessica Smith, and Geraldine O'Neill
Estrogen receptor stimulation differentially regulates the stability of Cas family proteins p130Cas/BCAR1 and HEF1/Cas-L/NEDD9
AACR Meeting Abstracts 2007 2007: 312.  

Soo Ok Lee, Jae Yeon Chun, Wei Lou, and Allen Gao
Tumor necrosis factor alpha (TNF-{alpha}) activates androgen receptor (AR) in LNCaP prostate cancer cells
AACR Meeting Abstracts 2007 2007: 313.  

Minh Nguyen, Robert Harmon, and Zhou Wang
Identifying molecular factors in androgen receptor nucleocytoplasmic trafficking
AACR Meeting Abstracts 2007 2007: 314.  

yan hu, Soo OK Lee, Wei Lou, and Allen C. Gao
Down-regulation of IL-6 by selenium in the androgen-independent prostate cancer
AACR Meeting Abstracts 2007 2007: 315.  

Hong Cao, Alexandre Dimtchev, and Mira Jung
The regulation of ER alpha expression by chromatin modification
AACR Meeting Abstracts 2007 2007: 316.  

Thomas Johnson, Sweaty Koul, Sarah Venezia, and Hari Koul
Targeting extra-cellular signal -regulated kinase 1 and 2: A novel strategy for androgen independent prostate cancer
AACR Meeting Abstracts 2007 2007: 317.  

Maria Vias, Zoran Culig, David Neal, and Ian Mills
Neuroendocrine differentiation in anti-androgen resistant prostate cancer cells
AACR Meeting Abstracts 2007 2007: 318.  

Maria Veloso, Laura Todaro, Elisa Bal de Kier Joffe, and Lydia Puricelli
Effect of all trans retinoic acid (ATRA) on in vivo and in vitro growth of the murine lung tumor cell line LP07
AACR Meeting Abstracts 2007 2007: 319.  

Jason D'Antonio, Talal El-Hefnawy, Drazen Jukic, and Beth Pflug
Increased ETA receptor expression following androgen ablation therapy promotes prostate cancer cell survival and progression to advanced disease.
AACR Meeting Abstracts 2007 2007: 320.  

Dinesh Puppala, Hyosung Lee, Kyung Bo Kim, and Hollie Swanson
Degradation of AHR by PROTACS : A novel approach for cancer chemoprevention
AACR Meeting Abstracts 2007 2007: 321.  

Mourad Majidi, Hussein al-wadei, Takashi Takahashi, and Hildegard Schuller
Estrogen receptor beta enhances mitogenic signaling induced by the nicotine derived carcinogen NNK in human small airway epithelial cells
AACR Meeting Abstracts 2007 2007: 322.  

Preclinical pediatric research: Poster Presentations - Late-Breaking Abstracts:Back

Rachel Daniel, Agata Rozanska, Huw Thomas, Deborah Castelbuono, Alan Boddy, Deborah Tweddle, Nicola Curtin, and Steven Clifford
Preclinical evaluation of the poly-ADP ribose polymerase 1 (PARP-1) inhibitor AG014699 in combination with topotecan and temozolomide for the treatment of medulloblastoma and neuroblastoma
AACR Meeting Abstracts 2007 2007: LB-293.  

Susan Peirce, Donald Durden, Joseph Garlich, and Harry Findley
SF1126, a novel pan-PI3K inhibitor, inhibits activation of Mdm2 and increases sensitivity to doxorubicin in wild type p53 neuroblastoma cell lines
AACR Meeting Abstracts 2007 2007: LB-294.  

DNA damage and repair and mutagenesis: Poster Presentations - Late-Breaking Abstracts:Back

Joanna Albala, Christopher Bradley, Shey-Jen Shih, Andrew Vaughan, Danny Enepekides, and Gregory Farwell
Vitamin D-mediated inhibition of Rad51 expression in head and neck squamous cell carcinoma.
AACR Meeting Abstracts 2007 2007: LB-295.  

Photobiology/photodynamic therapy: Poster Presentations - Late-Breaking Abstracts:Back

Jean Starkey, Aleksander Rebane, Mikhail Drobijev, Aliesha Elliott, Fanquing Meng, Aijun Gong, and Charles Spangler
Novel NIR PDT sensitizers lead to regressions of human lung tumor xenografts when laser activated through the body of host SCID mice.
AACR Meeting Abstracts 2007 2007: LB-296.  

Drug design: Poster Presentations - Late-Breaking Abstracts:Back

Jack Youngren, Joseph Blecha, Marc Anderson, Jennifer Chow, Christle Guevarra, Celia Pender, Cristina Penaranda, Stefanie Ng, Marianna Zavodovskaya, Michael Campbell, and Clifford Berkman
Inhibition of IGF-1 receptor and alternate cancer targets by nordihydroguaiaretic acid (NDGA) analogs
AACR Meeting Abstracts 2007 2007: LB-298.  

Athanasia Katsoulas, Zakaria Rachid, James McNamee, and Bertrand Jean-Claude
The combi-targeting concept: an optimized single-molecule dual-targeting model for the treatment of Chronic Myelogenous Leukemia
AACR Meeting Abstracts 2007 2007: LB-299.  

Natural products: Poster Presentations - Late-Breaking Abstracts:Back

Peter McDonald, Thomas Graham, Peter Wipf, and John Lazo
Profiling genes and networks regulating the cytotoxicity of the marine natural product disorazole C1
AACR Meeting Abstracts 2007 2007: LB-300.  

Chemotherapy-Related Cognitive Dysfunction: Oral Presentations - Invited Abstracts:Back

Patricia Ganz
Clinical manifestations of cognitive dysfunction in patients receiving chemotherapy
AACR Meeting Abstracts 2007 2007: SS03-01.  

Metastasis: Oral Presentations - Invited Abstracts:Back

David Lyden
The pre-metastatic Niche: A Novel Predictor of Metastasis
AACR Meeting Abstracts 2007 2007: SY03-01.  

Joan Massague
Genes that couple breast cancer tumor growth and lung metastasis
AACR Meeting Abstracts 2007 2007: SY03-02.  

High throughput screening (assays and libraries): Poster Presentations - Late-Breaking Abstracts:Back

Kamalika Moulick, Yuhong Du, Julia Aguirre, Sara Felts, Raymond Dingledine, Haian Fu, and Gabriela Chiosis
High-throughput screening fluorescence polarization assay for tumor-specific Hsp90
AACR Meeting Abstracts 2007 2007: LB-301.  

Synthesis: Poster Presentations - Late-Breaking Abstracts:Back

Michael Hay, Ho Lee, Shangjin Yang, Kevin Hicks, Bronwyn Siim, Frederik Pruijn, William Wilson, and William Denny
The development of an efficient, scalable synthesis of the hypoxia-selective cytotoxin SN 30000
AACR Meeting Abstracts 2007 2007: LB-302.  

Drug delivery: Poster Presentations - Late-Breaking Abstracts:Back

Changping Zou, Chun Li, Xianyi Cao, Jean Feugang, Jianxin Lin, Rongyu Zang, Yuanjian Deng, Chusilp Charnsangavej, and Molly Brewer
Antitumor activity of 4-(N-Hydroxyphenyl) Retinamide conjugated with Poly(L-Glutamic Acid) against ovarian cancer xenografts
AACR Meeting Abstracts 2007 2007: LB-303.  

Other biophysical methods: Poster Presentations - Late-Breaking Abstracts:Back

Francis Martin, Xinhui Bi, Michael Walsh, Xiaomin Wei, Pierre Martin-Hirsch, Guoying Sheng, Jiamo Fu, Gareth Thomas, and Kevin Jones
Infrared spectral analysis of MCF-7 cells treated with serum-lipid extracts of Chinese origin segregates predominantly brominated flame retardant-exposed subjects from those with mainly organochlorine exposures
AACR Meeting Abstracts 2007 2007: LB-304.  

Proteomic analysis: Poster Presentations - Late-Breaking Abstracts:Back

Zhen Xiao, Lidia Hernandez, Timothy Veenstra, and Colin Stewart
Analysis of the extracellular matrix proteome by mass spectrometry
AACR Meeting Abstracts 2007 2007: LB-306.  

Douangsone Vadysirisack, Zhaoxia Zhang, Ming-Daw Tsai, and Sissy Jhiang
Identification of Na+/I- symporter phosphorylation sites and their biological significance
AACR Meeting Abstracts 2007 2007: LB-307.  

Combination chemotherapy: Poster Presentations - Late-Breaking Abstracts:Back

Takayuki Ikezoe, Chie Nishioka, Ayuko Taniguchi, Yoshio Kuwayama, Naoki Komatsu, Kentaro Bandobashi, Kazuto Togitani, H Koeffler, and Hirokuni Taguchi
ZD6474 induces growth arrest and apoptosis of human leukemia cells, which is enhanced by concomitant use of a novel MEK inhibitor, AZD6244
AACR Meeting Abstracts 2007 2007: LB-309.  

Mor-Li Hartman, John Esposito, Beow Yeap, and David Sugarbaker
Rapamycin increases sensitivity to cisplatin in mesothelioma cell lines
AACR Meeting Abstracts 2007 2007: LB-310.  

Stephanie DECOLLOGNE and Philip Hogg
The mitochondrial poison GSAO in combination with gemcitabine suppresses growth of human pancreatic carcinoma xenografts in nude mice
AACR Meeting Abstracts 2007 2007: LB-311.  

Stephen Parsons, Ann McNulty, Bruce Konicek, Rebecca Lynch, Andrew Capen, Phil Schwier, Robin Goode, James Starling, and Jeremy Graff
Enzastaurin (LY317615.HCl) dramatically enhances sensitivity to temozolomide in glioblastomas, blocking pro-survival signaling and CREB transcription factor activation
AACR Meeting Abstracts 2007 2007: LB-312.  

Mukur Gupta, Derrick Barnes, Jan Losos, Glenn Spehar, Mark Bednarcik, and William Peters
Anti-tumor activity of ADH-1 in vitro and in vivo in combination with paclitaxel in ovarian cancer cell lines
AACR Meeting Abstracts 2007 2007: LB-356.  

New targets: Poster Presentations - Late-Breaking Abstracts:Back

Ruben Gonzalez, Salandre Cherfils, Moshood Olatinwo, Daina Ngugi, Manuel Penichet, and Bo Rueda
Leptin signaling inhibition: A novel target for breast cancer prevention and treatment.
AACR Meeting Abstracts 2007 2007: LB-313.  

Identification of molecular targets: Poster Presentations - Late-Breaking Abstracts:Back

shilpi arora, Eileen Adamson, Yipeng Wang, Michael McClelland, and Dan Mercola
Identification of Egr1 target genes in prostate cancer cells upon UV stimulation using promoter arrays
AACR Meeting Abstracts 2007 2007: LB-314.  

Stanley Nwokenkwo, Caroline Diep, Michael Barret, Steven Warner, Manuel Hidalgo, Haiyong Han, and Daniel Von Hoff
Microtuble-associated TPX2 is amplified in pancreatic cancer
AACR Meeting Abstracts 2007 2007: LB-315.  

Cell death pathways and treatment: Poster Presentations - Late-Breaking Abstracts:Back

Peter Ebeling, Phil Kearney, Jan Duerig, Thomas Moritz, Bo Hansen, and Margit Wissenbach
SPC2996, a novel mRNA antagonist targeting Bcl-2, is therapeutically active in a preclinical model of human chronic lymphocytic leukemia
AACR Meeting Abstracts 2007 2007: LB-316.  

Avi Ashkenazi, Cam Adams, Klara Totpal, Laura Deforge, David Lawrence, Sharon Yee, Sarajane Ross, Roger Pai, Authur Reyes, Christina deZafra, Hong Xiang, and Christopher Stebbins
Anti-tumor activity of Apomab: a fully human agonistic monoclonal antibody that targets the pro-apoptotic receptor DR5
AACR Meeting Abstracts 2007 2007: LB-317.  

New in vitro and in vivo models for targets: Poster Presentations - Late-Breaking Abstracts:Back

Huynh Hung, Patrick Tan, Nallasivam Palanisamy, Manual Salto-Tellez, Boon Goh, Khee Soo, Puay Tan, Richie Soong, Han Toh, and Pierce Chow
Effective inhibition of tumor growth in patient-derived xenografts of hepatocellular carcinoma by rapamycin and bevacizumab
AACR Meeting Abstracts 2007 2007: LB-318.  

Bin Yin, Miechaleen Diers, Susan Rathe, Shannon Delaney, M. Dolan, Scott Lowe, and David Largaespada1
Genetic dissection of chemoresistance mechanisms and development of reverse strategy in leukemia using cell culture and mouse transplantation models
AACR Meeting Abstracts 2007 2007: LB-319.  

Non-P-glycoprotein multidrug resistance: Poster Presentations - Late-Breaking Abstracts:Back

Paiboon Jungsuwadee, Yumin Chen, Ramaneeya Nithipongvanitch, Jitbanjong Tangpong, Terry Oberley, D Allan Butterfield, Daret St.Clair, and Mary Vore
Mrp1 localization in cardiac mitochondria and inactivation of its transport activity following doxorubicin in mice
AACR Meeting Abstracts 2007 2007: LB-320.  

Reversal of drug resistance: Poster Presentations - Late-Breaking Abstracts:Back

Toshiyuki Kozuki, Nagio Takigawa, Masami Takeyama, Takuo Shibayama, Akiko Hisamoto, Katsuyuki Kiura, Atsuhiko Tada, Masahiro Tabata, Mitsune Tanimoto, and Kiyoshi Takahashi
Combination of SN-38 with gefitinib or imatinib overcomes SN-38-resistant small-cell lung cancer cells
AACR Meeting Abstracts 2007 2007: LB-321.  

Takashi Kagami, Yuwei Wang, Amy Tien, Akira Watahiki, Maisie Lo, Hui Xue, Peter Gout, and Yu-Zhuo Wang
Sulfasalazine enhances growth-inhibitory activity of doxorubicin: Potential use in combination chemotherapy of advanced prostate cancer
AACR Meeting Abstracts 2007 2007: LB-322.  

Hong Liu, Javier Menendez, and Ruth Lupu
Hyperforin, a major lipophilic constituent of St. John's wort, enhances paclitaxel sensitivity in HER2 overexpressing breast cancer cells.
AACR Meeting Abstracts 2007 2007: LB-323.  

Intracellular Signaling 3: Poster Presentations:Back

Yan Ding, Elissa Boguslawski, Bree Berghuis, John Young, Zhongfa Zhang, and Nicholas Duesbery
MKK signaling is required for fibrosarcoma growth and vascularization.
AACR Meeting Abstracts 2007 2007: 323.  

Audrey Sirvent, Anthony Boureux, Valerie Simon, and Serge Roche
The tyrosine kinase Abl is requiered for Src-induced cell transformation implicating Rac and ERK5 pathways
AACR Meeting Abstracts 2007 2007: 324.  

Keiran Smalley, Rooha Contractor, C. Angelica Medina, Katherine Nathanson, and Meenhard Herlyn
Identification of melanoma cells with resistance to BRAF and MEK inhibitors
AACR Meeting Abstracts 2007 2007: 325.  

Valeria Grossoni, Juan Karlic, Marcelo Kazanietz, Elisa Bal de Kier Joffe, and Alejandro Urtreger
The MEK/ERK and PI3K/AKT signalling pathways modulate cell growth and apoptosis resistance induced by PKC{delta} overexpression in normal murine mammary cells
AACR Meeting Abstracts 2007 2007: 326.  

Neale Hanke and G. Bowden
Loss of catalase elevates stress activated MAPK pathways in mouse keratinocyte tumor progression
AACR Meeting Abstracts 2007 2007: 327.  

Leah Lyons, Shuyun Rao, Wayne Balkan, and Kerry Burnstein
Oncogenic Vav3 promotes ligand-independent androgen receptor activation via Rho GTPase signaling: a mechanism of androgen-independent prostate cancer progression
AACR Meeting Abstracts 2007 2007: 328.  

Christoph-Erik Mayer, Barbara Haigl, Slav Ovtcharov, Michael Micksche, Walter Berger, and Hedwig Sutterluty
Sprouty expression is regulated by multiple mechanisms: How are they altered in cancer?
AACR Meeting Abstracts 2007 2007: 329.  

Line Myklebust, Bodil Bjorndal, Ken Rosendal, Froydis Myromslien, James Lorens, Garry Nolan, Ove Bruland, and Johan Lillehaug
Ki-Ras-mediated signaling and morphological transformation of NIH 3T3 cells is regulated by RACK1
AACR Meeting Abstracts 2007 2007: 330.  

Robert Nichols, Linda deGraffenried, and LuZhe Sun
The role of ERK in the crosstalk between Smad4 and ER{alpha} signaling in ER{alpha} positive breast carcinoma cells
AACR Meeting Abstracts 2007 2007: 331.  

Ada Roxana Girnita, Leonard Girnita, and Olle Larsson
Synergistic effects of estrogens and IGF-1 on ERK signaling in breast cancer cells
AACR Meeting Abstracts 2007 2007: 332.  

Qingding Wang, Yunning Zhou, and B. Evers
Neurotensin stimulates COX-2/PGE2 production in HT29 human colon cancer cells through p38/MAPK activation
AACR Meeting Abstracts 2007 2007: 333.  

Andrea Manni, Sharlene Washington, Xin Hu, Michael Verderame, and Haifang Xu
Role of non-receptor and receptor tyrosine kinases (TK) in the antitumor action of {alpha}-difluoromethylornithine (DFMO) in breast cancer cells
AACR Meeting Abstracts 2007 2007: 334.  

Richard Morgan, Benjamin Fairfax, and Hardev Pandha
p38 MAPK and calcium sensitivity in pancreatic cancer
AACR Meeting Abstracts 2007 2007: 335.  

Debora Meira, Isabel Nobrega, Janio Mororo, Vitor Hugo Almeida, Lucia Bardella, Everardo Saad, Ricardo Silva, Rodolpho Albano, and Carlos Ferreira
Differences in activity between matuzumab and cetuximab in A431 cells may rely on MAPK cascade inhibition
AACR Meeting Abstracts 2007 2007: 336.  

Richard Cutler, Brett Garrick, Eun Ok Kim, Leanne Goon, Peiwen Yu, Stuart Johnston, and Timothy Heuer
Comparative analysis of Raf inhibition versus MEK inhibition in Ras driven tumor cell lines
AACR Meeting Abstracts 2007 2007: 337.  

Leonard Girnita, Ada Girnita, and Olle Larsson
β-arrestin and Mdm2 mediate IGF-1 receptor signalling
AACR Meeting Abstracts 2007 2007: 338.  

Chengfeng Yang, Eric Klein, Richard Assoian, and Marcelo Kazanietz
p21Cip1 is a critical mitogenic factor for heregulin β1 (HRG)-induced breast cancer cell proliferation
AACR Meeting Abstracts 2007 2007: 339.  

Mike Burbridge, Livio Trusolino, Andrea Bertotti, Martina Maurer, Caroline Sanglier, Agnes Chomel, Sabrina Hersant, Gaelle Rolland-Valognes, Jean-Pierre Galizzi, Brian Lockhart, Heinz Fiebig, John Hickman, and Paolo Comoglio
Phosphoproteomic profiling of Met tyrosine kinase inhibition
AACR Meeting Abstracts 2007 2007: 340.  

Taranjit Gujral, Douglas Richardson, Shirley Myers, Mireia Dunach, and Lois Mulligan
The RET receptor tyrosine kinase causes activation of the β-catenin pathway
AACR Meeting Abstracts 2007 2007: 341.  

Weiping Zhang, Shailaja Kalyankrishna, Chao Cui, William Gooding, Jennifer Hunt, Jennifer Grandis, and Jill Siegfried
Bradykinin initiates EGFR transactivation and MAPK phosphorylation resulting in cyclooxygenase2 induction via the B2 receptor in HNSCC
AACR Meeting Abstracts 2007 2007: 342.  

Jingrui Jiang and James Griffin
Activation of beta-catenin by mutant FLT3 receptors is mediated by GSK3-beta
AACR Meeting Abstracts 2007 2007: 343.  

Ke Liang, Yang Lu, xinqun Li, Yong Li, Constance Albarracin, and Zhen Fan
Erythropoietin-induced cell signaling confers HER2-overexpressing breast cancer cells resistance to trastuzumab treatment
AACR Meeting Abstracts 2007 2007: 344.  

Li Xu, Monique Nilsson, Emer Hanrahan, Tina Cascone, Yanan Yang, jonathan kurie, Danny Du, Ignacio Wistuba, Ludmila Prudkin, Diane Liu, Jeffrey Engelman, Faye Johnson, and John Heymach
Activated EGFR regulates invasiveness of non-small cell lung cancer cells through HIF-1{alpha} mediated Met expression
AACR Meeting Abstracts 2007 2007: 345.  

Rishu Takimoto, Koichi Takada, Ganji Kuroiwa, Tomoki Fujita, Junji Kato, and Yoshiro Niitsu
Significance of protein phosphatase 2A as a tumor suppressor in TGF-beta signaling pathway
AACR Meeting Abstracts 2007 2007: 346.  

Munenori Takaoka, Seok-Hyun Kim, James Lee, Carmen Michaylira, Doug Stairs, Takaomi Okawa, Claudia Andl, Cameron Johnstone, Ben Rhoades, Andres Klein-Szanto, Wafik El-Deiry, Volker Haase, and Hiroshi Nakagawa
Insulin-like growth factor binding protein-3, induced by hypoxia inducible factor-1{alpha}, determines esophageal cancer cell adaptation to the microenvironment
AACR Meeting Abstracts 2007 2007: 347.  

Kristi Baker, Pooja Raut, and Jeremy Jass
TGFβRII mutation does not abrogate autocrine TGFβ signaling in mismatch repair deficient colorectal cancers
AACR Meeting Abstracts 2007 2007: 348.  

Shouwei Han, Ying Zheng, Jeff Ritzenthaler, and Jesse Roman
Prostaglandin E2 (PGE2) stimulates the proliferation of human lung carcinoma cells through activation of ILK: the involvement of PGE2 receptor subtype EP4
AACR Meeting Abstracts 2007 2007: 349.  

Karanjodh Johal, Jaesung Woo, Calista Santoso, Joseph Hanson, Christopher Hope, Kestutis Planutis, and Randall Holcombe
Low dose resveratrol inhibits Wnt signaling proximal to β-catenin
AACR Meeting Abstracts 2007 2007: 350.  

Christopher Gubish, Laura Stabile, Mary Rothstein, and Jill Siegfried
Interaction between the COX-2 pathway and HGF/c-Met pathway in non-small cell lung cancer
AACR Meeting Abstracts 2007 2007: 351.  

Sudhakar Akulapalli, Chandra Shekhar Boosani, Dominic Cosgrove, and Christopher Overall
Integrin and non-integrin mediated signaling mechanisms of {alpha}1(IV)NC1
AACR Meeting Abstracts 2007 2007: 352.  

Alkylating agents: Poster Presentations - Late-Breaking Abstracts:Back

Daniel Wu, Bo Cui, Stewart Johnson, Stephen Keir, Jill Maxwell, Darell Bigner, and Henry Friedman
Mechanisms of Temozolomide resistance in pediatric glioblastoma multiforme
AACR Meeting Abstracts 2007 2007: LB-324.  

Novel antitumor agents: Poster Presentations - Late-Breaking Abstracts:Back

Moulay. Alaoui-Jamali, Liren Tang, Genhui Chen, Bin Li, Michael Lyle, and John Webster
Insight into the biological activity of a naturally-derived dithiopyrrolone with a wide spectrum activity against metastatic cancer models
AACR Meeting Abstracts 2007 2007: LB-325.  

Alison Maloney, Paul Clarke, Soren Naaby-Hansen, Rob Stein, Jens-Oliver Koopman, Akunna Akpan, Alice Yang, Markta Zvelbil, Rainer Cramer, Lindsay Stimson, Wynne Aherne, Udai Banerji, Ian Judson, Swee Sharp, Marissa Powers, Emmanuel DeBilly, Joanne Salmons, Michael Walton, Al Burlinghame, Michael Waterfield, and Paul Workman
mRNA and protein expression profiling highlights modulation of chromatin-related proteins and chromatin-modifying enzymes in response to HSP90 inhibitors: Identification of PRMT5 as a novel client protein.
AACR Meeting Abstracts 2007 2007: LB-326.  

HDAC and methyltransferase inhibitors: Poster Presentations - Late-Breaking Abstracts:Back

James Symanowski, Yvonne Giraud, Pamela Dino, Peter Atadja, Nicholas Vogelzang, and Sunil Sharma
Synergistic interaction between histone deacetylase (HDAC) inhibitor LBH589 and Cisplatin (CDDP) in mesothelioma cell lines
AACR Meeting Abstracts 2007 2007: LB-327.  

Tubulin agents: Poster Presentations - Late-Breaking Abstracts:Back

Erwan Jouannot, Chantal Carrez, Nathalie Lassau, Pascale Lejeune, Brigitte Demers, Patricia Vrignaud, and Marie-Christine Bissery
Demonstration in animal and human of AVE8062-induced tumor blood flow shutdown using dynamic contrast enhanced-ultrasonography (DCE-US).
AACR Meeting Abstracts 2007 2007: LB-328.  

Tyrosine kinase and phosphatase inhibitors: Poster Presentations - Late-Breaking Abstracts:Back

Issan Tam, Lai Leung, Lap Chung, and Maria Wong
EGFR with L858R and H870R double mutations showed reduced sensitivity to Gefitinib
AACR Meeting Abstracts 2007 2007: LB-329.  

Lisa O' Connor, Steven Langabeer, Eibhlin Conneally, and Shaun McCann
Determining the mutational status of the BCR-ABL kinase domain in Chronic Myeloid Leukaemia patients with resistance to the tyrosine kinase inhibitor Imatinib Mesylate
AACR Meeting Abstracts 2007 2007: LB-330.  

Apoptosis: therapeutic manipulation: Poster Presentations - Late-Breaking Abstracts:Back

Peter Simon, Jonathon McDunn, Hiroyuki Kashiwagi, Peter Goedegeburre, Katherine Chang, Richard Hotchkiss, and William Hawkins
Targeting the akt pathway with the pro-apoptotic peptide, Tat-CTMP: a novel strategy for the treatment of pancreatic adenocarcinoma
AACR Meeting Abstracts 2007 2007: LB-331.  

Katherine Aird, Xiuyun Ding, Aris Baras, Junping Wei, Timothy Clay, Herbert Lyerly, and Gayathri Devi
Targeting the anti-apoptotic activity of XIAP inhibits inflammatory breast cancer cells and overcomes Trastuzumab resistance
AACR Meeting Abstracts 2007 2007: LB-332.  

Growth factor receptors and other surface antigens as targets for therapy: Poster Presentations - Late-Breaking Abstracts:Back

Hiroshi Kitagawa, Keiki Sugimoto, Hidenori Kage, Atsushi Sano, Naomi Aki, Takahide Nagase, Nobuya Ohishi, and Daiya Takai
Synergism of Akt, ERK, or STAT3 inhibitors on gefitinib in lung adenocarcinoma cell lines.
AACR Meeting Abstracts 2007 2007: LB-333.  

Oncogenes, tumor suppressor genes, and gene products as targets for therapy: Poster Presentations - Late-Breaking Abstracts:Back

Altaf Dar, Abbes Belkhiri, Maria Blanca Piazuelo, DunFa Peng, Pelayo Correa, Tatsuki Koyama, Antoni Castellas, Kay Washington, Alexander Zaika, Robert Coffee, and Wael El-Rifai
The Molecular and Biological Significance of Aurora Kinase A Overexpression in Upper Gastrointestinal Adenocarcinomas
AACR Meeting Abstracts 2007 2007: LB-334.  

Jozsef Timar, Istvan Kenessey, Livia Meszaros, Attila Adam, Jozsef Tovari, and Erzsebet Raso
Mutant EGFR in human melanoma and its preclinical targeting
AACR Meeting Abstracts 2007 2007: LB-335.  

Cancer vaccines: Poster Presentations - Late-Breaking Abstracts:Back

Gang Li, Samita Andreansky, Xinchun Chen, Manuel Penichet, and Emmanuel Katsanis
Tumor-derived Chaperone-Rich Cell Lysate Generates HER-2/neu Specific Immunity in a Mouse Model of Breast Cancer
AACR Meeting Abstracts 2007 2007: LB-337.  

Specific immunomechanisms: Poster Presentations - Late-Breaking Abstracts:Back

Seongwon Choi, Hyun Ho Choi, Sun-Hye Lee, and Myung-Hee Chung
Anti-inflammatory Effect of 8-Hydroxy-2'-deoxyguanosine via Rac Auppression in Balb/c Mice.
AACR Meeting Abstracts 2007 2007: LB-338.  

Adrian Bot, Kent Smith, Victor Tam, Xiping Liu, Robb Pagarigan, Brenna Meisenburg, Diljeet Joea, Raymond Wong, Christiana Sanders, David Diamond, Zhiyong Qiu, Diane Da Silva, Martin Kast, and Thomas Kuendig
DNA vaccination revisited: induction of potent immunity by sequential injection of lymph nodes with plasmid vectors and peptides
AACR Meeting Abstracts 2007 2007: LB-339.  

RAJENDRA DAMLE, Sonal Temburni, Taraneh Banapour, Steven Allen, Kanti Rai, and Nicholas Chiorazzi
Evidence for a CD38+ active subset enriched in proliferating cells, within the clonal population in chronic lymphocytic leukemia patients
AACR Meeting Abstracts 2007 2007: LB-340.  

Jennifer Luth and Breton Barrier
CD28 and ICOS expression in human ovarian carcinoma cells
AACR Meeting Abstracts 2007 2007: LB-341.  

Phase I Clinical Trial Data: Poster Presentations - Late-Breaking Abstracts:Back

Michael Pollak, P Eisenberg, D Karp, R Cohen, H Kreisman, A Adjei, C Langer, C. Melvin, D Yin, and A Gualberto
Safety and tolerability of the anti-IGF-I receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in patients with advanced solid tumors
AACR Meeting Abstracts 2007 2007: LB-343.  

Robert Prins, Sylvia Odesa, Horacio Soto, Meng-Yin Yang, Likhith Alakandy, Haumith Khan-Farooqi, Marnix Bosch, Alton Boynton, Tim Cloughesy, and Linda Liau
Dendritic cell vaccination in combination with the TLR7/8 agonist, imiquimod, following radiotherapy and concomitant chemotherapy for newly diagnosed glioblastoma
AACR Meeting Abstracts 2007 2007: LB-346.  

Charles Lu, Carmen Sepulveda, Lin Ji, Rajagopal Ramesh, Sean O'Connor, Gitanjali Jayachandran, Marshall Hicks, Reginald Munden, J. Lee, Nancy Templeton, John McMannis, and Jack Roth
Systemic therapy with tumor suppressor FUS1-nanoparticles for stage IV lung cancer
AACR Meeting Abstracts 2007 2007: LB-348.  

Panos Savvides, A Argiris, J Greskovich, J Bokar, C Hoppel, R Rezaee, P Fu, J Wasman, P Lavertu, and S Remick
Phase I study of the EGFR tyrosine kinase inhibitor erlotinib in combination with docetaxel and radiation in locally advanced squamous cell cancer of the head and neck (SCCHN)
AACR Meeting Abstracts 2007 2007: LB-350.  

Navneet Dhillon, Stacy Moulder, David Hong, Chaan Ng, Luis Camacho, Evan Hersh, Kathryn Grenier, Robert Dorr, and Razelle Kurzrock
Phase I trial of imexon and docetaxel in patients with previously-treated stage IV non-small cell lung cancer, metastatic breast cancer or hormone-refractory prostate cancer.
AACR Meeting Abstracts 2007 2007: LB-351.  

Pamela Munster, Douglas Marchion, Elona Bicaku, Morgen Schmitt, Mira Lacevic, Bradford Carter, Charles Cox, and Adil Daud
Feasibility and efficacy of valproic acid as a histone deacetylase inhibitor to potentiate anthracyclines: A phase I and pilot study in locally advanced/metastatic breast cancer.
AACR Meeting Abstracts 2007 2007: LB-353.  

Immunotherapy of human cancer/human clinical trials: Poster Presentations - Late-Breaking Abstracts:Back

Alessandro Santin, Stefania Bellone, Michela Palmieri, Alessandro Zanolini, Antonella Ravaggi, Eric Siegel, Juan Roman, Alexander Burnett, Sergio Pecorelli, and Martin Cannon
Human Papillomavirus 16/18 E7-Pulsed Dendritic Cell Vaccination in Stage IB-IIA Cervical Cancer Patients; A Phase I Escalating Dose Trial
AACR Meeting Abstracts 2007 2007: LB-344.  

Pharmacogenetics/genomics and therapeutic responses: Poster Presentations - Late-Breaking Abstracts:Back

Zhimin Guo, Sarah Oakes, Yingnian Lu, Michio Sugita, Wilbur Franklin, and Alex Franzusoff
Oncogenic Synergy and a Newly Identified Transforming Ras Mutation in Human Cancer
AACR Meeting Abstracts 2007 2007: LB-345.  

Andres Cervantes, Fortunato Ciardiello, Fernando Rivera, Federico Rojo, Esther Casado, Edith Rodriguez-Braun, Erika Martinelli, Oliver Kisker, Jose Baselga, and Josep Tabernero
Optimal dose of cetuximab administered every 2 weeks (q2w): A phase I safety, pharmacokinetics (PK) and pharmacodynamics (PD) study of weekly (q1w) and q2w schedules in patients (pts) with metastatic colorectal cancer (mCRC)
AACR Meeting Abstracts 2007 2007: LB-352.  

Molecular Genetics 1: Poster Presentations:Back

Ceshi Chen, Zhongmei Zhou, Wei Zhou, Jin-Tang Dong, and Arun Seth
The WWP1 E3 ubiquitin ligase: A potential molecular target for breast cancer
AACR Meeting Abstracts 2007 2007: 353.  

Abbas Shakoori
Computer-aided scoring and analysis of immunohistochemistry staining using lung tissue microarray
AACR Meeting Abstracts 2007 2007: 354.  

Anjan Misra, Ivan Smirnov, Marcus Ware, Chibo Hong, Yuichi Hirose, Ezra Mirvish, Leon Kapp, Samir Kharbanda, Janice Nigro, Edward Pan, Lars Prestagarden, Ru-Fung Yeh, Joseph Costello, Allan Yates, Dannis Pearl, Berndt Scheithauer, Catarina Gianinni, Peter Burger, Heidi Phillips, Ken Aldape, and Burt Feuerstein
PTEN copy number is a better marker for survival than histologic grade in consensus grade 2 and 3 astrocytomas
AACR Meeting Abstracts 2007 2007: 355.  

Mamatha Shekar, Ramesh Ramakrishnan, and Robert Jones
A nanofluidic system capable of rapid, reliable and cost-effective genotyping
AACR Meeting Abstracts 2007 2007: 356.  

Sheryl Gough, Alan Aitchison, Peter Ganly, Ruth Spearing, and Christine Morris
Hs.568769 is disrupted by a novel t(5;10) in acute lymphoblastic leukemia (ALL) and may be an alternate transcript of the 3'overlapping DNTT (TdT) gene
AACR Meeting Abstracts 2007 2007: 357.  

Ramasamy Jagadeeswaran, Hanna Surawska, Soundararajan Krishnaswamy, Varalakshmi Janamanchi, A Mackinnon, Tanguy Seiwert, Sivakumar Loganathan, Rajani Kanteti, Trevor Reichman, Vidya Nallasura, Maria Tritiakova, Salman Ahmed, Osvaldo Zumba, Lioubov Soulii, Vytas Bindokas, Livya Szeto, Mark Lingen, Thomas Krausz, Wickii Vigneswaran, Viswanathan Natarajan, Everett Vokes, Mark Ferguson, Aliya Hussain, and Ravi Salgia
The focal adhesion paxillin is a target for somatic mutations in lung cancer: implications for enhanced cell growth and invasion
AACR Meeting Abstracts 2007 2007: 358.  

Santanu Dasgupta, Elizabeth Mambo, Mohammad Obaidul Hoque, Aditi Chatterjee, Sunil Upadhyay, and David Sidransky
Mitochondria encoded Cytochrome B gene mutation contributes to enhanced tumor growth in bladder cancer
AACR Meeting Abstracts 2007 2007: 359.  

Hung-Wei Pan, Shian-Yang Peng, Chao-Lien Liu, and Hey-Chi Hsu
L2DTL encodes a nuclear and centrosome protein and its overxpression correlates with aggressive hepatocellular carcinoma
AACR Meeting Abstracts 2007 2007: 360.  

Karin Birkenkamp-Demtroeder, Francisco Mansilla, Mogens Kruhoffer, Flemming Soerensen, Lise Lotte Christensen, Lauri Aaltonen, Hein Verspaget, and Torben Orntoft
A novel phosphoprotein accumulating in MSS but not MSI human colorectal cancers impacts cell proliferation and viability in vitro
AACR Meeting Abstracts 2007 2007: 361.  

Lai Rai-Hua, Mei-Jung Wang, Chew-Wun Wu, Ya-Wen Hsiao, Chin-Wen Chi, Anna Fen-Yau Li, Shung-Haur Yang, Yuh-Shan Jou, and Jeou-Yuan Chen
SOCS6 suppresses cell growth and is frequently inactivated in human gastrointestinal cancers
AACR Meeting Abstracts 2007 2007: 362.  

Sarina Sulong, Julie Irving, Marian Case, Lynne Minto, Nick Bown, Simon Bailey, Christine Harrison, and Andrew Hall
Determination of chromosomal structural changes in childhood acute lymphoblastic leukemia using high-density SNP arrays
AACR Meeting Abstracts 2007 2007: 363.  

Xiang Ling, Jennifer D. Black, and Fengzhi Li
An unexpected mechanism by which the proapoptotic factor survivin-2B abrogates mitotic cells and induces mitochondria-dependent apoptosis
AACR Meeting Abstracts 2007 2007: 364.  

Tomasz Wojdacz, Ee Ming Wong, Michael Krypuy, and Alexander Dobrovic
High resolution melting allows sensitive high-throughput assessment of methylation in tumour samples.
AACR Meeting Abstracts 2007 2007: 365.  

Weimin Gao, Yang Liu, Jill Siegfried, Neil Christie, Autumn Gaither-Davis, James Luketich, and Phouthone Keohavong
K-ras, p53 mutations and p16 promoter methylation in bronchoscopy samples from former lung cancer patients
AACR Meeting Abstracts 2007 2007: 366.  

Shian-ling Ding, Jyh-Cherng Yu, Shou-Tung Chen, Giu-Cheng Hsu, and Chen-Yang Shen
Genetic variation in the premature aging gene, WRN: a case-control study on breast cancer susceptibility
AACR Meeting Abstracts 2007 2007: 367.  

Alexander Baras, Pat Pramoonjago, Michael Filtz, and Christopher Moskaluk
Identification of potential secreted protein biomarkers in human squamous cell carcinoma
AACR Meeting Abstracts 2007 2007: 368.  

Francisco Mansilla, Shuli Wang, Kerry-Ann Da Costa, Mogens Kruhoffer, Torben Orntoft, Rosalind Coleman, and Karin Birkenkamp-Demtroder
Overexpression of a novel human lysophosphatidylcholine acyltransferase in colorectal cancer and its role in lipid metabolism
AACR Meeting Abstracts 2007 2007: 369.  

Yuria Mano, Yataro Daigo, Koji Takahashi, Atsushi Takano, Eiju Tsuchiya, and Yusuke Nakamura
Identification of LAPLD as a novel therapeutic target oncogene in lung carcinogenesis
AACR Meeting Abstracts 2007 2007: 370.  

Albert Dobi, Gyorgy Petrovics, Jennifer Cullen, Bungo Furusato, Lakshmi Ravindranath, Christopher Cook, Yongmei Chen, ChunLing Gao, Isabell Sesterhenn, David McLeod, and Shiv Srivastava
Quantitative features of a common Tmprss2-Erg fusion transcript in prostate cancer
AACR Meeting Abstracts 2007 2007: 371.  

Deepak Kamnasaran, Sameer Agnihotri, Cynthia Hawkins, and Abhijit Guha
The role of GATA4 and GATA6 as putative tumor suppressors and co-modulators in astrocytes
AACR Meeting Abstracts 2007 2007: 372.  

S Edwards, S Bullock, A Amin, Q Hope, S Jugurnauth, N Garcia, S Bryant, S Mulholland, M Guy, L McGuffog, D Easton, Cancer Research UK/BPG/BAUS/UKGPCS Collaborators, The ACTANE Consortium, and R Eeles
Follow up of hints from a genome-wide linkage study in prostate cancer families in the ACTANE Consortium: Results from 270 multiple case families.
AACR Meeting Abstracts 2007 2007: 373.  

Antoine Italiano, Frederique Keslair, Nathalie Cardot, Jean-Michel Coindre, Eric Dumollard, Agnes Leroux, Claire Mainguene, Isabelle Peyrottes, Dominique Ranchere, and Florence Pedeutour
Molecular mapping of the 12q13-15 amplicon and identification of new target oncogenes in well-differentiated liposarcomas rings and giant chromosomes
AACR Meeting Abstracts 2007 2007: 374.  

Daniel Martin-Perez, Esther Sanchez, Lorena Maestre, Miguel Angel Piris, and Margarita Sanchez-Beato
SUZ12 overexpression in human tumors is associated with tumoral transformation and its depletion affects Mantle cell lymphoma cell lines viability.
AACR Meeting Abstracts 2007 2007: 375.  

Louise Williams, Christine Hooi, and Ian Campbell
Functional identification of chromosome 22 candidate tumor suppressor genes in breast cancer.
AACR Meeting Abstracts 2007 2007: 376.  

Yick Fu Wong, T.H. Cheung, K.W.K. Lo, S.F. Yim, N.S.S. Siu, K.W.Y. Wong, and T.K.H. Chung
Global microRNA expression profiles in endometrioid endometrial carcinoma in Hong Kong women
AACR Meeting Abstracts 2007 2007: 377.  

Tatiana Dracheva, Keyong Hong, Sinchita Roy Chowdhuri, Megan Hames, Audrey Player, Izumi Horikawa, Carl Barrett, Jonathan Wiest, Jinghui Zhang, Robert Clifford, Ping Yang, Zhifu Sun, Marie-Christine Aubry, and Jin Jen
- Identification of a candidate gene on chromosome 3p21 potentially involved in early age onset lung cancer
AACR Meeting Abstracts 2007 2007: 378.  

Daniel Nowak, Florian Wagner, Maximilian Mossner, Olaf Hopfer, Verena Serbent, Claudia Baldus, Dieter Hoelzer, Eckhard Thiel, and Wolf Hofmann
Combined analysis of loss of heterozygosity and DNA copy number by high-resolution SNP arrays identifies minimal genomic deletions in CD34+ cells purified from patients with MDS
AACR Meeting Abstracts 2007 2007: 379.  

Xu Song, Ling Li, Xinxin Tong, Guangfeng Zhang, Ziyi Zhao, Chuanfang Wu, and Alan Garen
Human noncoding RNAs inhibit the binding of PSF protein and DNA.
AACR Meeting Abstracts 2007 2007: 380.  

Pharmacokinetics: Poster Presentations - Late-Breaking Abstracts:Back

Carlo Bello, Hai-Zhi Bu, Shem Patyna, Ping Kang, Geoffrey Peng, William Pool, John Smeraglia, Laurie Sherman, May Garrett, and Karen Klamerus
A phase I mass-balance study to evaluate the metabolism and excretion of [14C]-sunitinib (SU11248) in healthy male subjects
AACR Meeting Abstracts 2007 2007: LB-354.  

Kyriakos Papadopoulos, Robert Setlik, John Sarantopoulos, Paula Fracasso, Alvin Wong, Kenneth Duchin, Dorothy Martinez-Bonugli, and Anthony Tolcher
Phase I pharmacokinetic interaction and safety study of DN-101/docetaxel in patients with advanced solid tumors
AACR Meeting Abstracts 2007 2007: LB-355.  

Phase II Clinical Trial Data: Poster Presentations - Late-Breaking Abstracts:Back

Gerold Bepler, Charles Williams, Alberto Chiappori, Eric Haura, Tawee Tanvetyanon, Scott Antonia, and George Simon
Phase II trial using the DNA synthesis and damage repair genes RRM1 and ERCC1 for chemotherapy selection in advanced non-small-cell lung cancer (NSCLC)
AACR Meeting Abstracts 2007 2007: LB-358.  

Luigi Lenaz, Daniel Pertschuk, Shanta Chawla, Bela Denes, Chrisopher Nardo, Dorla Mirejovsky, and L.D. Vainchtein
Effect on wound healing and pharmacokinetics of single intravesical administration of apaziquone (EOquin®) immediately following transurethral resection of superficial bladder cancer
AACR Meeting Abstracts 2007 2007: LB-359.  

Vaccines: Poster Presentations - Late-Breaking Abstracts:Back

Hans Loibner
Low lymphocyte counts at baseline of stage IV cancer patients treated with the cancer vaccine IGN101 predict prolonged survival : A retrospective analysis of a double-blind placebo controlled Phase II study
AACR Meeting Abstracts 2007 2007: LB-362.  

Colon and other gastrointestinal cancers: Poster Presentations - Late-Breaking Abstracts:Back

Frederico Costa, Andre Cosme de Oliveira, Roberto Meirelles Jr, Jr, Rodrigo Surjan, Tatiana Zanesco, Maria Cristina Chammas, Alexandre Barbault, and Boris Pasche
A phase II study of amplitude-modulated electromagnetic fields in the treatment of advanced hepatocellular carcinoma
AACR Meeting Abstracts 2007 2007: LB-363.  

Novel antitumor agents: Oral Presentations - Late-Breaking Abstracts:Back

Dajun Yang, Sanjeev Kumar, Xiongwen Zhang, Dongguang Qin, Sanmao Kang, Ke King, Su Qiu, Meilan Liu, Zaneta Nikolovska-Coleska, Donna McEachern, Rebecca Miller, Yipin Lu, Shanghai Yu, Guoping Wang, Jianyong Chen, Xiaolan Ling, Yanqiong Lin, Shi Liu, Ping Min, Jay Stoudemire, and Shaomeng Wang
Preclinical characterization of MI-219, A novel, potent and orally active small molecule inhibitor of the MDM2-p53 interaction.
AACR Meeting Abstracts 2007 2007: LB-365.  

Drug design: Oral Presentations - Late-Breaking Abstracts:Back

Jarrett Remsberg, Sergey Tarasov, and Nadya Tarasova
Structural analogs of Smoothened intracellular loops as potent inhibitors of cancer cell growth
AACR Meeting Abstracts 2007 2007: LB-366.  

Tyrosine kinase and phosphatase inhibitors: Oral Presentations - Late-Breaking Abstracts:Back

Cai-hong Yun, Michelle Woo, Heidi Greulich, Matthew Meyerson, Kwok Kin Wong, and Michael Eck
EGFR kinase mutations in NSCLC: Unexpected structural and kinetic insights into the mechanism of the T790M resistance mutation and its inhibition by irreversible inhibitors including HKI-272
AACR Meeting Abstracts 2007 2007: LB-367.  

Protein and lipid kinases: Oral Presentations - Late-Breaking Abstracts:Back

Mohammad Azam and George Daley
A Unified Mechanism of Tyrosine Kinase Activation by the Mutation of the Gatekeeper Residue Threonine
AACR Meeting Abstracts 2007 2007: LB-368.  

Metabolism and survival pathways: Oral Presentations - Late-Breaking Abstracts:Back

Jieru Lin, Peng Li, Adam Snook, Stephanie Schulz, Giovanni Pitari, and Scott Waldman
Guanylyl Cyclase C is the metabolic switch for the Warburg effect in colorectal cancer
AACR Meeting Abstracts 2007 2007: LB-369.  

Diet, alcohol, smoking, and other lifestyle risk factors: Oral Presentations - Late-Breaking Abstracts:Back

Andrew Flood, Tanuja Rastogi, Elisabet Wirfalt, Panagiota Mitrou, Jill Reedy, Amy Subar, Viktor Kipnis, Doug Midthune, Traci Mouw, Michael Leitzmann, and Arthur Schatzkin
Dietary patterns and incident colorectal cancer among middle aged Americans: The NIH-AARP Diet and Health Study
AACR Meeting Abstracts 2007 2007: LB-370.  

Traci Mouw, Annemarie Koster, Margaret Wright, Madeleine Blank, Albert Hollenbeck, and Arthur Schatzkin
Education level and risk of cancer incidence in the NIH-AARP Diet and Health Study
AACR Meeting Abstracts 2007 2007: LB-371.  

Therapeutic antibodies: Oral Presentations - Late-Breaking Abstracts:Back

Mark Merchant, Zhong Zheng, Maria Romero, Arthur Huang, Camellia Adams, Barbara Moffat, Min Zhang, Yvonne Chen, Liping Wang, Monique La Fleur, Janet Tien, Sarajane Ross, Minhong Yan, William Mallet, Hani Bou Reslan, Jed Ross, Richard Carano, Renhui Yang, Hongkui Jin, Gail Colbern, Mark Dennis, Daniel Yansura, and Ralph Schwall
One-armed 5D5 (OA5D5) is a potent humanized HGF-blocking anti-c-Met monovalent antibody that inhibits HGF-dependent activity in vitro and demonstrates anti-tumor efficacy in vivo
AACR Meeting Abstracts 2007 2007: LB-372.  

Drug transport and metabolism: Oral Presentations - Late-Breaking Abstracts:Back

Olaf van Tellingen, Serena Marchetti, Nienke de Vries, Jin Zhao, Tessa Buckle, Jos Beijnen, and Jan Schellens
The impact of the ABC transporters P-gp and BCRP on the oral bioavailability and brain penetration of erlotinib using drug transporter knockout mouse models.
AACR Meeting Abstracts 2007 2007: LB-373.  

Cell cycle mechanisms of anticancer drug action: Oral Presentations - Late-Breaking Abstracts:Back

Peter Charlton, James Westcott, Phillip Reaper, Mark Anderton, Peter Weber, Graham Cheetham, and John Pollard
A novel inhibition mechanism of Aurora kinases by the MK-0457 (VX-680) class of compounds confers potent cell activity and an advantageous pharmacodynamic profile
AACR Meeting Abstracts 2007 2007: LB-374.  

Cancer stem cells: Oral Presentations - Late-Breaking Abstracts:Back

Phedias Diamandis, Jan Wildenhain, Ian D. Clarke, Adrian G. Sacher, Jeremy Graham, David S. Bellows, Erick K. Ling, Ryan J. Ward, Leanne G. Jamieson, Mike Tyers, and Peter B. Dirks
Chemical genetic screening reveals novel chemotherapeutic targets for brain tumor stem cells
AACR Meeting Abstracts 2007 2007: LB-376.  

Metastasis genes and models: Oral Presentations - Late-Breaking Abstracts:Back

Anguraj Sadanandam, Michelle Varney, Abdulkader Ashour, and Rakesh Singh
SEMA5A EXPRESSION IN PANCREATIC CANCER IS ASSOCIATED WITH TUMOR PROGRESSION AND METASTASIS
AACR Meeting Abstracts 2007 2007: LB-377.  

Proteomics and biomarker discovery: Oral Presentations - Late-Breaking Abstracts:Back

Eduardo Dias, Lisa Zimmerman, Amy-Joan Ham, Daniel Liebler, Carlos Arteaga, and Melinda Sanders
Shotgun proteomic analysis of 1500 laser captured microdissected cells from breast tumor tissue using a short stack SDS-PAGE/in-gel digestion and LC-MS/MS
AACR Meeting Abstracts 2007 2007: LB-378.  

Developmental phenotypes of cancer genes: Oral Presentations - Late-Breaking Abstracts:Back

Rami Aqeilan, John Hagan, Stefano Volinia, Francesco Trapasso, Valentina Donati, Dean Marshall, Alain de Bruin, Mohammad Hassan, Sadiq Hussain, Suk-Hee Lee, Gary Stein, Jane Lian, and Carlo Croce
Targeted deletion of Wwox leads to postnatal lethality, impaired steroidogenesis and bone growth retardation
AACR Meeting Abstracts 2007 2007: LB-380.  

Molecular Genetics 2: Poster Presentations:Back

Ageliki Georgopoulos, Amr Soliman, Celina Kleer, An-Chi Lo, Saad Eissa, Hussein Khaled, Sherif Omar, and Sofia Merajver
Molecular differences between inflammatory and non-inflammatory breast cancers in egyptian patients
AACR Meeting Abstracts 2007 2007: 381.  

Sam Wiseman, Obi Griffith, Adrienne Melck, Hamid Masoudi, Ashish Rajput, and Steven Jones
Evaluation of type 1 growth factor receptor family expression in 205 thyroid lesions reveals diagnostic utility and targeted therapeutic potential for HER1, HER3, and HER4
AACR Meeting Abstracts 2007 2007: 382.  

Mingzhou Guo, Joshi Alumkal, Tatiana Drachova, Jin Jen, and James Herman
CHFR methylation strongly correlates with methylation of DNA damage repair and apoptotic pathway genes in non small cell lung cancer
AACR Meeting Abstracts 2007 2007: 383.  

Norihiko Kawamata, Seishi Ogawa, Martin Zimmermann, Masashi Sanada, Kari Hemminki, Go Yamatomo, Yasuhito Nannya, Rolf Koehler, Thomas Flohr, Carl Miller, Jochen Harbott, Wolf-Dieter Ludwig, Martin Stanulla, Martin Schrappe, Claus Bartram, and Phillip Koeffler
PAX5 gene is rearranged to a variety of partner genes and generates novel fusion genes in pediatric acute lymphoblastic leukemia.
AACR Meeting Abstracts 2007 2007: 384.  

Tomohiko Hara, Kazufumi Honda, Miki Shitashige, Masaya Ono, Hideyasu Matsuyama, Katsusuke Naito, Setsuo Hirohashi, and Tesshi Yamada
Actinin-4-mediated inhibition of cell proliferation and mass spectrometry analysis of the native protein complex containing actinin-4 in prostate cancer cells.
AACR Meeting Abstracts 2007 2007: 385.  

Shigeki Umemura, Nobukazu Fujimoto, Akio Hiraki, Kenichi Gemba, Nagio Takigawa, Keiichi Fujiwara, Masahiro Tabata, Katsuyuki Kiura, Hiroshi Ueoka, Takumi Kishimoto, and Mitsune Tanimoto
Identification of aberrant promoter hypermethylation in serum DNA is useful for lung cancer detection in patients with pulmonary silicosis
AACR Meeting Abstracts 2007 2007: 386.  

Chueh-Chuan Yen, Wei-Ming Chen, Winby Chen, Tain-Hsiung Chen, Hong-Jen Chiou, Giun-Yi Hung, Hung-Ta Wu, Chao-Jung Wei, Cheng-Ying Shiau, Yu-Chung Wu, Po-Min Chen, Ta-Chung Chao, Chi-Hung Lin, Yann-Jang Chen, and Jonathan Fletcher
Osteosarcoma genomic amplifications and deletions evaluated by single nucleotide polymorphism (SNP) arrays: demonstration of LSAMP tumor suppressor mechanism
AACR Meeting Abstracts 2007 2007: 387.  

Takafumi Nishimura
Genome alterations in sporadic gastrointestinal cancer: a comprehensive review in the literature
AACR Meeting Abstracts 2007 2007: 388.  

Norihiko Kawamata, Seishi Ogawa, Martin Zimmermann, Masashi Sanada, Kari Hemminki, Go Yamatomo, Yasuhito Nannya, Rolf Koehler, Thomas Flohr, Carl Miller, Jochen Harbott, Wolf-Dieter Ludwig, Martin Stanulla, Martin Schrappe, Claus Bartram, and Phillip Koeffler
Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high resolution single nucleotide polymorphism oligonucleotide microarray.
AACR Meeting Abstracts 2007 2007: 389.  

Jasmine Healy, Helene Belanger, Mathieu Lariviere, Damian Labuda, and Daniel Sinnett
Functional promoter SNPs in TGFβ1 and the susceptibility to childhood leukemia
AACR Meeting Abstracts 2007 2007: 390.  

Chun-Ling Gao, Bungo Furusato, David McLeod, Shiv Srivastava, Gyorgy Petrovics, and Isabell Sesterhenn
Mapping of TMPRSS2-ERG fusion in multi-focal prostate cancer
AACR Meeting Abstracts 2007 2007: 391.  

Wai Ip, Jennifer Gho, Kathy Chan, Paul Lai, and Nathalie Wong
Functional characterizations of candidate tumor suppressor gene ATF5 in hepatocellular carcinoma
AACR Meeting Abstracts 2007 2007: 392.  

Guillaume Serin, Violette Thermes, Frederic Vincent, Jochen Wittbrodt, Jean-Stephane Joly, and Philippe Genne
Identification by systematic in situ hybridization screen on medaka embryos of new genes as targets for anti-cancer therapy
AACR Meeting Abstracts 2007 2007: 393.  

Michio Sugita, Eiji Nakajima, Harubumi Kato, Paul Bunn, Wilbur Franklin, and Fred Hirsch
PCR method for detection of EGFR exon 19 deletion in NSCLC
AACR Meeting Abstracts 2007 2007: 394.  

Ajay Pandita, Jana Pederova, Jane Bayani, Paula Marrano, Mona Prasad, Maria Zielenska, and Jeremy Squire
Concurrent sub-microscopic deletion accompanies generation of MYCN amplicon: Mechanistic implications
AACR Meeting Abstracts 2007 2007: 396.  

Liang Wang, Shannon McDonnell, Joshua Slusser, Scott Hebbring, Julie Cunningham, Steven Jacobsen, James Cerhan, Michael Blute, Daniel Schaid, and Stephen Thibodeau
Two common chromosome 8q24 variants are associated with increased risk for prostate cancer
AACR Meeting Abstracts 2007 2007: 397.  

Dirk Kemming, Ulf Vogt, Thomas Dittmar, and Burkhard Brandt
The role of early placenta insulin-like growth factor (EPIL) as a potential regulator of cancer progenitor cells
AACR Meeting Abstracts 2007 2007: 398.  

Paulette mhawech-fauceglia, Wiam bshara, Stacey south, Chris andrews, Shashikant lele, and Kunle odunsi
PSMA mRNA and protein expression as potential prognostic markers in endometrial adenocarcinoma
AACR Meeting Abstracts 2007 2007: 399.  

Tao Tang, Chi Wang, Yick Wong, Keith Lo, Wai Lui, Tony Chung, and Kwong Choy
Characterizing abberrantly expressed microRNAs in chromosome 7 in cervical carcinoma
AACR Meeting Abstracts 2007 2007: 400.  

Luciane Cavalli, Yan Man, Arnold Schwartz, Bassem Haddad, and Patricia Berg
DNA amplification of the BP1 homeobox gene in breast cancer
AACR Meeting Abstracts 2007 2007: 401.  

Jun Wang, Jennifer Jarrett, Yeon Chung, Robert Satcher, and Anait Levenson
Molecular determinants of hormone-dependent breast cancer bone metastases
AACR Meeting Abstracts 2007 2007: 402.  

Daniel Cabral, Heather Feaman, Michael Sheard, and C. Reynolds
Short tandem repeat genotyping using identifilerTM is a reproducible and cost-effective method for establishing and monitoring identity of pediatric cancer cell lines
AACR Meeting Abstracts 2007 2007: 403.  

Hans Neubauer, Susan Clare, Wojciech Wozny, Karl Sotlar, Diethelm Wallwiener, Raffael Kurek, Michael Cahill, Erich Solomayer, and Tanja Fehm
Increased wound-response revealed by proteomics of estrogen receptor-negative breast cancers
AACR Meeting Abstracts 2007 2007: 404.  

Micheala Aldred, E Ruteshouser, Rachael Natrajan, Paul Grundy, Jeffrey Dome, Vicki Huff, and Chris Jones
Loss of heterozygosity analysis in sporadic Wilms' tumor defines at least one novel tumor suppressor locus at 2q37
AACR Meeting Abstracts 2007 2007: 405.  

Tongzhong Ju, Grainger S. Lanneau, Tripti Gautam, Yingchun Wang, Baoyun Xia, Sean Stowell, Margaret Willard, Doris Benbrook, Marie Hanigan, and Richard Cummings
Human tumor antigens arising from mutations in Cosmc
AACR Meeting Abstracts 2007 2007: 406.  

Xinning Wang and Warren Heston
Folate hydrolase assay and binding studies of PC3 cells transfected with mutant prostate specific membrane antigen
AACR Meeting Abstracts 2007 2007: 407.  

Receptor Tyrosine Kinase Inhibitors: Oral Presentations - Invited Abstracts:Back

Tona Gilmer
Lapatinib: A novel approach to inhibit EGFR(ErbB1)/HER2(ErbB2)
AACR Meeting Abstracts 2007 2007: SY04-01.  

The Challenge of Applying Molecular Signatures in the Clinic: The SPECS Perspective: Oral Presentations - Invited Abstracts:Back

Wing Chan
The challenge of evaluating diagnostic signatures for non-Hodgkin’s lymphomas in multiple institutions
AACR Meeting Abstracts 2007 2007: SS04-01.  

Yipeng Wang, James Koziol, Steve Goodison, JianHua Lou, Dan Mercola, and Michael McClelland
The challenge of developing predictive signatures for the outcome of newly diagnosed prostate cancer based on expression analysis and genetic changes of tumor and non-tumor cells
AACR Meeting Abstracts 2007 2007: SS04-02.  

Matthew Ellis, Charles Perou, Torsten Nielsen, Elaine Mardis, Mark Watson, and Philip Bernard
The challenges and pitfalls of delivering breast cancer multigene diagnostic assays to the clinic
AACR Meeting Abstracts 2007 2007: SS04-03.  

Positive and Negative Growth Signaling: Poster Presentations:Back

Melodie Knowlton, Carolyn Wrobel, Ting-Lei Gu, Bryan Ballif, Steven Gygi, Roberto Polakiewicz, and Joan Brugge
PhosphoScan® analysis reveals insights into the mechanisms responsible for disruption of cell-cell adhesion mediated by activation of the CSF-1R in mammary epithelial cells
AACR Meeting Abstracts 2007 2007: 408.  

Adam Durbin, Gino Somers, Michael Forrester, Gregory Hannigan, and David Malkin
A c-Jun NH2 terminal kinase-dependent activation switch determines the oncogenic or tumor suppressive activity of integrin-linked kinase in rhabdomyosarcoma
AACR Meeting Abstracts 2007 2007: 409.  

Akira Matsushita, Tobias Gotze, Jason Gunn, and Murray Korc
Neuropilin-1 associates with c-Met and modulates hepatocyte growth factor actions
AACR Meeting Abstracts 2007 2007: 410.  

Pankaj Taneja, Ali Mallakin, Donna Frazier, Lauren Matise, Mayur Choudhary, Samantha Allen, Mark Willingham, and Kazushi Inoue
Critical role of Dmp1 in HER2/neu signaling and in normal breast epithelial development
AACR Meeting Abstracts 2007 2007: 411.  

Darci Butcher, Julie Friedland, Manunya Nuth, Patrick Humbert, and Valerie Weaver
Force-dependent disruption of scribble/Dgl5-dependent tissue polarity.
AACR Meeting Abstracts 2007 2007: 412.  

Bo Cen, Haiyang Li, and I. Bernard Weinstein
HINT1 inhibits proteasome-mediated degradation of p21CIP1 and p27KIP1
AACR Meeting Abstracts 2007 2007: 413.  

Akiko Uchida, Seiki Hirano, Hiroyuki Kitao, Atsuko Ogino, Kanmei Rai, Shinichi Toyooka, Nagio Takigawa, Masahiro Tabata, Minoru Takata, Katsuyuki Kiura, and Mitsune Tanimoto
Activation of downstream EGFR signaling provides Gefitinib-resistance in cells carrying EGFR mutation
AACR Meeting Abstracts 2007 2007: 414.  

My-Anh Wioland, Dallas Lobreau, Gregory White, Pierre Falardeau, and henriette Gourdeau
ECO-4601 inhibits the Ras MAPK signaling pathway by dislodging Ras from the cell plasma membrane
AACR Meeting Abstracts 2007 2007: 415.  

Rong Wu, Salvatore Coniglio, Amanda Chan, Marc Symons, and Bettie Steinberg
Pak1 and Pak 2 kinases contribute to COX-2 expression in respiratory papillomas
AACR Meeting Abstracts 2007 2007: 416.  

Jian Cui and Albert Wong
Dimerization of JNK2{alpha}2 precedes its autophosphorylation
AACR Meeting Abstracts 2007 2007: 417.  

Alice Larsen, Marie Stockhausen, and Hans Poulsen
The role of EGF-induced EphA2 expression in EGFR mediated cancer cell proliferation and motility
AACR Meeting Abstracts 2007 2007: 418.  

David Shattuck, Jamie Miller, Kermit Carraway, and Colleen Sweeney
LRIG1 negatively regulates Met Receptor and suppresses changes associated with HGF stimulation in breast cancer lines
AACR Meeting Abstracts 2007 2007: 419.  

Guosheng Huang, Min Yan, Stefano Monti, Rosana Eisenberg, Ayad Hamdan, Todd Golub, Daniel Tenen, Sanford Markowitz, and Balazs Halmos
15-hydroxyprostaglandin dehydrogenase (15-PGDH) is a target gene of the candidate tumor suppressor, HNF3β in lung cancers
AACR Meeting Abstracts 2007 2007: 420.  

Tomoya Yokota, Yanna Liu, Kelly Hunt, and Khandan Keyomarsi
C/EBPβ-elafin pathway is involved in generation of cyclin E low molecular weight isoforms in breast cancer
AACR Meeting Abstracts 2007 2007: 421.  

Hongjuan Zhao, Zuxiong Chen, Rosie Nolley, and Donna Peehl
Expression and function of Monoamine oxidase A in normal prostate cells
AACR Meeting Abstracts 2007 2007: 422.  

Abbes Belkhiri and Wael El-Rifai
t-Darpp antagonizes ceramide-induced apoptosis: up-regulation of Bcl2 through active CREB/ATF-1
AACR Meeting Abstracts 2007 2007: 423.  

Douglas Burtrum, Bronek Pytowski, and Dale Ludwig
Abrogation of PTEN does not confer resistance to anti-IGF-IR targeted therapy in IGF responsive tumor cells
AACR Meeting Abstracts 2007 2007: 425.  

Lora Tucker, Qian Zhang, Julie Wilsbacher, Robert Hubbard, George Sheppard, Steven Davidsen, Randy Bell, and Jieyi Wang
Characterization of cancer cells that have lost their oncogene addiction
AACR Meeting Abstracts 2007 2007: 426.  

Makoto Watanabe, Lin Huang, Masabumi Shibuya, Nobuo Tsuchida, and Noriko Gotoh
Unique role of FRS2beta adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways
AACR Meeting Abstracts 2007 2007: 427.  

Xiaoling Zhou, Nicholas Popescu, George Klein, and Stephan Imreh
The transmembrane protein TMEM7 is an IFN-{alpha} responsive gene that suppresses cell proliferation and is down-regulated in human hepatocellular carcinoma.
AACR Meeting Abstracts 2007 2007: 428.  

Daqing Wu, Shareen Iqbal, Seong IL Seo, Haiyen Zhau, Mitch Sokoloff, and Leland Chung
Vascular endothelial growth factor (VEGF) is a survival factor in metastatic human prostate cancer cells via induction of myeloid cell leukemia-1 (Mcl-1)
AACR Meeting Abstracts 2007 2007: 429.  

Anna Moshnikova, Sergey Kuznetsov, and Andrei Khokhlatchev
Interaction of the growth and tumor suppressor NORE1A with microtubules
AACR Meeting Abstracts 2007 2007: 430.  

Ke Yao, Yong-Yeon Cho, Ann Bode, and Zigang Dong
NFAT3, a substrate of JNKs, is a negative regulator of Ras-JNK-induced cell transformation
AACR Meeting Abstracts 2007 2007: 431.  

Thamara Abouantoun
Gene expression induced by the platelet-derived growth factor receptors (PDGFR) alpha and beta in childhood medulloblastomas
AACR Meeting Abstracts 2007 2007: 432.  

Liv Ingrid Flinder, Olga Timofeeva, Carola Rosseland, Lene Wierod, Ellen Skarpen, and Henrik Huitfeldt
Physiological reactive oxygen species (ROS) modulate EGF-induced phosphorylation of ERK2 at the level of EGF receptor
AACR Meeting Abstracts 2007 2007: 433.  

Christine Pratilas, Barry Taylor, Sven Nelander, Olivera Grbovic-Huezo, Agnes Viale, David Solit, Chris Sander, and Neal Rosen
Activating mutation in B-RAF disables normal feedback inhibition of MEK and results in increased output of the RAF/MEK/MAPK signaling pathway.
AACR Meeting Abstracts 2007 2007: 434.  

Jingyan Wei, Weili Yan, Xiuling Li, Wen-Chang Chang, and Hsin-Hsiung Tai
Activation of thromboxane receptors (TPs) induces cyclooxygenase-2 (COX-2) expression through multiple signaling pathways in human lung cancer cells
AACR Meeting Abstracts 2007 2007: 435.  

Keishi Narita, Jeremy Chien, Sally Mullany, Julie Staub, Xiang Qian, Wilma Lingle, and Viji Shridhar
Loss of HSulf-1 expression enhances autocrine signaling mediated by amphiregulin in breast cancer
AACR Meeting Abstracts 2007 2007: 436.  

Steven Smith, Gary Oxford, Henry Frierson, and Dan Theodorescu
Differential expression of Ral GTPases and effectors in urothelial carcinoma
AACR Meeting Abstracts 2007 2007: 437.  

Tumor Suppressors and Tumor Cell Death: Poster Presentations:Back

Ratna Ray, Asish Ghosh, Robert Steele, and Tatsuo Kanda
Inhibition of MBP-1 induces senescence in human foreskin fibroblasts
AACR Meeting Abstracts 2007 2007: 438.  

Alexandre Prieur and Daniel Peeper
Opposite functions of DRIL1, a member of the ARID family DNA-binding proteins, in human and mouse fibroblast senescence
AACR Meeting Abstracts 2007 2007: 439.  

Martha Stampfer, Ekaterina Bassett, Richard Neve, Heidi Feiler, and James Garbe
Long-term culture of normal pre-stasis human mammary epithelial cells and implications for models of human cellular senescence
AACR Meeting Abstracts 2007 2007: 440.  

Nam Deuk Kim, Su-Bog Yee, Mi-Na Kim, Sang Eun Park, Mohammad Akbar Hossain, Min Young Kim, Gi Young Kim, and Yung Hyun Choi
Luteolin induced growth inhibition and apoptosis in hepatoma cells involving TGF-β and Fas/Fas-ligand signaling pathways
AACR Meeting Abstracts 2007 2007: 441.  

Keiko Hiyama, Keiji Tanimoto, Eiso Hiyama, and Masahiko Nishiyama
Exploring genes that regulate cellular proliferation and immortalization of human somatic cells
AACR Meeting Abstracts 2007 2007: 442.  

Maria Fiammetta Romano, Simona Romano, Maria Mallardo, Federico Chiurazzi, Rita Bisogni, and Salvatore Venuta
FK506 binding protein 12-ligands restore TGF-beta response in B cell chronic lymphocytic leukemia
AACR Meeting Abstracts 2007 2007: 443.  

Gunjan Gakhar, Takahiro Ohira, Sreenivas Battina, Duy H. Hua, and Thu Annelise Nguyen
Anti-tumor effect of primaquine compounds in human breast cancer cells
AACR Meeting Abstracts 2007 2007: 444.  

Ekaterina Bassett, James Garbe, Tarlochan Nijjar, Alain Beliveau, Martha Stampfer, and Paul Yaswen
Functional interactions of p57KIP2 and p53 during immortalization of human mammary epithelial cells
AACR Meeting Abstracts 2007 2007: 445.  

Melanie Eichenmuller, Irmela Jeremias, Dietrich von Schweinitz, and Roland Kappler
Betulinic acid induces apoptosis in rhabdomyosarcoma cell lines
AACR Meeting Abstracts 2007 2007: 446.  

Dong-Hui Shin, Hyun-Jun Kim, Ki-Seok Jang, Hak Sung Kim, Heekyoung Chung, and Gu Kong
The in vitro and in vivo anti-tumor effect of decursin in estrogen receptor-negative human breast cancer cells occurs via downregulation of Akt signaling pathway
AACR Meeting Abstracts 2007 2007: 447.  

Ronnie Poon, Ka Tam, Zhen Yang, and Sheung Fan
Both p53 dependent and independent pathways contribute to RAD001 mediated enhancement of chemo-sensitivity in hepatocellular carcinoma
AACR Meeting Abstracts 2007 2007: 448.  

Yingyu Ma, Wei-Dong Yu, Geraldine Flynn, Pamela Hershberger, Rui-Xian Kong, Donald Trump, and Candace Johnson
1,25D3 potentiates the cytotoxic effects of cisplatin through up-regulation of p73 and enhancement of apoptosis in squamous cell carcinoma cells
AACR Meeting Abstracts 2007 2007: 449.  

Chukwuemeka Ihemelandu, Wayne Frederick, Lasalle Leffall, Robert Dewitty, and Tammey Naab
p53, Bcl-2 expression in molecular breast cancer subtypes of Pre-menopausal African-American women.
AACR Meeting Abstracts 2007 2007: 450.  

Flavia Pichiorri, Francesco Trapasso, Marco Gaspari, Tiziana Palumbo, Eugenio Gaudio, Hiroshi Okumura, Di Leva Giampiero, Muller Fabbri, Rodolfo Iuliano, Salvatore Venuta, Luigi Giusto Spagnoli, Kay Huebner, and Carlo Maria Croce
Characterization of a Fhit protein complex suggests a novel pathway to apoptosis of cancer cells
AACR Meeting Abstracts 2007 2007: 451.  

Loretta Lau, Jennifer Nugent, and Meredith Irwin
Differential modulation of p73 isoforms by COX inhibitor in neuroblastoma
AACR Meeting Abstracts 2007 2007: 452.  

Yihong Ma and Doug Cress
Regulation of p57 (Kip2) by the cyclin dependent kinase inhibitor BMS-387032/SNS-032 is dependent on E2F1
AACR Meeting Abstracts 2007 2007: 453.  

Anna Vilgelm, Wael El-Rifai, Jinxiong Wei, and Alexander Zaika
Overexpression of DeltaNp73alpha induces drug resistance in human gastric carcinoma cells through upregulation of the MDR1 gene
AACR Meeting Abstracts 2007 2007: 454.  

Deepak Raj and Douglas Grossman
Regulation of survivin expression by p53 and Rb in normal human melanocytes.
AACR Meeting Abstracts 2007 2007: 455.  

Keli Song, Zainab Jagani, Nordine Benhaga, Jeffery Kutok, and Roya Khosravi-Far
Oncogene-induced regulation of proteasomal degradation pathway: mechanism for tumorigenecity
AACR Meeting Abstracts 2007 2007: 456.  

Crystal Johnson-Holiday, Erica Johnson, Shailesh Singh, and James Lillard
CCR9-CCL25 interaction mediates breast cancer cell survival via Akt activation
AACR Meeting Abstracts 2007 2007: 457.  

Rajesh Singh, James Lillard, William Grizzle, and Shailesh Singh
CCR9-CCL25 interaction involved in prostate cancer cell survival.
AACR Meeting Abstracts 2007 2007: 458.  

Maryam Alrashid and Bernard Bouscarel
FXR plays a key role in the anti-proliferative and apoptotic responses of bile acids in colon carcinoma cell lines.
AACR Meeting Abstracts 2007 2007: 459.  

Sun Baocun, Shiwu Zhang, and Xishan Hao
Elementary study of the relationship between linearly patterned programmed cell necrosis and the succession of blood supply vessel types in melanoma
AACR Meeting Abstracts 2007 2007: 460.  

Metastasis Suppressor and Promoter Genes: Poster Presentations:Back

KIRANMAI GUMIREDDY, F Sun, AJ Klein-Szanto, JM Gibbins, A Saunders, PG Schultz, and Qihong Huang
A novel in vivo selection for metastasis promoting genes in the mouse
AACR Meeting Abstracts 2007 2007: 461.  

Mohammad Malik and Sham Kakar
Securin secures tumor angiogenesis and metastasis
AACR Meeting Abstracts 2007 2007: 462.  

Takanori Kawaguchi
Demonstration and certification of aberrant MUC1 bearing Tn antigen of rat ascites hepatoma AH109A cells with strong lymph node metastasis property
AACR Meeting Abstracts 2007 2007: 463.  

Jinlu Dai, Chris Hall, June Escara-Wilke, and Evan Keller
Wnt5a promotes osteoblastic prostate cancer bone metastases through increasing osteoblastogenesis and invasion
AACR Meeting Abstracts 2007 2007: 464.  

Alix Bee, Youqianq Ke, Ke Lin, Carol Beesley, Sharon Forrest, and Christopher Foster
Ribsomal protein L19 is a promoter of the malignant phenotype of prostate cancer
AACR Meeting Abstracts 2007 2007: 465.  

Rebecca Foster, David Smart, Lucy Elliott, Jessica Meyer, Sally Hampton, Doreen Ashworth, Robert Haigh, Chris Yea, and Marc Princivalle
In vitro evidence for the role of hepsin in metastatic prostate cancer
AACR Meeting Abstracts 2007 2007: 466.  

Donna Hansel, Nicole Prescot, and Raymond Tubbs
HER2 protein expression in metastatic and nonmetastatic urothelial carcinoma
AACR Meeting Abstracts 2007 2007: 467.  

Menghong Sun, Erminia Massarelli, Lei Feng, Natalie Ozburn, Ludmila Prudkin, Guosheng Yin, Ritsuko Komaki, Waun Hong, Kenneth Aldape, and Ignacio Wistuba
Differential immunohistochemical expression pattern of HER family receptors and ligands is detected in primary lung cancers and corresponding brain metastases
AACR Meeting Abstracts 2007 2007: 468.  

Yinglin Lu, Huiyun Lin, Jinqiang Zhang, Xiaogang Tan, Yan Wang, and Yuanji Xu
Is metastasis associated gene Mag-1(LPAAT theta) through activation of mTOR Pathway?
AACR Meeting Abstracts 2007 2007: 469.  

Noel McCabe and Tatiana Byzova
Investigating the role of SPARC in bone metastatic prostate cancer
AACR Meeting Abstracts 2007 2007: 470.  

Nhan Tran, Jeffrey Winkles, Amanda Willis, Julie Chatigny, Hong Vu, Sharron Brown, Nichole Stains, Wendy McDonough, Shannon Fortin, Catherine Mancini, Michael Berens, and Heather Cunliffe
Fn14 promotes invasive behavior of breast cancer cells and correlates with clinical indicators of disease progression
AACR Meeting Abstracts 2007 2007: 471.  

Simon Davies, Colin Dent, Garath Watkins, Judy King, Kefah Mokbel, and Wen Jiang
Expression of the cell to cell adhesion molecule, ALCAM, in breast cancer patients and the potential link with skeletal metastasis
AACR Meeting Abstracts 2007 2007: 472.  

Alejandro Urtreger, Santiago Werbajh, Frank Verrecchia, Alain Mauviel, Lydia Puricelli, Alberto Kornblihtt, and Elisa Bal de Kier Joffe
Fibronectin is the main downregulated gene in MM3 mammary tumor cells and correlates with their increased metastatic potential
AACR Meeting Abstracts 2007 2007: 473.  

George Naumov, Hongbin Ji, Takeshi Shimamura, and Kwok-Kin Wong
LKB1 kinase activation as a suppressor of lung metastases in an animal model of non-small cell lung cancer
AACR Meeting Abstracts 2007 2007: 474.  

Kenji Ikuta, Shinsaku Ohtsuka, Seiji Yano, Soji Kakiuchi, Hirokazu Ogino, Hisanori Uehara, Takashi Takahashi, and Saburo Sone
Role and regulatory mechanism of Endothelin-1 in osteoblastic bone metastasis produced by a human lung adenocarcinoma cell line
AACR Meeting Abstracts 2007 2007: 475.  

D Badgwell, Z Lu, RZ Luo, Y Yu, J Bao, WL-S Liao, and RC Bast
Re-expression of the tumor suppressor gene ARHI decreases ovarian cancer cell motility by inhibiting Stat3 signaling
AACR Meeting Abstracts 2007 2007: 476.  

Peixin Dong, Mitsuhiro Tada, Jun-ichi Hamada, Akihiro Nakamura, Tetsuya Moriuchi, and Noriaki Sakuragi
p53 dominant-negative mutant R273H promotes invasion and migration of human endometrial cancer HHUA cells
AACR Meeting Abstracts 2007 2007: 477.  

Xiaoling Zhou, Drazen Zimonjic, Marian Durkin, Sang-Won Park, and Nicholas Popescu
DLC-1 suppresses distant dissemination of human hepatocellular carcinoma cells in nude mice.
AACR Meeting Abstracts 2007 2007: 478.  

Milinda Esquivel, Roslyn Alonzo, Elissa Donzis, Kounosuke Watabe, Therese Commes, and Linda deGraffenried
The novel metastasis suppressor Drg-1 reverses the invasive potential conferred by Akt in breast and prostate cancer cells
AACR Meeting Abstracts 2007 2007: 479.  

Choon Yee Tan and Christina Ling Chang
Metastasis-associated alterations of NDP kinase A/NM23-H1 affect neuron-like differentiation via Rho GTPase pathways in human neuroblastoma cells
AACR Meeting Abstracts 2007 2007: 481.  

Megumi Iiizumi, Sonia Mohinta, Wen Liu, Sucharita Bandyopadhyay, Ying Wang, Rui Zhan, Shigeru Hirota, Sadahiro Hosobe, Taisei Tsukada, Kunio Miura, Ken Saito, Therese Commes, David Piquemal, Osamu Yoshie, Eiji Furuta, Sudha Pai, Misako Watabe, and Kounosuke Watabe
Tumor metastasis suppressor Drg-1 up-regulates the expression of the KAI1 gene
AACR Meeting Abstracts 2007 2007: 482.  

Kedar Vaidya, Sitaram Harihar, Pushkar Phadke, David Hicks, Graham Casey, Darryl DeWald, and Danny Welch
Differential signaling imposed by BRMS1 as a potential mechanism for differential growth of breast cancer cells
AACR Meeting Abstracts 2007 2007: 483.  

Douglas Hurst, Blake Moore, Mick Edmonds, Alka Mehta, Kevin Nash, and Danny Welch
Characterization of endogenous BRMS1, and splice variants, in the MCF10 breast cancer progression model
AACR Meeting Abstracts 2007 2007: 484.  

Alexandra Silveira, Yi Xie, Kedar Vaidya, and Danny Welch
BRMS1 binding proteins mSDS3 and RBBP1 serve distinct roles in BRMS1 function
AACR Meeting Abstracts 2007 2007: 485.  

J McCorkle, Mengmeng Yang, and David Kaetzel
Site-directed mutagenesis analysis identifies residues necessary for the multiple enzymatic activities of the metastasis suppressor, nm23-H1
AACR Meeting Abstracts 2007 2007: 486.  

Jon Briggs, Gunhild Maelandsmo, Oystein Fodstad, and Adam Riker
Cystatin M is a putative tumor suppressor gene in melanoma
AACR Meeting Abstracts 2007 2007: 487.  

Jinyi Shao and Hongmiao Sheng
Enhancement of the PI3K pathway by heterozygous disruption of the PTEN promotes intestinal neoplasia in APCmin mouse: roles of osteopontin
AACR Meeting Abstracts 2007 2007: 488.  

Mouse Models of Cancer 1: Imaging Technologies: Poster Presentations:Back

Steven Shnyder, Patricia Cooper, Shofiq Al-Islam, Elsa Pilarinou, Jurjees Hassan, Gordon Jayson, Laurence Patterson, and Michael Bibby
Use of a modified hollow fibre assay to evaluate vascular-targeting agents.
AACR Meeting Abstracts 2007 2007: 489.  

Qian Xie, Yue Guo, Quynh-Ai Lockard, Ryan Thompson, Lisa DeCamp, Troy Giambernardi, Sandra Cottingham, George Vande Woude, Helayne Sherman, and Rick Hay
High resolution micro-ultrasound in vivo imaging of glioblastoma in mice
AACR Meeting Abstracts 2007 2007: 491.  

Fusa Ogata, Ryuichi Azuma, Makoto Kikuchi, Isao Koshima, Kouji Matsumura, and Yuji Morimoto
Novel lymphography using indocyanine green dye for near-infrared fluorescence labeling
AACR Meeting Abstracts 2007 2007: 492.  

Peter Black, Anil Shetty, Gordon Brown, Emilio Esparza-Coss, Adam Metwalli, Piyush Agarwal, David McConkey, John Hazle, and Colin Dinney
Validating bladder cancer xenograft bioluminescence with magnetic resonance imaging requires correction for hypoperfusion, hypoxia and necrosis.
AACR Meeting Abstracts 2007 2007: 493.  

Jeffrey Peterson and Sylvie Kossodo
In vivo tomographic and endoscopic imaging of experimental orthotopic colorectal cancer
AACR Meeting Abstracts 2007 2007: 494.  

Gloria Li, Fuqiu He, Yun-hong Huang, Xuelong Deng, Bixiu Wen, Yueping Liu, Akiko Minami, Ligang Xing, Pat Zanzonico, Qing Chen, and Clifton Ling
A preclinical human tumor model for noninvasive imaging of hypoxia-induced gene expression; comparison of endogenous and exogenous markers of tumor hypoxia
AACR Meeting Abstracts 2007 2007: 495.  

Patrick Logan, Jean-Claude Marshall, Bruno Fernandes, Sebastian Di Cesare, Shawn Maloney, and Miguel Burnier
In vivo imaging of fluorescently labeled human uveal melanoma cells in nude mice
AACR Meeting Abstracts 2007 2007: 496.  

Friederike Teichert, Richard Verschoyle, Peter Greaves, Timothy Gant, Richard Edwards, Donald Jones, Orla Teahan, Ian Wilson, Peter Farmer, William Steward, Andreas Gescher, and Hector Keun
1H NMR metabolic profiling of TRAMP mouse prostate tumor tissue
AACR Meeting Abstracts 2007 2007: 497.  

Rintaro Hashizume, Tomoko Ozawa, Lily Hu, Eduard Dinca, Michael Prados, Charles James, and Nalin Gupta
Application of bioluminescence imaging to the characterization of an orthotopic brainstem tumor in rodents
AACR Meeting Abstracts 2007 2007: 498.  

Peterson Jeffrey and Sylvie Kossodo
Non-invasive optical imaging of lung metastasis and response to cancer therapy
AACR Meeting Abstracts 2007 2007: 499.  

Mukund Seshadri, Arup Bhattacharya, Karoly Toth, and Youcef Rustum
Contrast-enhanced MRI of the vascular response of human tumor xenografts to the chemopreventive agent selenium in vivo: Implications for combination therapy
AACR Meeting Abstracts 2007 2007: 500.  

Meng Yang, Yi Ren, and Robert Hoffman
An imageable bone and multi-organ metastatic model of human neuroblastoma
AACR Meeting Abstracts 2007 2007: 501.  

Tengfei Liu, Yanqin Ding, Weibing Xie, Zuguo Li, Xiaoyan Bai, Xin Li, Weiyi Fang, Caiping Ren, Shuang Wang, Robert Hoffman, and Kaitai Yao
Whole-body GFP imaging of tumor growth, progression, and metastasis in an orthotopic metastatic nasopharyngeal carcinoma model
AACR Meeting Abstracts 2007 2007: 502.  

Kazuhiko Tsuji, Jose Reynoso, Michael Bouvet, Robert Hoffman, Marijana Kopun, and Christof Granzow
Tumor cell dormancy imaged in live mice by dual-color fluorescence
AACR Meeting Abstracts 2007 2007: 503.  

Christopher Hamm, Jeff Stevens, Elio Vanin, Elisabeth Seftor, Maria Bonaldo, and Marcelo Soares
Development and characterization of a bioluminescent Swarm rat chondrosarcoma cell line to study tumor growth and progression in vivo.
AACR Meeting Abstracts 2007 2007: 504.  

Senthil Kumar, Thomas Quinn, and Susan Deutscher
In vivo radioimaging of ErbB-2 expressing tumors using phage derived KCCYSL peptide
AACR Meeting Abstracts 2007 2007: 505.  

Stanley J. Korsmeyer Memorial Symposium: Apoptotic and Non-Apoptotic Cell Death in Cancer: Oral Presentations - Invited Abstracts:Back

Suzanne Cory, Mark van Delft, Simon Willis, Andrew Wei, Lin Chen, Kylie Mason, Clare Scott, Cassandra Vandenberg, Philippe Bouillet, Andreas Strasser, Andreas Strasser, Peter Colman, Andrew Roberts, Jerry Adams, and David Huang
The Bcl-2 Family: Cancer's achilles' heel?
AACR Meeting Abstracts 2007 2007: SY05-01.  

Apoptotic and Non-Apoptotic Cell Death in Cancer: Oral Presentations - Invited Abstracts:Back

Eileen White
Role of autophagy in cancer
AACR Meeting Abstracts 2007 2007: SY05-02.  

Carcinogens in the Environment: Lessons Learned and Forgotten: Oral Presentations - Invited Abstracts:Back

Richard Loeppky
Mechanistic studies on the formation and metabolism of nitrosamines
AACR Meeting Abstracts 2007 2007: SS05-03.  

Pediatric Cancer Biology and Clinical Investigation: Poster Presentations:Back

Lindsay Kilburn, Dorene Rudman, M. John Hicks, Kathy Scorsone, Qin Shu, Xiao-Nan Li, Jingrong Yan, Rodney David, Susan Blaney, Heidi Russell, and M Fatih Okcu
Glutathione S-transferase pi protein expression correlates with progression free survival in patients with neuroblastoma
AACR Meeting Abstracts 2007 2007: 506.  

Bing Kung, Sakeenah Hicks, Huaqing Zhao, Xao Tang, and Naohiko Ikegaki
Biological significance of EPHA2 expression in neuroblastoma
AACR Meeting Abstracts 2007 2007: 507.  

Velasco Cimica, Melissa Smith, Srinivasa Chinni, Suman Jana, Sridhar Mani, and Ganjam Kalpana
Inhibition of primary rhabdoid tumors arising in Ini1+/- knock-out mice by a Cyclin/cdk inhibitor
AACR Meeting Abstracts 2007 2007: 508.  

Jason Canner, Ke Ding, Shaomeng Weng, Dajun Yang, and Jiayuh Lin
A novel small molecular inhibitor targets the MDM2-p53 interaction significantly reducing cell viability in both embryonal and alveolar rhabdomyosarcoma cells with wild-type p53.
AACR Meeting Abstracts 2007 2007: 509.  

Yun Hee Kang, Barbara Szymanska, Nancy Yen, Ulla Wilczynska-Kalak, C. Reynolds, Richard Lock, and Min Kang
Activity of vincristine, L-asparaginase, and dexamethasone against acute lymphoblastic leukemia was enhanced by the Bcl-2 inhibitor ABT-737 in vitro and in vivo
AACR Meeting Abstracts 2007 2007: 510.  

Yue-Xin Ren, Friedrich Graf Finckenstein, Diana Abdueva, Kenneth Weinberg, Timothy Triche, Hiroyuki Shimada, and Michael Anderson
Expression of PAX-FKHR in primary mesenchymal stem cells gives rise to alveolar rhabdomyosarcoma
AACR Meeting Abstracts 2007 2007: 511.  

Murray Norris, Janice Smith, Alan Kwek, Claudia Flemming, Susan Cohn, Wendy London, Allen Buxton, Glenn Marshall, and Michelle Haber
Combined expression of the multidrug transporter genes ABCC1/MRP1, ABCC3/MRP3 and ABCC4/MRP4: a powerful predictor of clinical outcome in childhood neuroblastoma
AACR Meeting Abstracts 2007 2007: 512.  

Junko Takita
Molecular allelokaryotyping analysis of neuroblastoma using high-density SNP-genotyping microarrays
AACR Meeting Abstracts 2007 2007: 513.  

Tao Liu, Andrew Tee, Porro Antonio, Tanya Dwarte, Pei Liu, Murray Norris, Michelle Haber, Giovanni Perini, and Glenn Marshall
MycN blocks neuritic differentiation of neuroblastoma cells by direct transcriptional repression of tissue transglutaminase-2
AACR Meeting Abstracts 2007 2007: 514.  

Kartik Krishnan, Duane Currier, Chand Khanna, and Lee Helman
Using the Ewing's sarcoma fusion gene, EWS-Fli1, to model the earliest steps in oncogenic transformation
AACR Meeting Abstracts 2007 2007: 515.  

Wayne Thomas, Eric Sekyere, Joanna Keating, Anna Raif, Bellamy Cheung, Murray Norris, Michelle Haber, Patricia Armatai, David Kaplan, Freda Miller, William Weiss, and Glenn Marshall
Embryonal cancer initiation: MYCN-mediated mechanisms of resistance to cell death causing embryonal cell persistence
AACR Meeting Abstracts 2007 2007: 516.  

Holger Lode, Yan Zeng, Nicole Huebener, Stefan Fest, Ulrike Schroeder, Silke Weixler, Alexander Schramm, Angelika Eggert, and Gerhard Gaedicke
Fractalkine (CX3CL1) rich neuroblastoma microenvironments favor T-cell mediated eradication of metastases following targeted IL-2 immuncytokine therapy
AACR Meeting Abstracts 2007 2007: 517.  

Young Song, Li-Rong Yu, Jun Wei, Qing-Rong Chen, Steffen Durrinck, Thomas Conrads, Timothy Veenstra, and Javed Khan
Parallel isotope-coded affinity tag (ICAT) analysis and mRNA expression profiling of neuroblastoma; a pilot study
AACR Meeting Abstracts 2007 2007: 518.  

Lu Wang, Violetta Barbashina, Adam Olshen, and Marc Ladanyi
Characterization of CAMTA1, a putative 1p36 cancer gene: effects on cell cycle and gene expression
AACR Meeting Abstracts 2007 2007: 519.  

Danielle White, Sarah Buckley, Claire Humphries, and Susan Burchill
p75NTR expression is up-regulated by death-inducing agents and effects a death response following exposure to NGF in the Ewing’s sarcoma family of tumors (ESFT)
AACR Meeting Abstracts 2007 2007: 520.  

Olga Pena, Rex Moats, Goar Smbatyan, Michael Rosol, and Yves DeClerck
The SDF-1 receptor CXCR4 enhances metastasis in neuroblastoma
AACR Meeting Abstracts 2007 2007: 521.  

Guang Li and Maria Tsokos
Targeting of EWS/FLi-1 by siRNA inhibits survivin expression and sensitizes ESFT cells to TRAIL
AACR Meeting Abstracts 2007 2007: 522.  

Tsen-Yin Lin, Jerry Barnhart, Nino Keshelava, and C. Reynolds
Quantifying overexpression of p53 and MDM2 by flow cytometry identified multi-drug resistant neuroblastoma cell lines, including those retaining p53 function
AACR Meeting Abstracts 2007 2007: 523.  

Zhijie li and Carol thiele
Glycogen synthase kinase-3ß mediates BDNF/TrkB protection of neuroblastoma cells from chemotherapy
AACR Meeting Abstracts 2007 2007: 524.  

Michael Hadjidaniel and C. Reynolds
Antagonism of etoposide cytotoxicity for neuroblastoma by retinoic acid is mediated by the anti-apoptotic bcl-2 family proteins.
AACR Meeting Abstracts 2007 2007: 525.  

Arnauld Verschuur, Claudia Lanvers, Monique den Boer, Andre van Kuilenburg, Massimo Serra, Kathy Pritchard-Jones, Jane Renshaw, Torsten Pietsch, Wolfgang Hartmann, Joachim Boos, Paul Workman, Gilles Vassal, and Huib Caron
Targeting HSP90 in pediatric malignancies by the European Consortium "Innovative Therapies for Children with Cancer"
AACR Meeting Abstracts 2007 2007: 526.  

Peter Houghton, John Maris, Henry Friedman, Stephen Keir, Richard Lock, Hernan Carol, Mayamin Tajbakhsh, Richard Gorlick, E. Kolb, Nino Keshelava, C. Reynolds, Christopher Morton, and Malcolm Smith
Pediatric Preclinical Testing Program (PPTP) evaluation of the multi-targeted kinase inhibitor Sunitinib
AACR Meeting Abstracts 2007 2007: 527.  

Daniela Opel, Christopher Poremba, Thorsten Simon, Klaus-Michael Debatin, and Simone Fulda
Activation of Akt predicts poor outcome in neuroblastoma
AACR Meeting Abstracts 2007 2007: 528.  

Helena Gleissman, Magnus Lindskog, Frida Ponthan, Lotta Elfman, Kogner Per, and John Inge Johnsen
Omega-3 docosahexaenoic acid is toxic to neuroblastoma in vitro and in vivo
AACR Meeting Abstracts 2007 2007: 529.  

Luca Lo Nigro, Benedetta Accordi, Virginia Espina, Giuseppe Basso, Gianni Cazzaniga, Andrea Biondi, Enrico Conte, Emanuel Petricoin, and Lance Liotta
A specific proteomic profile is differentially expressed in childhood leukemias with MLL translocations
AACR Meeting Abstracts 2007 2007: 530.  

K. Jin Yoon, Joanna Remack, Rebecca Bush, Catherine Billups, Joseph Khoury, and Mary Danks
Association of membrane-bound intercellular adhesion molecule-2 (ICAM-2) with alpha-actinin and the actin cytoskeleton as a determinant of the metastatic potential of neuroblastoma cells
AACR Meeting Abstracts 2007 2007: 531.  

Anindya Dasgupta, Lubing Gu, Carlos Alvarado, Muxiang Zhou, and Harry Findley
Prognostic and functional significance of livin expression in neuroblastoma
AACR Meeting Abstracts 2007 2007: 532.  

Xiaolin Wan, Arnulfo Mendoza, Sonal Kalburgi, Brain Harkavy, Choh Yeung, Chand Khanna, and Lee Helman
Interaction of β4 integrin with ezrin: required for metastatic phenotype and activation of mTOR signaling in osteosarcoma
AACR Meeting Abstracts 2007 2007: 533.  

Tumor Microenvironment 1: Poster Presentations:Back

Tao Zuo, Chieh-Ti Kuo, Sandya Liyanarachchi, Pearlly Yan, Tim Huang, and Huey-Jen Lin
Dysregulated Jak-Stat and Wnt signaling pathways in breast tumor microenviroment.
AACR Meeting Abstracts 2007 2007: 534.  

Takaomi Okawa, Carmen Michaylira, Charles Miller, Douglas Stairs, and Anil Rustgi
Physical microenvironment influences invasion of genetically engineered esophageal cancer cells into the underlying extracellular matrix in organotypic culture.
AACR Meeting Abstracts 2007 2007: 535.  

In Woo, Sook Hong, Jae Byun, Byung Shim, and Hae Jeon
Stromal Cell Derived Factor 1-alpha (SDF1-{alpha}) is associated with distant metastasis in gastric carcinoma patients
AACR Meeting Abstracts 2007 2007: 536.  

Jason Chia-Hsien Cheng, Chia Hung Chou, and Che-Ming Teng
MMP-9 involves radiation-enhanced in vitro invasiveness and in vivo pulmonary metastasis of Lewis lung carcinoma
AACR Meeting Abstracts 2007 2007: 537.  

Varinder Jeet, Kim Ow, Eboney Doherty, Ben Curley, Pamela Russell, and Aparajita Khatri
Broadening of transgenic adenocarcinoma of the mouse prostate (TRAMP) model to represent late stage hormone refractory cancer
AACR Meeting Abstracts 2007 2007: 538.  

Roya Navab, James Yun, Ming Li, and Ming-Sound Tsao
Carcinoma-associated fibroblasts can enhance tumorigenicity in human lung cancer
AACR Meeting Abstracts 2007 2007: 539.  

Debabrata Banerjee, Sonia Picinich, and John Glod
Investigating the role of tumor-secreted factors in chemotaxis of mesenchymal stem cells to the tumor microenvironment.
AACR Meeting Abstracts 2007 2007: 540.  

Julia Dixon, Simon Williams, Ivan Litvinov, John Isaacs, and Samuel Denmeade
Generation of recombinant prostate specific antigen with a novel strategy
AACR Meeting Abstracts 2007 2007: 541.  

Zachary Kohutek, Sean Aeder, and Isa Hussaini
Protein Kinase C-{alpha}, {delta}, and {eta} differentially regulate MMP-9 activity and invasion in glioblastoma cells
AACR Meeting Abstracts 2007 2007: 542.  

Arash Rafii, Elodie Ducros, Pejman Mirshahi, Anne-Marie Faussat, Jean-Pierre Marie, Gilles Favre, Jeanine Soria, and Massoud Mirshahi
Acquisition of an SDF-1-induced invasive phenotype by breast adenocarcinomas cells MDA-MB231; Role of bone marrow stromal cells and involvement of Rho GTPases.
AACR Meeting Abstracts 2007 2007: 543.  

Walter Carney, Sheryl Brown-Shimer, Karen Pierce, Peter Hamer, Jessica Ramirez, Victor Gaur, Kim Leitzel, Phillip Kantoff, William Oh, Dean Evans, Suhail Ali, and Allan Lipton
Elevated levels of circulating TIMP-1 associated with cancer progression and poor clinical outcomes
AACR Meeting Abstracts 2007 2007: 544.  

Rave Sanker Ezhilarasan, Unmesh Jadhav, Indra Mohanam, Jasti Rao, and Sanjeeva Mohanam
The hemopexin domain of MMP-9 inhibits invasion of human glioblastoma cells and capillary formation by endothelial cells in vitro
AACR Meeting Abstracts 2007 2007: 545.  

Fatima Khwaja, Abdessamad Zerrouqi, Devi Saroja, and Erwin Van Meir
A novel tumor suppressive mechanism For p53: induction of apoptosis in bystander cells through galectin-3 (Gal-3) secretion
AACR Meeting Abstracts 2007 2007: 546.  

Zhuo Tang, Minghuan Yu, and Mary Kosir
Invasion by comedo type ductal carcinoma in situ (DCIS) and the expression of CXCL7 and VEGF-D
AACR Meeting Abstracts 2007 2007: 547.  

Mi Suk Kim, Jong Bae Park, Heon Yoo, Sang Hoon Shin, and Seung Hoon Lee
Hyaluronan induces MMP-9 secretion through FAK-IKK/I{kappa}B{alpha} pathways and 17-AAG down-regulates these pathways in human glioma cells
AACR Meeting Abstracts 2007 2007: 548.  

Heidi McKean, Matthew Goetz, Daniel Visscher, Fergus Couch, Vera Suman, James Ingle, Mark Erlander, Xiao-Jun Ma, and Denis Sgroi
HOXB13 to IL17BR gene expression ratio is not associated with tumor infiltrating lymphocytes in estrogen positive, node negative breast cancer
AACR Meeting Abstracts 2007 2007: 549.  

Su Jin Cho, Nam Hee Won, Han Kyeom Kim, and Aeree Kim
Akt- and MAPK-mediated activation and secretion of MMP-9 into stroma upon heregulin treatment in breast cancer cell
AACR Meeting Abstracts 2007 2007: 550.  

Juan Chen and Jie Li
Inhibiting the aggressive behavior of melanoma cells by blocking the expression of extracellular matrix laminin-10
AACR Meeting Abstracts 2007 2007: 551.  

Joydeep Mukherjee, Amparo Wolf, and Abhijit Guha
Differential role of Neuropilin1 in regulating angiogenesis vs. invasion in the center vs. periphery of human glioblastoma multiforme (GBM)
AACR Meeting Abstracts 2007 2007: 552.  

Rave Sanker Ezhilarasan, Indra Mohanam, Meenakshi Shanmugasundaram, Kathiravan Govindarajan, Jasti Rao, and Sanjeeva Mohanam
Increased survival and angiogenic capabilities of hypoxic endothelial cells following exposure to irradiated tumor conditioned medium
AACR Meeting Abstracts 2007 2007: 553.  

Kadir Demircan, Esra Gunduz, Mehmet Gunduz, Satoshi Hirohata, Levent Beder, Hitoshi Nagatsuka, Beyhan Cengiz, Toshitaka Oohashi, Masafumi Kataoka, Omer Hatipoglu, Kursat Yaykasli, Kenji Shimizu, and Yoshifumi Ninomiya
mRNA expression analysis of ADAMTS-aggrecanases in head and neck cancers
AACR Meeting Abstracts 2007 2007: 554.  

Ingrid Garajova, Pavel Fabian, Rudolf Nenutil, Peter Grell, Ilona Kocakova, Dana Knoflickova, Rostislav Vyzula, and Marek Svoboda
Colon carcinoma and the possible significance of T-cell population, including FOXP3-positive lymphocytes
AACR Meeting Abstracts 2007 2007: 555.  

Kevin Anton, Stephanie Veerasammy, Sonia Picinich, Debabrata Banerjee, and John Glod
LPS-stimulated macrophages induce chemotaxis of mesenchymal stem cells
AACR Meeting Abstracts 2007 2007: 556.  

Pao-Ling Torng, Bor-Ching Sheu, Su-Cheng Huang, Chin-Tarng Lin, and Sheng-Chung Lee
Altered activation of matrix metalloproteinase-2 in human ovarian clear cell carcinoma may correlate with its invasiveness
AACR Meeting Abstracts 2007 2007: 557.  

Ralph Pero, Christopher Lipinski, Nancy Lee, and James Lee
Recruitment and localization of eosinophils to glioma
AACR Meeting Abstracts 2007 2007: 558.  

M. Roomi, Julio Monterrey, Vadim Ivanov, Aleksandra Niedzwiecki, and Matthias Rath
Pattern of MMP-2 and MMP-9 secretion in human cancer cell lines
AACR Meeting Abstracts 2007 2007: 559.  

Ulrike Philippar, Erik Sahai, Jeffrey Wyckoff, Hideki Yamaguchi, Matthew Oser, Silvia Giampieri, Yarong Wang, John Condeelis, and Frank Gertler
Ena/VASP proteins promote cancer cell invasion
AACR Meeting Abstracts 2007 2007: 559A.  

Hiroshi Koyama, Michihiko Harada, Zenzo Isogai, Masahiko Yoneda, Minoru Fujimori, Jun Amano, Reiji Kannagi, Koji Kimata, Shun'ichiro Taniguchi, and Naoki Itano
Hyperproduction of hyaluronan in neu-induced mammary tumor accelerates angiogenesis and lymphangiogenesis through stromal cell recruitment.
AACR Meeting Abstracts 2007 2007: 560.  

Shang-Chiung Chen, Dale Henry, Sameer Gupta, Jian Tan, David Hicks, and Michael Wong
Intravesical PAI-1 inhibits bladder tumor progression by modifying the tumor microenvironment and inhibiting angiogenesis
AACR Meeting Abstracts 2007 2007: 560A.  

Tumor Microenvironment 2: Poster Presentations:Back

JinAh Cho, Pamela Osenkowski, Marta Toth, Huiren Zhao, Seaho Kim, Lucia Schuger, Daniel Bonfil, and Rafael Fridman
The interplay between active and processed MT1-MMP forms influences enzymatic activity, endocytosis, tumor growth and metastasis.
AACR Meeting Abstracts 2007 2007: 561.  

Rosa Hwang, Todd Moore, Thiru Arumugam, Vijaya Ramachandran, and Craig Logsdon
Effect of pancreatic tumor-associated stellate cells on pancreatic tumor growth, metastasis and angiogenesis
AACR Meeting Abstracts 2007 2007: 562.  

Ivy Chung, Adam Karpf, Norma Nowak, Rui-xian Kong, Donald Trump, and Candace Johnson
Tumor-conditioned media induces CYP24 epigenetic silencing and sensitivity to calcitriol in Matrigel-derived endothelial cells (MDEC)
AACR Meeting Abstracts 2007 2007: 563.  

Liz Han, Guillermo Armaiz-Pena, Nicholas Jennings, Aparna Kamat, Yvonne Lin, Williiam Merritt, Charles Landen, Whitney Spannuth, Susan Lutgendorf, and Anil Sood
Characterizing the effects of chronic stress in MMP-9 null background using an orthotopic mouse model of ovarian carcinoma
AACR Meeting Abstracts 2007 2007: 564.  

John Grzesiak and Michael Bouvet
Shifts in the concentrations of extracellular Mg2+ and Ca2+ activate the integrin-mediated malignant phenotype in pancreatic cancer.
AACR Meeting Abstracts 2007 2007: 565.  

Lei Ying, Venkata Kotakadi, Anne Hofseth, Darren Browning, and Lorne Hofseth
Nitric oxide drives retinoblastoma protein hyperphosphorylation and inactivation in the colitis to colon cancer sequence
AACR Meeting Abstracts 2007 2007: 566.  

Daniel Fitzgerald, Diane Palmieri, Eleazar Vega-Valle, Jeanne Herring, and Patricia Steeg
A xenograft model of brain metastasis of breast cancer: metastatic tumors and the brain microenvironment
AACR Meeting Abstracts 2007 2007: 567.  

Neveen Said, Matthew Socha, and Kouros Motamed
Normalization of the ovarian cancer microenvironment by SPARC.
AACR Meeting Abstracts 2007 2007: 568.  

Tenekua Tapia and Ratna Chakrabarti
Modulation of expression of matrix metalloproteinases by LIM kinase 1 in prostate epithelial cells
AACR Meeting Abstracts 2007 2007: 569.  

Robert Cowan, Isabella Mak, Gurmit Singh, and Michelle Ghert
Type I collagenase expression and activity in the osteoblastic stromal cells of giant cell tumor of bone
AACR Meeting Abstracts 2007 2007: 570.  

Kouros Motamed, Neveen Said, Ida Najwer, Matthew Socha, David Fulton, and Samuel Mok
SPARC inhibits LPA-mediated mesothelial-ovarian cancer cell crosstalk.
AACR Meeting Abstracts 2007 2007: 571.  

Pravin Mishra, Prasun Mishra, Rita Humeniuk, John Glod, and Debabrata Banerjee
Mesenchymal stem cells express markers of myofibroblast lineage after long term exposure to conditioned medium from tumor cells
AACR Meeting Abstracts 2007 2007: 572.  

Hui Gao, Rajeth Koneru, John Glod, and Debabrata Banerjee
The JAK2/STAT3- mediated SDF-1/CXCR4 axis promotes mesenchymal stem cell migration in response to the tumor microenvironment.
AACR Meeting Abstracts 2007 2007: 573.  

Junko Horiguchi-Yamada and Hisashi Yamada
Adhesion to the substratum of culture dishes induces the lineage switching of megakaryo-erythroid JAS-R cells.
AACR Meeting Abstracts 2007 2007: 574.  

Siang-Yo Lin, Barton Kamen, Debabrata Banerjee, and John Glod
Hepatoma-derived growth factor is a tumor-derived mesenchymal stem cell chemoattractant
AACR Meeting Abstracts 2007 2007: 575.  

Gabriela Korzus, Lothar Goretzki, Mary Canady, and Mo Saedi
Proteases in Cancer and Inflammation: Novel Bioassays to Measure Their Activities in Complex Biological Samples
AACR Meeting Abstracts 2007 2007: 576.  

Kathleen Nestor, Jonathon Lakins, Nathalie Cohet, Yasuyuki Ohkawa, Jeffrey Nickerson, Anthony Imbalzano, and Valerie Weaver
Flipping the SWI/SNF switch: the influence of chromatin remodeling on mammary epithelial cell behavior
AACR Meeting Abstracts 2007 2007: 577.  

Ana deCarvalho, Jorge Gutierrez, Nancy Lemke, Steven Kalkanis, and Tom Mikkelsen
The expression of the small leucine rich proteoglycan decorin in human gliomas is associated with a subpopulation of neoplastic cells and tumor vasculature in vivo
AACR Meeting Abstracts 2007 2007: 578.  

Karen Bussard and Andrea Mastro
Osteoblast-derived inflammatory cytokines are produced in response to human metastatic breast cancer cells
AACR Meeting Abstracts 2007 2007: 579.  

Qing Sun, Christopher Weber, Marta Toth, Huiren Zhao, Anjum Sohail, Seaho Kim, Jerrold Turner, and Rafael Fridman
Membrane type 6-matrix metalloproteinase (MT6-MMP) is highly expressed in colon cancer and promotes tumor growth of human colon cancer cells in mouse xenografts.
AACR Meeting Abstracts 2007 2007: 580.  

Rebecca Bagley, Shiro Kataoka, Min Yao, Nakayuki Honma, Prashant Nambiar, Cecile Rouleau, Traci Battle, Sharon Morgenbesser, Johanne Kaplan, Bruce Roberts, and Beverly Teicher
Cancer associated fibroblasts from human breast tumors express tumor endothelial marker 1
AACR Meeting Abstracts 2007 2007: 581.  

Nicole Nevadunsky, Joseph Kwong, Ross Berkowitz, and Samuel Mok
Gene expression profile of ovarian stromal fibroblasts in an inflammatory microenvironment
AACR Meeting Abstracts 2007 2007: 582.  

Takaya Matsuzuka, Kathryn Miller, Lara Pickel, Chiyo Doi, and Masaaki Tamura
Angiotensin II and pro-inflammatory cytokines synergistically increased COX-2 mRNA and protein expression in lung fibroblasts.
AACR Meeting Abstracts 2007 2007: 583.  

Yekaterina Khotskaya-Sample, Yuemeng Dai, Yang Yang, and Ralph Sanderson
Syndecan-1 expression is required for robust growth of myeloma tumors in vivo
AACR Meeting Abstracts 2007 2007: 584.  

Hidenobu Kamohara, Takatoshi Ishiko, Teizo Yoshimura, and Hideo Baba
Suppression of DDR1 contributes to cancer progression in mammary carcinoma cells.
AACR Meeting Abstracts 2007 2007: 585.  

Ana Sofia Cachaco, Ana Cristina Santos, and Sergio Dias
Extracellular matrix molecules undergo cell- and type-specific turnover during bone marrow recovery following irradiation: relevance for organ homeostasis and in malignancy
AACR Meeting Abstracts 2007 2007: 586.  

Jennifer Adjodha, Jeffery Lipton, Mark Mittler, and Yuenian Shi
TIMP4 inactivates PTEN and stimulates AKT signaling in human brain tumor and breast cancer cell lines
AACR Meeting Abstracts 2007 2007: 587.  

Leslie Gold, Christine D'Aquino-Ardalan, Jon Lecanda, Patricia Gama, Ashley Fields, and Susan Crawford
Loss of expression and hormonal regulation of pigment epithelium- derived factor (PEDF) in stromal cells: potential role in endometrial carcinogenesis
AACR Meeting Abstracts 2007 2007: 588.  

Mumtaz Rojiani and Amyn Rojiani
Comparative analysis of Thrombospondin-1 silenced H2009 lung carcinoma cells and TIMP-1 overexpressing cells.
AACR Meeting Abstracts 2007 2007: 589.  

Breast, Ovarian, and Lung Cancer Proteomics: Poster Presentations:Back

Deukwoo Kwon, Mahlet Tadesse, Naijun Sha, Ruth Pfeiffer, and Marina Vannucci
Identifying biomarkers from SELDI-TOF MS data of ovarian cancer
AACR Meeting Abstracts 2007 2007: 590.  

Min Ah Yang, Hyun Jin Min, Dong Chun Park, Joo Hee Youn, and Woong Shick Ahn
New serum biomarker discovery in epithelial ovarian cancer using SELDI-TOF technique
AACR Meeting Abstracts 2007 2007: 591.  

Arzu Umar, Huyk Kang, Marion Meijer-van Gelder, Theo Luider, John Foekens, and Ljiljana Pasa-Tolic
Identification of a protein profile predicting tamoxifen-resistance in breast cancer: employing nanoLC-FTICR to analyze laser microdissected tumor cells
AACR Meeting Abstracts 2007 2007: 592.  

Darrell Ellsworth, Erin Seeley, Rachel Ellsworth, Brenda Deyarmin, Melinda Sanders, Jeffrey Hooke, Richard Caprioli, and Craig Shriver
Protein expression profiles generated by histology-directed MALDI-TOF differ in primary breast carcinomas from patients with versus without axillary lymph node metastasis
AACR Meeting Abstracts 2007 2007: 593.  

Charlotte Clarke, TuAnh Dang, Donna Badgwell, Eric Fung, and Robert Bast
Proteomics discovery of urinary biomarkers for early stage ovarian cancer
AACR Meeting Abstracts 2007 2007: 594.  

Hyun Jin Min, Eun Kyeong Oh, Jeong Namkoong, Kyung Tai Kim, Young Jae Kim, Hae Nam Lee, Yong Wook Kim, and Woong-Shick Ahn
New Ovarian Cancer Biomarker Discovery Using Two-Dimensional Gel Analysis
AACR Meeting Abstracts 2007 2007: 595.  

Waleed Abdel-Aziz, Derek Hoelz, Srilakshmi Alagharu, Robert Hickey, and Linda Malkas
Identification of altered isoforms of poly(ADP-ribose) polymerase-1 (PARP-1) in breast cancer cells
AACR Meeting Abstracts 2007 2007: 596.  

Ashwin Narayana, Maksym Yezhelyev, Xiaohu Gao, Ahmad Al_Hajj, Tongrui Liu, TiJi Philip, and Ruth O'Regan
Optimization of quantitative analysis of multicolor QD-based biomolecular profiling of tumor.
AACR Meeting Abstracts 2007 2007: 597.  

Nandini Raghuraman, Craig Rowell, Mark Carpenter, and Coral Lamartiniere
Prepubertal exposure to bishenol A alters RAD51 expression in the mammary proteome of sprague-dawley rats
AACR Meeting Abstracts 2007 2007: 598.  

Lacey Dobrolecki, Jeremy Flanagan, Leanne Budde, Sarah Dutkevitch, Robert Goulet, Susan Clare, Anna Maria Storniolo, and Robert Hickey
Proteomic analysis of serum from women with and without unilateral invasive ductal carcinoma
AACR Meeting Abstracts 2007 2007: 599.  

Padma Tadi-Uppala, Carlos Garberoglio, Larry Beeson, Kumar Kolli, Patrick Grof-Tisza, Alisha Preuss, David Kirchner, Michael Liebman, Helen Kim, Gurunatha Uppala, Gurinder Dhindsa, John Morgan, Susanne Montgomery, and Sharon Lum
Biomarkers for breast cancer in African American women
AACR Meeting Abstracts 2007 2007: 600.  

Martijn van der Werff, Mirre de Noo, Bart Mertens, Hans Dalebout, Marco Bladergroen, Andre Deelder, and Rob Tollenaar
MALDI-TOF serum protein profiling for the detection of breast cancer using independent validation
AACR Meeting Abstracts 2007 2007: 601.  

BINGYUN SUN, Jeffrey Ranish, Biaoyang Lin, and Leroy Hood
Quantitative glycoproteomics using a novel shotgun glycopeptide-capture approach coupled with mass spectrometry for analysis of ovarian cancer chemoresistance
AACR Meeting Abstracts 2007 2007: 602.  

Ming Lu, Stephen Whelan, Jianbo He, Kym Faull, Julian Whitelegge, Romaine Saxton, and Helena Chang
Analysis of serum and nipple aspirate fluid (NAF) from breast cancer patients by liquid chromatography and mass spectrometry
AACR Meeting Abstracts 2007 2007: 603.  

Atsuhiko Toyama, Takashi Shimada, Tetsuyoshi Sugita, Yutaka Aoki, Chikage Aoki, Yukari Umino, Atsushi Suzuki, Daisuke Aoki, Yataro Daigo, Yusuke Nakamura, and Takaaki Sato
Comprehensive proteomic studies on ovarian cancer and biomarker discovery for molecular tumor typing
AACR Meeting Abstracts 2007 2007: 604.  

Leasa Greene, Sarah Schwartz, Sarah Dallas, Patricia Veno, and Lynda Bonewald
Targeted proteomics analysis of EGFP expressing metastatic breast cancer cells using mass spectrometry.
AACR Meeting Abstracts 2007 2007: 605.  

Bae Ji-Yeon, Dong Hyun Kim, Wonshik Han, Cheolju Lee, and Dong-Young Noh
Novel protein markers identified by tissue fraction technique comparing estrogen receptor negative- against positive-breast cancer cells and tissues
AACR Meeting Abstracts 2007 2007: 606.  

Lewis Pannell, Brandon Metge, Flaubert Mbeunkui, and Lalita Shevde
Profiling differentially secreted biomarkers in the MCF10 isogenic breast cancer cell lines for biomarker discovery
AACR Meeting Abstracts 2007 2007: 607.  

TAKU NAKAGAWA, Sharon Huang, Steve Martinez, Andy Tran, David Elashoff, Xing Ye, Roderick Turner, Armando Giuliano, and Dave Hoon
Proteomic profiling of primary breast cancer predicts axillary lymph node metastasis
AACR Meeting Abstracts 2007 2007: 608.  

Brian Balgley, Weijie Wang, Natini Jinawath, Li Yang, Cheng Lee, and Ie-Ming Shih
Discovery and validation of recurrent, drug-resistant serous epithelial ovarian carcinoma biomarkers in a mouse model coupled with targeted and mass spectrometry-based proteomic studies
AACR Meeting Abstracts 2007 2007: 609.  

Jeffrey Borgia, Casey Frankenberger, L. Faber, Kelly Kaiser, Shannon McCormack, Philip Bonomi, and John Coon
Discovery of serum biomarkers for squamous cell lung carcinoma using novel proteomic methods
AACR Meeting Abstracts 2007 2007: 610.  

Jung-eun Kim, Kyung Hee Koo, Pil-Sun Shin, and Yun Park
Discovery of putative lung cancer biomarkers from secretome of the cells mimicking human lung carcinogenesis
AACR Meeting Abstracts 2007 2007: 611.  

Klarisa Rikova, Ailan Guo, Qingfu Zeng, Anthony Possemato, Herbert Haack, Julie Nardone, Kimberly Lee, Cynthia Reeves, Yu Li, Laura Sullivan, Randy Wetzel, Joan MacNeill, John Kornhauser, John Rush, Roberto Polakiewicz, and Michael Comb
Phosphorylation signatures identify tyrosine kinases activated in lung cancer
AACR Meeting Abstracts 2007 2007: 612.  

Kyung Hee Koo, Jung Eun Kim, and Yun Park
Comparative proteomic analysis of human lung cancer in different types and stages
AACR Meeting Abstracts 2007 2007: 613.  

Elizabeth Joseloff, Kim Rosenthal, Chad Danis, Tao He, Jenny Heidbrink, William FitzHugh, Candy Lee, Karen Van Orden, Steve Ruben, and Paul Moore
The use of mass spectrometry based proteomics to identify cell surface proteins applicable for monitoring drug resistance, response and therapeutic targeting
AACR Meeting Abstracts 2007 2007: 614.  

William Cho, Joseph Au, Tai-Tung Yip, Christine Yip, Timothy Yip, Wai-Wai Cheng, Stella Cheung, John Chan, C.C. Ma, K.M. Ko, K.K. Ho, and Stephen Law
Evaluation of the plasma and serum biomarkers for lung cancer using SELDI-TOF MS
AACR Meeting Abstracts 2007 2007: 615.  

William Cho, Joseph Au, Tai-Tung Yip, Christine Yip, Stella Cheung, John Chan, C.C. Ma, K.M. Ko, K.K. Ho, and Stephen Law
SELDI-TOF MS fingerprintings as a novel reference pattern to distinguish cancer tissue from noncancer tissue in female nonsmoking adenocarcinoma patients in Hong Kong
AACR Meeting Abstracts 2007 2007: 616.  

Charles Birse, Mehdi Mesri, Elizabeth Joseloff, Erin Brand, Tao He, Aiqun Li, Gordon Nicol, Kim Alving, David Parmelee, Ahn Nguyen, Linda Wang, Karen Van Orden, David Tanenbaum, Marcia Lewis, Paul Moore, and Steve Ruben
Lung cancer biomarkers identified through mass spectrometry-based proteomic discovery from tissue and cell lines
AACR Meeting Abstracts 2007 2007: 617.  

Won-A Joo, Seth Hoffman, Hsin-Yao Tang, Anil Vachani, Steven Albelda, and David Speicher
Discovery and validation of multiple lung cancer serological biomarkers by combining a 4-D proteomics strategy with a xenograft mouse model
AACR Meeting Abstracts 2007 2007: 618.  

Cancer Cell Cycles: Oral Presentations - Invited Abstracts:Back

Rosalie Sears-Pelz and Hugh Arnold
Signaling pathways that regulate the c-Myc oncoprotein
AACR Meeting Abstracts 2007 2007: SY06-01.  

Cancer Targets and Drug Screening: Poster Presentations:Back

Sanjay Awasthi, Sharad Singhal, Jyotsana Singhal, Sushma Yadav, Kenneth Drake, and Yogesh Awasthi
Regression of lung and colon cancer xenografts by depleting or inhibiting RLIP76
AACR Meeting Abstracts 2007 2007: 619.  

Osamu Kondoh, Christian Tovar, Shannon Hamilton, Ann Hoffman, David Heimbrook, and Lyubomir Vassilev
An optimized screen for mitotic inhibitors using cancer cells synchronized at the G2/M phase border
AACR Meeting Abstracts 2007 2007: 620.  

Paul Northcott, Yukiko Nakahara, Paul Kongkham, John Peacock, Lars Feuk, Sunil Rao, Wiesia Grajkowska, Boleslaw Lach, Richard Grundy, Yancey Gillespie, Carlos Carlotti, Frederick Boop, Darell Bigner, Ian Pollack, Ronald Hamilton, Richard Gilbertson, Steven Scherer, James Rutka, and Michael Taylor
High-resolution copy number analysis identifies novel tumor suppressor genes and pathways in medulloblastoma
AACR Meeting Abstracts 2007 2007: 621.  

Natalia Costa, Nuno Mendes, Nuno Marcos, Paula Paulo, Tom Caffrey, Michael Hollingsworth, and Filipe Santos-Silva
Relevance of MUC1 mucin variable number of tandem repeats polymorphism in Helicobacter pylori adhesion to gastric epithelial cells
AACR Meeting Abstracts 2007 2007: 622.  

Huaiyu Ma, Tapas Das, Suzette Pereira, Xiao-Ming Li, Zhijian Yang, Shigeo Yagi, Pradip Mukerji, and Robert Hoffman
Efficacy of dietary antioxidants combined with a chemotherapeutic agents on human colon cancer in a fluorescent orthotopic mouse model
AACR Meeting Abstracts 2007 2007: 623.  

Tatjana Mijatovic, Isabelle Roland, Eric Van Quaquebeke, Bo Nilsson, Anne Mathieu, Frank Van Vynckt, Vincenzo Facchini, Francis Darro, Gustavo Blanco, and Robert Kiss
The alpha-1 subunit of the sodium pump could represent a novel target to combat non-small-cell lung cancers (NSCLCs)
AACR Meeting Abstracts 2007 2007: 624.  

Jinming Gu, Archana Reddy, Arthur Young, and William Kaelin
EglN prolyl hydroxylase regulates cyclin D1 in mammary development and cancer
AACR Meeting Abstracts 2007 2007: 625.  

Mathias Schmidt, Klaus Pekari, Thomas Baer, Karl Sanders, Astrid Leja, Werner Stuermer, Volker Gekeler, and Thomas Beckers
A chemical biology approach for the identification of novel mitosis-specific inducers of apoptosis
AACR Meeting Abstracts 2007 2007: 626.  

Norie Yoshioka, Hiroko Kishikawa, and Guo-fu Hu
Role of angiogenin in Akt-induced prostate intraepithelial neoplasia
AACR Meeting Abstracts 2007 2007: 627.  

David Modrak, Kristen Mattei, Evelyn Leon, David Goldenberg, and David Gold
Sphingomyelin increases drug sensitivity in human pancreatic cancer cells in vitro and in vivo.
AACR Meeting Abstracts 2007 2007: 628.  

Valia Mihaylova, Allison Green, Oliver Semmes, and Gary Kupfer
Human T cell leukemia virus I tax1 protein sensitizes p53 mutant cells to DNA damage
AACR Meeting Abstracts 2007 2007: 629.  

Martin Smollich, Martin Gotte, Christian Kersting, Johannes Aebi, Jeanett Fischgrabe, Isabel Radke, Ludwig Kiesel, and Pia Wulfing
The Endothelin-Converting Enzyme-1 (ECE-1) as a novel target in breast cancer therapy
AACR Meeting Abstracts 2007 2007: 631.  

Said Goueli, Kevin Hsiao, Marina Zdanovskaia, and Jolanta Vidugiriene
Homogenous, luminescent HTS-formatted technologies for cAMP-, and cGMP-dependent phosphodiesterases (PDEs)
AACR Meeting Abstracts 2007 2007: 632.  

Gerhard Kelter, Thomas Metz, Jutta Fehr, Andre Korrat, Thomas Greiner, Julia Schuler, and Heinz-Herbert Fiebig
Discovery of novel anticancer agents using panels of hematological and non-hematological human tumor cell lines
AACR Meeting Abstracts 2007 2007: 633.  

Lothar Goretzki, Jue Wang, and Mo Saedi
Microtiter plate assays for the assessment of biochemical activities of E2 and E3 ubiquitin enzymes
AACR Meeting Abstracts 2007 2007: 634.  

Sean Sissons, Karen Cox, Jeremy Graff, Bruce Konicek, Rebecca Lynch, and Frederick Chadwell
Development of a sandwich ELISA for quantitation of eIF-4E in ASO treated pre-clinical samples
AACR Meeting Abstracts 2007 2007: 635.  

Thomas Pfister, Ralph Parchment, Joseph Tomaszewski, James Doroshow, and Robert Kinders
Development of a quantitative immunoassay for measurement of topoisomerase I covalent complex as a pharmacodynamic marker for the effect of anti-cancer drugs.
AACR Meeting Abstracts 2007 2007: 636.  

Ting-Chao Chou and Nick Martin
The mass-action law-based new computer software, CompuSyn, for automated simulation of synergism and antagonism in drug combination studies
AACR Meeting Abstracts 2007 2007: 637.  

Jun-ichi Nezu, Shinta Kobayashi, Eri Hashimoto, Noriaki Sawada, Masakazu Hasegawa, Yuko Aoki, and Kunihiro Hattori
Identification of CDCP1 as a novel molecular target of anti-cancer therapeutic antibody targeting prostate cancer
AACR Meeting Abstracts 2007 2007: 638.  

Etgar Levy-Nissenbaum, Frank Alexis, Benjamin A. Teply, Judy Cheng, Frank X. Gu, Aleksandar F. Radovic-Moreno, Robert Langer, and Omid C. Farokhzad
Isolation of novel RNA aptamers against prostate cancer for targeted drug delivery
AACR Meeting Abstracts 2007 2007: 639.  

Ahmed Boucharaba
The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases formation in breast cancer
AACR Meeting Abstracts 2007 2007: 640.  

Vladimir Khazak, Natalia Skobeleva, Sanjay Menon, Lutz Weber, and Erica Golemis
In vitro and in vivo synergy of MCP compounds with MAPK pathway inhibitors, taxanes and vinca-alkaloid compounds
AACR Meeting Abstracts 2007 2007: 641.  

Lei Zhang, Kelly Huber, Helen Evans, Abhik Mukherjee, Paulam Patel, and Stewart Martin
Targeting the thioredoxin system for breast cancer treatment
AACR Meeting Abstracts 2007 2007: 642.  

Brittney Jung, Weixiong Zhong, and Nihal Ahmad
Sirtuin histone deacetylases SIRT1 and SIRT2 as novel targets for the management of prostate cancer
AACR Meeting Abstracts 2007 2007: 643.  

Jose Thaiparambil, Bernard Gary, Adam Keeton, Yulia Maxuitenko, Gregory Gorman, Lori Coward, Robert Reynolds, and Gary Piazza
Sulindac sulfide selectively inhibits cGMP PDE from human HT-29 colon tumor cells
AACR Meeting Abstracts 2007 2007: 644.  

Vernon Alvarez
Studies with long random phage libraries: Epitope-specific peptides recapitulate antibody complementarity determining regions (CDRs) of PSMA and MUC-1 antibodies and PSMA binding peptides target prostate xenografts
AACR Meeting Abstracts 2007 2007: 645.  

Stephanie Zaugg, Amy Aulthouse, Elaine Fedon, and David Kinder
Antitumor activity of celecoxib in the HT-29 colon carcinoma cell line using a three dimensional agarose cell culture method
AACR Meeting Abstracts 2007 2007: 646.  

Karyn Ho, Meng Shi, Armand Keating, and Molly Shoichet
Targeted co-delivery of trastuzumab and Interleukin-2 for breast cancer immunotherapy
AACR Meeting Abstracts 2007 2007: 647.  

Experimental Antibodies and Proteins: Poster Presentations:Back

Amelia D'Alessio, Antonella De Luca, Monica Maiello, Adele Carotenuto, Anna Maria Rachiglio, Marianna Gallo, Maria Napolitano, and Nicola Normanno
The combination of gefitinib and trastuzumab affects cell cycle distribution and expression of cell cycle regulatory proteins in breast cancer cells
AACR Meeting Abstracts 2007 2007: 648.  

Kathryn Parsons, Lisa Crocker, Douglas Leipold, Ginny Li, Janet Tien, Debra Dugger, Gail Lewis Phillips, Sarajane Ross, Jay Tibbitts, and Mark Sliwkowski
Trastuzumab directed cytotoxic therapy: Efficacy against HER2-positive trastuzumab-insensitive breast cancer models and enhanced response in trastuzumab-sensitive models
AACR Meeting Abstracts 2007 2007: 649.  

Christel Larbouret, Bruno Robert, Isabelle Navarro-Teulon, Simon Thezenas, Maha-Zohra Ladjemi, Sebastien Morisseau, Frederic Bibeau, Jean-Pierre Mach, Andre Pelegrin, and David Azria
In vivo therapeutic synergism of anti-EGFR and anti-HER2 monoclonal antibodies against pancreatic carcinomas
AACR Meeting Abstracts 2007 2007: 650.  

Thomas Friess, Werner Scheuer, and Max Hasmann
Antitumour activity of trastuzumab combined with various agents targeting HER-family receptors in HER2-positive xenografts progressing under trastuzumab monotherapy
AACR Meeting Abstracts 2007 2007: 651.  

Marie Prewett, Christopher Damoci, Rajiv Bassi, Dale Ludwig, Daniel Hicklin, and James Tonra
IMC-A12 enhances the efficacy of cetuximab + gemcitabine therapy in human pancreatic carcinoma xenografts.
AACR Meeting Abstracts 2007 2007: 652.  

Junya Fukai, Kazuko Sakai, Hideharu Kimura, Junichiro Kuroda, Tomoya Fukui, Makoto Kawaishi, Terufumi Kato, Fumiko Taguchi, Hideyuki Yokote, Toru Itakura, Fumiaki Koizumi, and Kazuto Nishio
Anti-tumor activity of cetuximab in malignant glioma cells overexpressing deletion mutant EGFR variant III
AACR Meeting Abstracts 2007 2007: 653.  

Nicholas Nicolaides, Luigi Grasso, Wolfgang Ebel, Rina Patel, Eric Routhier, Yuhong Zhou, Raffit Hassan, Martin Phillips, and Philip Sass
MORAb-009, a monoclonal antibody that specifically targets mesothelin, a cell surface tumor adhesion molecule over-expressed in pancreatic, ovarian, and lung cancer and mesothelioma.
AACR Meeting Abstracts 2007 2007: 654.  

Min Li, Uddalak Bharadwaj, Rongxin Zhang, Sheng Zhang, Hong Mu, Changyi Chen, and Qizhi Yao
Mesothelin: a malignant factor and novel therapeutic vaccine target for pancreatic cancer
AACR Meeting Abstracts 2007 2007: 655.  

Albina Nesterova, Paul Carter, and Leia Smith
Glypican-3 as a novel target for an antibody-drug conjugate
AACR Meeting Abstracts 2007 2007: 656.  

Suzanne Coberly, Jennifer Rojko, Yan Chen, Adam Cunha, Mark Armanini, Gordon Vehar, and Jennie Mather
RAV12 cross reactivity with human normal and tumor tissues
AACR Meeting Abstracts 2007 2007: 657.  

Damon Meyer, Tim Bovee, Svetlana Doronina, Ruth Moser, Jane Schmidt, Peter Senter, and Dennis Benjamin
Determining relative Tubulin binding affinity in an Auristatin library
AACR Meeting Abstracts 2007 2007: 658.  

Yaolin Wang, Philip Lipari, Xiaoying Wang, Tracy Chen, Jenny Liu, Cindy Marrinan, Stacey Taylor, Suining Lee, Lianzhu Liang, Judith Hailey, Lynn Wang, Michael Malkowski, Cynthia Seidel-Dugan, Brian Long, Ming Liu, and Yan Wang
SCH 717454, a fully human monoclonal antibody against human IGF-1R, inhibits tumor growth in xenograft models
AACR Meeting Abstracts 2007 2007: 659.  

Christine Fazenbaker, Karen Coffman, Kathy Mulgrew, Melissa Damschroder, Peter Kiener, Steven Coats, Rob Woods, Changshou Gao, William Dall'Acqua, Herren Wu, and Elizabeth Bruckheimer
Potent antibody dependent cellular cytoxicity activity against human tumor cells using a humanized anti-EphA2 Antibody
AACR Meeting Abstracts 2007 2007: 660.  

Ezogelin Oflazoglu, Ivan Stone, Kristine Gordon, Iqbal Grewal, Che-Leung Law, and Hans-Peter Gerber
Characterization of Fc-mediated effector functions of SGN30 in vitro and in vivo
AACR Meeting Abstracts 2007 2007: 661.  

Daad Sayegh, Terence Lee, Mitra Amoozgar, Nives Ceric, Luis da Cruz, Susan Hahn, Daniel Pereira, Ronnie Poon, and David Young
Novel antibody ARH460-16-2 recognizes an epitope of CD44 that is highly expressed in liver cancers
AACR Meeting Abstracts 2007 2007: 662.  

Jenny Peterschmitt, Tobias Bauerle, Franz Armbruster, and Martin Berger
Combined treatment with zoledronic acid and an anti-BSP antibody not only inhibits the growth of skeletal osteolytic lesions induced by MDA-MB-231GFP human breast cancer cells in nude rats but also favours skeletal remineralization.
AACR Meeting Abstracts 2007 2007: 663.  

Ming-Hai Wang, Hang-Ping Yao, Lin-Fang Chen, Yi Lu, and Kun Zhang
Therapeutical potentials of the monoclonal antibody Zt/2F2 for the malignant epithelial cancers overexpressing the RON receptor tyrosine kinase*
AACR Meeting Abstracts 2007 2007: 664.  

Santiago Aparo, Leandro Cerchietti, Ana Antun, Rita Shaknovich, and Ari Melnick
Targeting BCL6 with a specific cell permeable inhibitor results in anti-tumor activity in diffuse large B-cell lymphoma pre-clinical models.
AACR Meeting Abstracts 2007 2007: 665.  

Yoshio Yoshida, Tetuji Kurokawa, Fumikazu Kotsuji, and Hynda K Kleinmann
Laminin-1-derived AG73 peptide inhibited formation of multicellular spheroids of free-floating ovarian cancer cells
AACR Meeting Abstracts 2007 2007: 666.  

Carolina Abramovich, Earnest Leung, Lola Maksumova, Yan Zhao, Lisa Garcia, and Hassan Salari
Characterization of the anti-metastatic activity of a SDF-1 peptide analog in different tumor models.
AACR Meeting Abstracts 2007 2007: 667.  

Hernan Farina, Yasser Perera, Ignacio Hernandez, Osmany Mendoza, Joem Serrano, Osvaldo Reyes, Daniel Gomez, Roberto Gomez, Boris Acevedo, Daniel Alonso, and Silvio Perea
Systemic administration of a protein kinase (CK2) peptide inhibitor reduces solid tumor growth in mice.
AACR Meeting Abstracts 2007 2007: 668.  

Alice Taylor, Evelyn Leon, and David Goldenberg
A peptide antagonist of heparin-binding sites of both placenta growth factor and Flt-1 inhibits tumor growth and metastasis in an orthotopic model of breast cancer.
AACR Meeting Abstracts 2007 2007: 669.  

Eva Schmelz, Hu Xu, Jianhua Du, Sanjeev Banerjee, Fazlul Sarkar, Arun Rishi, and Adhip Majumdar
EGF-receptor related protein (ERRP) causes regression of early and intermediate stages of colorectal cancer
AACR Meeting Abstracts 2007 2007: 670.  

Seiji Adachi, Tomokazu Nagao, Satoshi To, Frederick Maxfield, Levy Kopelovich, and I Weinstein
(-)-Epigallocatechin Gallate (EGCG) causes internalization of the epidermal growth factor receptors (EGFR) in SW480 colon cancer cells.
AACR Meeting Abstracts 2007 2007: 671.  

Michal Ayalon-Soffer, Zohar Tiran, Anat Oren, Hagit Amitai, Judith Horev, Ilan Tsarfaty, Noam Shani, and Galit Rotman
Novel soluble splice variants of the c-Met receptor are potent antagonists of the HGF/Met pathway, and display anti-tumorigenic activity
AACR Meeting Abstracts 2007 2007: 672.  

Tiefu Liu, Jiaozhong Cai, Denise Gibo, and Waldemar Debinski
A variant of interleukin 13 fused to diphtheria toxin is selectively cytotoxic to glioblastoma multiforme cells
AACR Meeting Abstracts 2007 2007: 673.  

Mario Filion, Olivier Raguin, Caroline Mignard, Benoit Filion, Francis Bichat, and Nigel Phillips
Anticancer activity of mycobacterial cell wall-DNA complex (MCC) in a model of rat colon cancer peritoneal carcinomatosis
AACR Meeting Abstracts 2007 2007: 674.  

Yoon Lee, Tina Avolio, Ningping Feng, Keyong Xiong, Hongnan Jin, Ming Wang, Jim Wright, and Aiping Young
Determination of optimized administration schedule of GTI-2040 and docetaxel combination treatment for NSCLC cells in vitro and in vivo
AACR Meeting Abstracts 2007 2007: 675.  

Philip Kasprzyk, Ann Nelson, Yeelana Shen, Jundong Zhang, Jennifer Morgan, Lynda Cooper, John Taylor, and Jesse Dong
Regressions and tumor free survival with a novel targeted camptothecin-somatostatin conjugate
AACR Meeting Abstracts 2007 2007: 676.  

Laura Strong, Mark Shahan, John Kink, Baigen Mei, Kerry Ervin, and Ronald Raines
Pre-clinical toxicology for a potent anti-cancer agent, a human ribonuclease variant
AACR Meeting Abstracts 2007 2007: 677.  

HDAC Inhibitors 1: Poster Presentations:Back

Sriram Balasubramanian, Jason Ramos, Mint Sirisawad, Louie Naumovski, and Joseph Buggy
Mechanisms of sensitivity in primary hematopoietic tumors and tumor lines to a novel HDAC inhibitor PCI-24781.
AACR Meeting Abstracts 2007 2007: 678.  

Aakanksha Khandelwal, Aashvini Belosay, Lalji Gediya, and Vincent Njar
HDAC inhibitor (MS-275) enhances the anticancer activity of a retinoic acid metabolism blocking agent (VN/66-1) in human prostate cancer models
AACR Meeting Abstracts 2007 2007: 679.  

Rafael Erlich, Alexander Guminski, Danny Rickwood, and Nicholas Saunders
Valproic acid as a therapeutic agent for head and neck squamous cell carcinomas
AACR Meeting Abstracts 2007 2007: 680.  

Min-Yu Chen, Yinhua Yu, Zhen Lu, Gary Rosner, Edward Atkinson, Siquing Fu, John Kavanagh, and Robert Bast
Synergistic inhibition of ovarian cancer cell growth with demethylating agents and histone deacetylase inhibitors
AACR Meeting Abstracts 2007 2007: 681.  

Shabana Shabbeer, Madeleine Kortenhorst, Sushant Kachhap, Nathan Galloway, and Michael Carducci
The anti-angiogenic effect of histone deacetylase inhibitors interfere with DNA methyl transferase inhibitor activity in vivo in prostate cancer models
AACR Meeting Abstracts 2007 2007: 682.  

Melissa LaBonte, Peter Wilson, William Fazzone, Heinz-Josef Lenz, and Robert Ladner
The effects of histone deacetylase inhibitors on epidermal growth factor receptor expression in colon cancer cell lines: implications for combination therapy.
AACR Meeting Abstracts 2007 2007: 683.  

Philip Jones, Sergio Altamura, Fabrizio Colaceci, Odalys Gonzalez Paz, Olaf Kinzel, Laura Llauger Bufi, Giuseppe Mesiti, Edith Monteagudo, Giovanna Pescatore, Michael Rowley, Maria Verdirame, and Christian Steinkuhler
Development of a novel series of potent and selective histone deacetylase inhibitors with efficacy in vivo
AACR Meeting Abstracts 2007 2007: 684.  

Mari Peltola, Kristiina Iljin, Maija Wolf, Henrik Edgren, Santosh Gupta, Sami Kilpinen, Matthias Nees, and Olli Kallioniemi
Histone deacetylase inhibition as a potential therapeutic in ERG-positive prostate cancer
AACR Meeting Abstracts 2007 2007: 685.  

Hao Cheng, William Jones, Xiaohui Wei, Zhongfa Liu, Dasheng Wang, Samuel Kulp, Ching-Shih Chen, Joseph Covey, and Kenneth Chan
Preclinical pharmacokinetics studies of R- and S- enantiomers of the histone deacetylase inhibitor, HDAC-42 (NSC 731438), in the rat
AACR Meeting Abstracts 2007 2007: 686.  

Marielle Dejligbjerg, Ib Christensen, Morten Grauslund, Peter Jensen, and Maxwell Sehested
Gene expression screen in cell panel selected for varying sensitivity towards the Histone DeACetylase inhibitor (HDACi) PXD101 reveals potential predictors of HDACi sensitivity
AACR Meeting Abstracts 2007 2007: 687.  

Douglas Marchion, Elona Bicaku, Morgen Schmitt, and Pamela Munster
Modulation of chromatin dynamics by selective depletion of HDAC2
AACR Meeting Abstracts 2007 2007: 688.  

Shambhunath Choudhary and Hwa-Chain Wang
Oncogenic H-ras facilitates apoptosis induced by histone deacetylase inhibitors in human urinary bladder cancer cells
AACR Meeting Abstracts 2007 2007: 689.  

Diane Palmieri, Julie Bronder, Robert Weil, Andreas Stark, Sean Davis, Eleazar Vega-Valle, Jeanne herring, Toshiyuki Yoneda, Raffael Kurek, H. Maximilian Mehdorn, Paul Meltzer, and Patricia Steeg
Preclinical studies in support of the use of Vorinostat (SAHA) for the treatment of brain metastases of breast cancer
AACR Meeting Abstracts 2007 2007: 690.  

Xiaozhong Qian, Evan Mills, William LaRochelle, Henri Lichenstein, and Michael Jeffers
Activity of PXD101, an HDAC inhibitor, used alone or in combination with 5-FU in preclinical gastroesophageal studies
AACR Meeting Abstracts 2007 2007: 691.  

William Fazzone, Eva Borucka, Heinz-Josef Lenz, and Robert Ladner
Histone deacetylase inhibitors downregulate thymidylate sythnase expression and interact synergistically with fluoropyrimidines in colon cancer cell lines
AACR Meeting Abstracts 2007 2007: 692.  

Tamer Fandy, Anchalee Jiemjit, Hetty Carraway, Stephen Baylin, James Herman, and Steven Gore
Decitabine-induced apoptosis is p53-independent and mediated through reactive oxygen species (ROS) production and caspase activation
AACR Meeting Abstracts 2007 2007: 693.  

Jennifer Roth, Susan Korenchuk, Theresa Zhang, Andrey Loboda, James Hardwick, Elizabeth Harrington, Victoria Richon, and Valeria Fantin
Mechanisms of in vitro acquired resistance to vorinostat (suberoylanilide hydroxamic acid, SAHA)
AACR Meeting Abstracts 2007 2007: 694.  

Peggy Olive, Adriana Banuelos, and Judit Banath
Radiosensitization by the HDAC inhibitor PCI-24781 in SiHa and WiDr human tumor cell lines
AACR Meeting Abstracts 2007 2007: 695.  

Brigette Ma, Fion Sung, Qian Tao, Jason H. T. Wong, Gulshan Ara, Winnie Yeo, and Anthony Chan
The effect of the histone deacetylase inhibitor (HDACi) PXD101 on cell growth and expression of viral and host genes in hepatitis B virus (HBV)-carrying hepatocellular carcinoma (HCC) cell lines
AACR Meeting Abstracts 2007 2007: 696.  

Clifton Dalgard, Jon Yang, Kurt van Quill, and Joan O'Brien
Histone deacetylase inhibitors for therapy of retinoblastoma
AACR Meeting Abstracts 2007 2007: 697.  

Anna Scuto, Mark Kirschbaum, Agnes Juhasz, Leo Kretzner, Stephen Forman, Yun Yen, and Richard Jove
Novel HDAC inhibitor, LBH589, potently blocks growth of Ph-negative acute lymphoblastic leukemia (ALL) cells and induces expression of DNA damage response genes
AACR Meeting Abstracts 2007 2007: 698.  

Valeria Fantin, Andrey Loboda, Jennifer Roth, Cloud Paweletz, Sophia Randolph, James Hardwick, Jacqueline Pierce, Elizabeth Harrington, Ronald Hendrickson, John Reilly, Christopher Ware, Marshall Kadin, Madeleine Duvic, Stanley Frankel, and Victoria Richon
High expression and persistent activation of STAT1, 3 and 5 predicts resistance to the histone deacetylase (HDAC) inhibitor vorinostat (suberoylanilide hydroxamic acid, SAHA) in cutaneous T cell lymphoma cells.
AACR Meeting Abstracts 2007 2007: 699.  

Gary Scott, Corina Marx, Crystal Berger, Stefan Schafer, Manfred Jung, and Christopher Benz
Inhibition of HuR-associated cytosolic histone deacetylase (HDAC) destabilizes ERBB2 transcripts and inhibits breast cancer cell growth.
AACR Meeting Abstracts 2007 2007: 700.  

Francesca Bruzzese, Monia Rocco, Alessandra Leone, Geny Piro, Antonio Avallone, Elena Di Gennaro, and Alfredo Budillon
Synergistic antitumor interaction between histone deacetylase inhibitor vorinostat and topoisomerase I inhibitor topotecan in small cell lung cancer (SCLC) cells
AACR Meeting Abstracts 2007 2007: 701.  

Sabine Haecker, Klaus-Michael Debatin, and Simone Fulda
Histone deacetylase inhibitors overcome resistance of caspase-8 negative cancers to TRAIL-induced apoptosis by upregulating caspase-8
AACR Meeting Abstracts 2007 2007: 702.  

Rekha Rao, Bryan Herger, Warren Fiskus, Rajeshree Joshi, Kapil Bhalla, and Angela Hatter
Combination of histone deacetylase 6/heat shock protein 90 inhibition and bortezomib: a strategy to enhance ER-based UPR-mediated cytotoxicity in human mantle cell lymphoma cells
AACR Meeting Abstracts 2007 2007: 703.  

Andre Fedier, Konstantin Dedes, Patrick Imesch, Andre von Bueren, and Daniel Fink
Generation of histone deacetylase (HDAC) inhibitor-resistant cell lines: A novel, multidrug resistance-independent resistance phenotype.
AACR Meeting Abstracts 2007 2007: 704.  

Yen-Shen Lu, Yoko Kashida, Jui-Hsiang Hung, Chang-Shi Chen, Yu-Chieh Wang, Ann-Lii Cheng, and Ching-Shih Chen
In vivo efficacy of OSU-HDAC42, a novel phenylbutyrate-based histone deacetylase inhibitor, in human hepatocellular carcinoma animal models
AACR Meeting Abstracts 2007 2007: 705.  

Thomas Muhlenberg, Jonathan Fletcher, Siegfried Seeber, and Sebastian Bauer
Histone deacetylase-inhibitors in gastrointestinal stromal tumor (GIST): therapeutic potential
AACR Meeting Abstracts 2007 2007: 706.  

Janice Gabrilove, Melanie McConnell McConnell, Windy Berkofsky-Fessler, Sanjay Sharma, Lewis Silverman, Luis Isola, John Mandeli, Andres Sirulnik, and Jonathan Licht
Divalproex sodium in relapsed or refractory acute myeloid leukemia alters histone acetylation and gene expression
AACR Meeting Abstracts 2007 2007: 707.  

DNA Methylation/Epigenetics: Ruth Sager Memorial Symposium on Cancer Genetics and Epigenetics: Oral Presentations - Invited Abstracts:Back

Kornelia Polyak
DNA methylation profiles as markers of stemness
AACR Meeting Abstracts 2007 2007: SY07-01.  

New and Emerging Targets 1: Poster Presentations:Back

Jennifer Hsing, David McConkey, and Craig Logsdon
GRP78 and HSP90 are overexpressed in pancreatic cancer
AACR Meeting Abstracts 2007 2007: 708.  

Shobhan Gaddameedhi and Satadal Chatterjee
Association between the Unfolded Protein Response (UPR) and hypersensitivity to cisplatin: a mechanistic study employing molecular genomics
AACR Meeting Abstracts 2007 2007: 709.  

Yair Gazitt, James Freeman, Kolaparthi Venkatasubbarao, Gene Rose, Chris Takimoto, and Anthony Tolcher
Targeted therapy for osteosarcoma using 17AAG and rapamycin: Characterization of induced apoptosis and inhibition of mTOR and AKT/MAP kinase pathways
AACR Meeting Abstracts 2007 2007: 710.  

Danyelle Townsend, Larry Keefer, Joseph Saavedra, Christopher Pazoles, and Kenneth Tew
Drug mediated oxidative or nitrosative stress induces the unfolded protein response
AACR Meeting Abstracts 2007 2007: 711.  

Yonghua Yang and Kapil Bhalla
Identification and role of lysine acetylation sites in regulating chaperone function of heat shock protein 90{alpha}.
AACR Meeting Abstracts 2007 2007: 712.  

Yun-Han Lee, Taro Takami, Jeonghoon Heo, Anita Ton, Elizabeth Conner, Ju-Seog Lee, Valentina Factor, and Snorri Thorgeirsson
Therapeutic targeting of COP1, a negative regulator of p53 and c-Jun, in hepatocellular carcinoma
AACR Meeting Abstracts 2007 2007: 713.  

Craig Leach, Dana Francis, Roland Hilgarth, Alejandro Bernal, Michael Mattern, Tauseef Butt, and Benjamin Nicholson
Discovery of USP2 inhibitors using a novel isopeptidase assay
AACR Meeting Abstracts 2007 2007: 714.  

Ruea-Yea Huang, David Kowalski, Hans Minderman, Nishant Gandhi, and Erica Johnson
SUMO pathway is a major determinant of doxorubicin cytotoxicity in yeast
AACR Meeting Abstracts 2007 2007: 715.  

Fangting Wu, Susanna Chiocca, William Beck, and Yin-Yuan Mo
Gam1-induced inhibition of sumoylation associated with alterations of drug responsiveness through activation of apoptosis pathways
AACR Meeting Abstracts 2007 2007: 716.  

Ashok Purandare, Honghe Wan, Naomi Laing, Wayne Vaccaro, John Tokarski, and Michael Poss
Discovery & SAR of lactam based boronic acid derivatives as inhibitors of 20S-proteasome
AACR Meeting Abstracts 2007 2007: 717.  

Christopher Smolock, Paul Foley, James Pippin, and Jeffrey Drebin
Targeting beta-catenin in human chronic myelogenous leukemia cells
AACR Meeting Abstracts 2007 2007: 718.  

Arunashree Bhamidipati, Keith Chan, Daryl Taketa, Uyen Nguyen, David Voehringer, and Irving Weissman
Post-translational modification of β-Catenin as a molecular classification marker in colorectal cancer: insight into Wnt signaling in tumor stem cells
AACR Meeting Abstracts 2007 2007: 719.  

Suman Kambhampati, Kakali Dhar, Gibananda Ray, Snigdha Banerjee, Peter Van Veldhuizen, and Sushanta Banerjee
Involvement of β-catenin-E-cadherin in the inhibition of Barrett’s esophageal adenocarcinoma growth by 2-methoxyestradiol.
AACR Meeting Abstracts 2007 2007: 720.  

Sanford Barsky, Yi Xiao, and Yin Ye
Targeting up-regulated notch signaling in the CD133+ stem cells within the protected niche of the lymphovascular embolus of inflammatory breast cancer
AACR Meeting Abstracts 2007 2007: 721.  

Andrea Basso, Lei Chen, Craig Webb, Maureen Laverty, Lissette Nale, Linda James, Eric Gustafson, and Diane Levitan
Gene correlates of SCH66336 (Lonafarnib), a farnesyl transferase inhibitor, sensitivity and resistance in tumor cell lines.
AACR Meeting Abstracts 2007 2007: 722.  

Mario Vega, Melisa Martinez-Paniagua, Berenice Sanchez-Arellano, Bernardo Martinez-Miguel, Alejandro Avilez-Salas, Rogelio Hernandez-Pando, Cesar Gonzalez-Bonilla, Ali Jazirehi, Sara Huerta-Yepez, and Benjamin Bonavida
Activation of the p38MAPK signaling pathway and over-expression of Bcl-2/Bcl-XL in patients with DLBCL: potential biomarkers and targets for therapeutics. A Mexican Lymphoma Group Study
AACR Meeting Abstracts 2007 2007: 723.  

jun chen, sha jin, steven tahir, Haichao Zhang, saul rosenberg, steve elmore, and chris Tse
The coordinated neutralization of Bcl-XL and Mcl-1 by ABT-737 in combination with radiation treatment leads to enhanced cytotoxicity in NSCLC cells
AACR Meeting Abstracts 2007 2007: 724.  

Xiongwen Zhang, Yan Zhang, Ping Min, Guangfeng Wang, Xinyan Ni, Liquang Lou, Nathalie Bruey-Sedano, and Dajun Yang
Synergistic inhibition of tumor growth by combined treatment with the pan Bcl-2 inhibitor AT-101 and docetaxel in human cancer xenograft models
AACR Meeting Abstracts 2007 2007: 725.  

Haichao Zhang, Jun Chen, Zhui Chen, Sha Jin, Paul Nimmer, Stephen Tahir, Morrey Smith, Yu Xiao, Saul Rosenberg, Steve Elmore, and Chris Tse
The Bcl-2 family protein inhibitor, ABT-263, broadly potentiates the cytotoxicity of other therapeutic agents in vitro
AACR Meeting Abstracts 2007 2007: 726.  

Morey Smith, Chris Tse, Joy Bauch, Ryan Fryer, Laurie Iciek, Kennan Marsh, Sherry Morgan, Richard Nelson, Glenn Reinhart, Saul Rosenberg, and Steven Elmore
In vivo hematological effects of Bcl-2 family protein inhibitors in dogs
AACR Meeting Abstracts 2007 2007: 727.  

Pharmacogenomics: Poster Presentations:Back

Ji-Youn Han, Hyeong-Seok Lim, Sung Young Lee, Heung Tae Kim, and Jin Soo Lee
Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer
AACR Meeting Abstracts 2007 2007: 728.  

Joseph Gligorov, Frederic Selle, Eric Levy, Karine Beerblock, Pierre Saintigny, Daniele Avenin, Jean-Pierre Lotz, Keyvan Rezai, Jean-Francois Bernaudin, Serge Uzan, Pierre Levy, Francois Lokiec, and Anne Fajac
ABCB1 (MDR1) genotype in relation to doxorubicin and docetaxel pharmacokinetics in patients with breast cancer
AACR Meeting Abstracts 2007 2007: 729.  

Phillip Muller, Heike Dally, Cornelia Klappenecker, Lutz Edler, Birgit Jager, Martina Gerst, Bertold Spiegelhalder, Siegfried Tuengerthal, Jurgen Fischer, Peter Drings, Helmut Bartsch, and Angela Risch
Polymorphisms in ABCG2, ABCC3 and CNT1 and their possible impact on lung cancer chemotherapy
AACR Meeting Abstracts 2007 2007: 730.  

Balram Chowbay, Suman Lal, Zee Wan Wong, Xiao Chen Shu, Liu Yan Yan, Viknesvaran Selvarajan, Srinivas Rao Jada, and London Lucien Ooi
MDR1 and ABCG2 polymorphisms and influence on doxorubicin pharmacokinetics in Asian breast cancer patients
AACR Meeting Abstracts 2007 2007: 731.  

Alain Nganga, Kristie Engler, Candace Johnson, Donald Trump, Lionel Coignet, and Josephia Muindi
CYP24A1 polymorphisms and splicing variants associated with different patterns of vitamin D metabolism in human cancer cell lines
AACR Meeting Abstracts 2007 2007: 732.  

Miluse Hubackova, Radka Vaclavikova, Roman Kodet, Marcela Mrhalova, Ivan Gut, and Pavel Soucek
Role of quinone oxidoreductase (NQO1, NQO2) genes in prediction and therapy of breast cancer
AACR Meeting Abstracts 2007 2007: 733.  

Je-Hwan Lee, Seong-Gil Ryu, Seong-Jun Choi, Jung-Hee Lee, Young-Shin Lee, Miee Seol, Eun-Hye Hur, Soo Han Lee, Kyun Seop Bae, Gyu Jeong Noh, Moo-Song Lee, SungCheol Yun, Sang Beom Han, and Kyoo Hyung Lee
Influence of glutathione S-transferase T1 (GSTT1) gene polymorphism on the pharmacokinetics of intravenous busulfan
AACR Meeting Abstracts 2007 2007: 734.  

Rui Gao, Douglas Price, Eddie Reed, and William Figg
Variant DNA repair genes occur infrequently in African Americans: Implications for different clinic response to platinum chemotherapy
AACR Meeting Abstracts 2007 2007: 735.  

Federico Innocenti, Snezana Mirkov, Ramamoorthy Nagasubramanian, Jacqueline Ramirez, Wanqing Liu, Kathleen Hennessy, Soma Das, M. Eileen Dolan, Edwin Cook, and Mark Ratain
Effect of the Werner's syndrome gene variant 4330T>C on the cytotoxicity of camptothecin in lymphoblastoid cell lines
AACR Meeting Abstracts 2007 2007: 736.  

Xin Ye, Wanqing Liu, Emma Thompson, Elisa Cerri, Mark Lingen, and Federico Innocenti
A common promoter polymorphism in the vascular endothelial growth factor receptor 2 gene (KDR) affects gene transcriptional activity
AACR Meeting Abstracts 2007 2007: 737.  

L'Aurelle Johnson, Paul Orchard, K. Baker, Qing Cao, Xinjing Wang, Erica Langer, Sheiren Farag-El Maasah, Julie Ross, Rory Remmel, and Pamala Jacobson
Pharmacogenetics of busulfan in pediatric patients undergoing hematopoietic cell transplantation (HCT)
AACR Meeting Abstracts 2007 2007: 738.  

Rong Huang, Shiwei Duan, Emily Kistner, Wasim Bleibel, Tyson Clark, Tina Chen, Anthony Schweitzer, John Blume, Nancy Cox, and M. Eileen Dolan
Genetic variants contributing to differences in chemotherapy-induced cytotoxicity in cell lines derived from CEPH and the Yoruban populations
AACR Meeting Abstracts 2007 2007: 739.  

Joseph Ciccolini, Laetitia Dahan, Alexandre Evrard, Caroline Raynal, Adrien Ortiz, Sarah Giacometti, Fleur Franceschini, Aurore Blesius, Aude Le Goffic, Nicolas Andre, Gerard Milano, Roger Favre, Jean-Francois Seitz, and Cedric Mercier
Toxic-death case upon gemcitabine/carboplatin administration: probable implication of cytidine deaminase gene polymorphism
AACR Meeting Abstracts 2007 2007: 740.  

Caroline Raynal, Cedric Mercier, Joseph Ciccolini, Jean-Christophe Boyer, Dominique Joubert, Frederic Hollande, Serge Lumbroso, Jean-Paul Brouillet, and Alexandre EVRARD
Screening of sequence variations of the cytidine deaminase (CDA) gene by high resolution melting in gemcitabine-treated patients
AACR Meeting Abstracts 2007 2007: 741.  

Daniela Ramos, Jorge Gaspar, Marta Pingarilho, Octavia Gil, Jose Rueff, and Nuno Oliveira
DNA damage induced by doxorubicin is not associated with individual GSTM1 and GSTT1 polymorphisms
AACR Meeting Abstracts 2007 2007: 742.  

Min Guan, Lijun Zhu, George Somlo, Alison Hughes, Bingsen Zhou, and Yun Yen
Expression of wild type or specific mutations of FGFR3 in multiple myeloma cells is associated with variable PS-341 therapeutic effects
AACR Meeting Abstracts 2007 2007: 743.  

Woo Sun Kwon, Sun Young Rha, Yeon Ho Choi, Jung Ok Lee, Kyu Hyun Park, Jae Joon Jung, Tae Soo Kim, Joong Bae Ahn, Hei-Cheul Jeung, and Hyun Cheol Chung
Ribonucleotide reductase M1 (RRM1) 2464G>A polymorphism shows an association with gemcitabine chemosensitivity in cancer cell lines
AACR Meeting Abstracts 2007 2007: 744.  

Araba Adjei, Tarek Abouel Leil, Chiaki Endo, Grace Dy, Oreste Salavaggione, Joel Reid, Sumithra Mandrekar, Julian Molina, Matthew Ames, and Alex Adjei
Functional polymorphisms in the human Folylpolyglutamate Synthase (FPGS) gene may influence efficacy and/or toxicity of Pemetrexed
AACR Meeting Abstracts 2007 2007: 745.  

John Deeken, Trena Cormier, Douglas Price, Seth Steinberg, Karen Tran, David Liewehr, Paul Hardenbol, William Dahut, Xin Miao, and W Figg
Pilot test of a new genotyping platform, the Affymetrix Drug Metabolizing Enzymes and Transporter (DME-T) Panel, for cancer and pharmacogenomic research
AACR Meeting Abstracts 2007 2007: 746.  

Sandra Beare, Alan Boddy, Joyce Nutt, Kieran O'Toole, and John Lunec
Influence of thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms on clinical outcome of patients with early breast cancer after adjuvant treatment with CMF
AACR Meeting Abstracts 2007 2007: 747.  

Sophie Rowbotham, Gareth Veal, Ann Daly, Chris Redfern, Gordon Taylor, and Alan Boddy
Metabolism of 13-cis retinoic acid by CYP2C8 and its polymorphic forms
AACR Meeting Abstracts 2007 2007: 748.  

Preclinical Radiotherapeutics: Poster Presentations:Back

Meredith Morgan, Leslie Parsels, Laura Kollar, Jonathan Maybaum, and Theodore Lawrence
The integration of EGFR inhibitors with gemcitabine-radiation therapy for pancreatic cancer.
AACR Meeting Abstracts 2007 2007: 749.  

Farukh Durrani, Shousong Cao, Young-Mee Park, Gail Thompson, Joyce Martin, Gary Yang, Michael Kuettel, and Youcef Rustum
Synergistic effect of selenium compounds with radiation therapy in human A549 lung xenografts
AACR Meeting Abstracts 2007 2007: 750.  

Woo-Young Kim, Seung-Hyun Oh, and Ho-Young Lee
Deguelin can sensitize the radioresistant cells through blocking HIF-1 and angiogenesis.
AACR Meeting Abstracts 2007 2007: 751.  

Jeffrey Albert, Carolyn Cao, Kwang Woon Kim, Ling Geng, Alan Sandler, David Johnson, and Bo Lu
Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models
AACR Meeting Abstracts 2007 2007: 752.  

Russell Hales, Julie Schwaninger, Haoming Zhou, Arthur Burnett, and Theodore DeWeese
Radiation induced neuronal cell death is modulated by immunophilin ligand GPI-1046
AACR Meeting Abstracts 2007 2007: 753.  

Jimmie Colon, Sudipta Seal, Santhi Konduri, Arati Limaye, Maen Abdelrahim, and Cheryl Baker
Selective radioprotection of normal tissues by new cerium oxide nanoparticles
AACR Meeting Abstracts 2007 2007: 754.  

Rolf Barth
Thymidine kinase 1 as a molecular target for neutron capture therapy of brain tumors
AACR Meeting Abstracts 2007 2007: 755.  

Wei Qiu, Eleanor Carson-Walter, Lin Zhang, and Jian Yu
PUMA regulates intestinal stem cell radiosensitivity
AACR Meeting Abstracts 2007 2007: 756.  

Ishiwata Yoshiro, Kenshiro Shiraishi, Keiichi Nakagawa, Shoji Yokochi, Chiho Taruki, Teruo Akuta, Mariko Ishihara, Takuya Tamatani, Shiro Kanegasaki, and Kouji Matsushima
ECI301, a derivative of MIP-1{alpha} enhances the efficacy of radiation and induces an abscopal effect in tumor-bearing mice
AACR Meeting Abstracts 2007 2007: 757.  

Han-Xiang An, Christiane Schroter, Haitao He, Emmanouil Fokas, Hans-Otto Neidel, Michael Bieker, Frank Rose, and Rita Engenhart-Cabillic
Inhibition of Wnt signaling pathway enhances radiation-induced apoptosis in breast cancer cells
AACR Meeting Abstracts 2007 2007: 758.  

Bea Pauwels, Natasja Taelemans, Greet Pattyn, Hilde Lambrechts, Christel De Pooter, Filip Lardon, and Jan Vermorken
The radiosensitizing effect of gemcitabine: further research on the apoptotic pathway of radiosensitisation
AACR Meeting Abstracts 2007 2007: 759.  

Naoyuki Saito, Dawn Woods, and Shaomeng Wang
Evaluation of a non-peptide Smac mimetic as a potent radiosensitizer of human non-Hodgkins lymphoma cell lines
AACR Meeting Abstracts 2007 2007: 760.  

Maurizio Marangolo, Francesca Fanini, Livia Turci, Ermanno Emiliani, Giuseppe Monti, Luciana Ricci Curbastro, and Francesco Fabbri
Concomitant or sequential alimta (MTA) and radiotherapy (RXT) in human pancreatic cancer cell lines-a preclinical experience
AACR Meeting Abstracts 2007 2007: 761.  

Laurent Quero, Nicole Giocanti, Christophe Hennequin, and Vincent Favaudon
Evaluation of concomitant or neoadjuvant association between bicalutamideTM and irradiation in prostate cancer cells.
AACR Meeting Abstracts 2007 2007: 762.  

Florence Huguet, Nicole Giocanti, Christophe Hennequin, and Vincent Favaudon
Radiosensitization by STI571 in human chronic myelogenous leukaemia K562 cells : a story of cell cycle modulation
AACR Meeting Abstracts 2007 2007: 763.  

Monica Maffi, Jean Louis Fischel, Federica Tonissi, Gerard Milano, Marco Merlano, and Cristiana Lo Nigro
Impact of erythropoietin (EPO) on irradiation effect on the EPO receptor positive head and neck cancer
AACR Meeting Abstracts 2007 2007: 764.  

Topoisomerase I and II Inhibitors: Poster Presentations:Back

Jun Ohwada, Masao Tsukazaki, Satoshi Niizuma, Hitomi Suda, Takeshi Murata, Sawako Ozawa, Mika Endoh, Eitaro Nanba, Kotaro Ogawa, Kazuo Kobayashi, Hisafumi Okabe, and Nobuo Shimma
Discovery of a new topoisomerase I inhibitor, TP300: A pH-dependently activated water-soluble prodrug
AACR Meeting Abstracts 2007 2007: 765.  

Devasis Chatterjee, Carl Graeber, Jun Wang, James Darnowski, Claudio Pisano, and Y. Chin
Inhibition of Stat3 activation by the camptothecin analog ST2617 in human cancer cells
AACR Meeting Abstracts 2007 2007: 766.  

Anna Rogojina and John Nitiss
Cytotoxic single strand damage generated by topoisomerase II targeting agents
AACR Meeting Abstracts 2007 2007: 767.  

Mika Endo, Masako Ura, Hiromi Tanimura, Yoko Miyazaki, Masao Tsukazaki, Nobuo Shimma, Hisafumi Okabe, and Masanori Miwa
Development of a new DNA topoisomerase I inhibitor, TP300: A pH-activated water-soluble prodrug
AACR Meeting Abstracts 2007 2007: 768.  

Omari Bandele and Neil Osheroff
Bioflavonoids as poisons of human topoisomerase II{alpha} and β
AACR Meeting Abstracts 2007 2007: 769.  

Hong Zhu, Min Huang, Yi Chen, Ze-Hong Miao, Yu-Jun Cai, and Jian Ding
R16, a novel amonafide analogue, induces G2 arrest and apoptosis via poisoning topoisomerase II
AACR Meeting Abstracts 2007 2007: 770.  

Leslie Kurtzberg, Traci Battle, Cecile Rouleau, Rebecca Bagley, Naoki Agata, Min Yao, Steven Schmid, Stephanie Roth, Jennifer Crawford, Roy Krumbholtz, Xian-Jie Yu, Fei Wang, Edmond LaVoie, and Beverly Teicher
Bone marrow and tumor line cytotoxicity and human tumor xenograft efficacy of non-camptothecin and camptothecin Topoisomerase-I inhibitors
AACR Meeting Abstracts 2007 2007: 771.  

Hung Huynh, Pierce Chow, and Khee Chee Soo
Combination therapy with the MEK inhibitor AZD6244 (ARRY-142886) and doxorubicin enhances growth suppression and apoptosis in an HCC model
AACR Meeting Abstracts 2007 2007: 772.  

Michel Tautu, Daniele Montaudon, Francesca De Giorgi-Ichas, Francois Ichas, and Philippe Pourquier
Cellular interaction between DNA topoisomerase I and DNA-PKcs and its potential role in the sensitivity to camptothecin.
AACR Meeting Abstracts 2007 2007: 773.  

Bo Zhang, Qinjie Wen, Wei Lv, Bo Yang, and Qiaojun He
Anti-proliferative effect of CPT-21 on gastric cancer cell SGC-7901 both in vitro and in vivo
AACR Meeting Abstracts 2007 2007: 774.  

Joseph Deweese and Neil Osheroff
Isolating topoisomerase II-mediated DNA cleavage using 3'-bridging phosphorothiolates
AACR Meeting Abstracts 2007 2007: 775.  

Claudio Pisano, Loredana Vesci, Rosanna Fodera, Fabiana Fosca Ferrara, Mario Guglielmi, Federica Bucci, Concetta Aulicino, Angelo Marconi, Patrizia Tobia, Paolo Carminati, Giovanni Luca Beretta, Michelandrea De Cesare, and Franco Zunino
Identification and pharmacological characterization of ST1968, a new camptothecin derivative
AACR Meeting Abstracts 2007 2007: 776.  

Marie van der Merwe and Mary-Ann Bjornsti
Topoisomerase I architecture is a determinant of camptothecin sensitivity
AACR Meeting Abstracts 2007 2007: 777.  

Claudio Pisano, Loredana Vesci, Rosanna Fodera, Fabiana Fosca Ferrara, Sergio Penco, Paolo Carminati, Lucio Merlini, Michelandrea De Cesare, and Franco Zunino
Antitumor activity of ST1968, a novel topoisomerase I inhibitor
AACR Meeting Abstracts 2007 2007: 778.  

Weijun Wang, Alex Ghandi, Leonard Liebes, and Thomas Chen
Direct conversion of Irinotecan to SN-38 by malignant gliomas: an intracranial model
AACR Meeting Abstracts 2007 2007: 779.  

V. Ashutosh Rao, Keli Agama, Susan Holbeck, Jerry Collins, and Yves Pommier
Batracylin, 8-aminoisoindolo [1,2-b]quinazolin-10(12H)-one, a dual inhibitor of topoisomerases I and II in early clinical trials: molecular mechanism and biomarkers of action.
AACR Meeting Abstracts 2007 2007: 780.  

Alex Yurkovetskiy, Mikhail Papisov, Alan Fischman, Alex Hiller, Mao Yin, James Rolke, S Harrison, Robin Ball, K Sheridan, Beth Hollister, Cheryl Napier, Ullrich Schwertschlag, Peter Leone, Julie Olson, and Russell Petter
MER-1001, a novel polymeric prodrug of camptothecin, is a potent inhibitor of LS174 and A2780 human tumor xenografts in a mouse model
AACR Meeting Abstracts 2007 2007: 781.  

Eriko Toyoda, Shigehide Kagaya, Kazuya Okamoto, Hideki Koyama, Noritaka Adachi, and Kiyohiro Nishikawa
NK314 is a topoisomerase II{alpha} specific inhibitor inducing stable cleavage complex and rapid DNA double strand breaks.
AACR Meeting Abstracts 2007 2007: 782.  

mariefrance poupon, Franck Assayag, Ludmilla DePlater, Elisabetta Marangoni, and Veronique Dieras
In vivo efficacy of gimatecan, a Novartis new topoisomerase 1 inhibitor alone or combined with RAD001, bevacizumab or erlotinib in breast, lung and ovary human cancer xenografts.
AACR Meeting Abstracts 2007 2007: 783.  

Xing Wu, Hong Liang, Kimberley O'Hara, Jack Yalowich, and Brian Hasinoff
Effects of the organic mercury compound thimerosal on human erythroleukemic K562 and colon carcinoma HCT116 cell growth and on inhibition of human topoisomerase II
AACR Meeting Abstracts 2007 2007: 784.  

Ryan Bender, Amy Ham, and Neil Osheroff
Quinone metabolites of environmental toxins as topoisomerase II poisons
AACR Meeting Abstracts 2007 2007: 785.  

Timothy Madden, Mary Johansen, Charles Conrad, Reza Kazerooni, Izabela Fokt, Neil Thapar, Colin Meyer, and Waldemar Priebe
WP769:An orally bioavailable topo II poison with activity against brain tumors
AACR Meeting Abstracts 2007 2007: 786.  

Stephane Leonce, Amelie Lansiaux, Laurence Kraus-Berthier, Stephanie Giraudet, Marie-Helene David-Cordonnier, Patrick Hautefaye, Gilbert Lavielle, John Hickman, and A Pierre
High stability of the cleavage complex induced by novel non-lactone camptothecin derivatives
AACR Meeting Abstracts 2007 2007: 787.  

Daniele Montaudon, Komaraiah Palle, Laurent Rivory, Jacques Robert, Celine Douat-Casassus, Stephane Quideau, Mary-Ann Bjornsti, and Philippe Pourquier
Vicinal cysteines 504 and 505 are critical for DNA topoisomerase I poisoning by thiol-reactive compounds and camptothecin
AACR Meeting Abstracts 2007 2007: 788.  

Maria Vittoria Fogli, Laura Baranello, Francesca Ferri, Yves Pommier, and Giovanni Capranico
DNA topoisomerase I (Top1) can regulate the coupling of RNA polymerase II (RNAP) pausing at promoter-proximal sites and transcript maturation in human cells.
AACR Meeting Abstracts 2007 2007: 789.  

Behavioral and Social Science in Cancer / Early Detection and Prevention Research: Poster Presentations:Back

Yong Cui, Xu Wang, Margaret Hargreaves, Wanqing Wen, and Robert Levine
Factors associated with participation, initial quit and six-month relapse in a smoking cessation program for veterans
AACR Meeting Abstracts 2007 2007: 790.  

Elijah Okegbile, Anta'Sha Jones, Gary Johanning, and Clinton Grubbs
Chemopreventive effect of antioxidants on SK-OV-3 tumor-forming ovarian epithelial cancer cells
AACR Meeting Abstracts 2007 2007: 792.  

Alrena Lightbourn and Clement Gwede
Self-reported motivations and barriers to prostate cancer screening among black men in Hillsborough County, Florida
AACR Meeting Abstracts 2007 2007: 793.  

Sai Potukuchi, Prem Agarwal, and Ravi Kant
Metabolic Syndrome as a risk factor for breast cancer: A pilot study
AACR Meeting Abstracts 2007 2007: 794.  

Ann Hamilton and Myles Cockburn
Exploring new measures of socio-demographic factors associated with later stage of cancer diagnosis
AACR Meeting Abstracts 2007 2007: 795.  

Shaheenah Dawood, Kristine Broglio, Shu-Wan Kau, Gabriel Hortobagyi, and Massimo Cristofanilli
Prognostic value of body mss index (BMI) in locally advanced breast cancer (LABC)
AACR Meeting Abstracts 2007 2007: 796.  

Yoshikatsu Koga, Hisayuki Matsushita, Masahiro Yasunaga, Hideo Baba, and Yasuhiro Matsumura
Improved isolation of exfoliated cells from feces for noninvasive diagnosis of colorectal cancer: A comparative study of new immuno-magnetic beads
AACR Meeting Abstracts 2007 2007: 797.  

Pierre Lao-Sirieix, Brian Rous, Maria O'Donovan, Irene Debiram, Richard Hardwick, and Rebecca Fitzgerald
Non-endoscopic immunocytological screening test for Barrett’s oesophagus
AACR Meeting Abstracts 2007 2007: 798.  

Wenli Dong, Donald Berry, Therese Bevers, Shu-Wan Kau, Limin Hsu, Richard Theriault, and Yu Shen
Prognostic role of detection method in breast cancer: M. D. Anderson Cancer Center experience
AACR Meeting Abstracts 2007 2007: 799.  

Onouchi Shigeki, Yasuhiro Matsumura, Hirotoshi Hasegawa, Hideki Nishibori, Yoshiyuki Ishii, Takashi Endoh, and Masaki Kitajima
Newly colorectal cancer screening method based on SSCP analysis of DNA from exfoliated colonocytes in naturally evacuated feces
AACR Meeting Abstracts 2007 2007: 800.  

Jaak Janssens and Kris Motmans
Preclinical experience with the automated large core biopsy device based on a helix and rotational cutting for breast cancer prevention.
AACR Meeting Abstracts 2007 2007: 801.  

Clemens Prinsen, Niels Cremers, Corne Klaassen, Adriaan Tan, Luc Strobbe, Theo Ruers, and Frederik Thunnissen
Analysis of human DNA in fecal samples; is it useful in colorectal cancer screening?
AACR Meeting Abstracts 2007 2007: 802.  

Denise Laronde, Greg Hislop, P Williams, Catherine Poh, Samson Ng, and Miriam Rosin
Oral cancer screening knowledge and practices among community dentists: A pilot project
AACR Meeting Abstracts 2007 2007: 803.  

Madhuri Vemuru and Surya ML
A study of the risk factors for breast cancer in India: a case control study
AACR Meeting Abstracts 2007 2007: 804.  

Atul Juneja
Cervical cancer screening options in a developing country like India
AACR Meeting Abstracts 2007 2007: 805.  

Aglaya Iyevleva, Anna Sokolenko, Maxim Rozanov, Natalia Mitiushkina, Natalia Sherina, Elena Chekmariova, Konstantin Buslov, Evgeny Shilov, Alexandr Togo, Elena Bit-Sava, Dmitry Voskresenskiy, Oleg Chagunava, Peter Devilee, Cees Cornelisse, Vladimir Semiglazov, and Evgeny Imyanitov
Founder mutations in early-onset, familial and bilateral breast cancer patients from Russia
AACR Meeting Abstracts 2007 2007: 806.  

Zora Djuric, Jianwei Ren, Katherine Radakovich, Glee VanLoon, Nora DiLaura, and Ananda Sen
Design and implementation of a self-selected mediterranean diet
AACR Meeting Abstracts 2007 2007: 807.  

Chris Bajdik, Steve Sung, John Spinelli, David Huntsman, Gallinger Steven, Horsman Douglas, and Gallagher Richard
Predicting the performance of a genetic testing service for cancer susceptibility
AACR Meeting Abstracts 2007 2007: 808.  

Nicole Lockhart, Jimmie Vaught, Julie Schneider, Ian Fore, Helen Moore, John Gillespie, Elizabeth Scott, Anna Barker, and Carolyn Compton
NCI's first generation guidelines for biospecimen resources
AACR Meeting Abstracts 2007 2007: 809.  

Claudine Kavanaugh, Paula Trumbo, and Kathleen Ellwood
U.S. Food and Drug Administration’s scientific evidence-based review system for health claims
AACR Meeting Abstracts 2007 2007: 810.  

faina linkov, Alex Lisovich, Zoya Yurkovetsky, Adele Marrangoni, Lyudmila Velikokhatnaya, Brian Nolen, Matthew Winans, William Bigbee, Jill Siegfried, Anna Lokshin, and Robert Ferris
Early detection of head and neck cancer: development of a novel screening tool using multiplexed immunobead-based biomarker profiling
AACR Meeting Abstracts 2007 2007: 811.  

Immunotherapy: Oral Presentations - Invited Abstracts:Back

ENA Wang and Francesco Marincola
"Spontaneous" and induced rejection of human cancer
AACR Meeting Abstracts 2007 2007: SY08-01.  

Thomas Waldmann
IL-15 in the life and death of lymphocytes: Implications for cancer therapy and vaccine design
AACR Meeting Abstracts 2007 2007: SY08-02.  

Biomarkers of DNA Damage and Repair 1: Poster Presentations:Back

Silvia Balbo, Paolo Boffetta, Sarolta Gundy, Mingyao Wang, and Stephen Hecht
Quantitation of N2-ethylidenedeoxyguanosine in human leukocyte DNA and its relationship to alcohol consumption.
AACR Meeting Abstracts 2007 2007: 812.  

Jinguo Chen, Antai Wang Wang, Stephanie Spernak, Yuelin Zhu, Ramona Dumitrescu, Francoise Seillier-Moiseiwitsch, Sean David, and Peter Shields
Alterations of gene expression profiles of human lymphocytes by cigarette smoke
AACR Meeting Abstracts 2007 2007: 813.  

Stefan Tyroller and Wolfgang Zwickenpflug
Identification of 3’-hydroxymyosmine in urine of smokers and non-smokers
AACR Meeting Abstracts 2007 2007: 814.  

Qingshan Qu, Xiaomei Li, Feiyun An, Lanzeng Liu, Guang Jia, Hiroko Meserve, Karen Koenig, Beverly Cohen, Max Costa, Nirmal Roy, Roy Shore, Mianhua Zhong, LungChi Chen, Shuhua Liu, and Lei Yan
Cr(VI) exposure and biomarkers: Cr in erythrocytes in relation to exposure and polymorphisms of genes encoding anion transport proteins
AACR Meeting Abstracts 2007 2007: 815.  

Shuguang Leng, Amanda Bernauer, Randall Willink, Maria Picchi, Christine Stidley, Frank Gilliland, Richard Crowell, and Steven Belinsky
Double strand break repair capacity is associated with promoter methylation index in a high-risk cohort for lung cancer
AACR Meeting Abstracts 2007 2007: 816.  

Brock Christensen, Jennifer Longacker, Carmen Marsit, E Houseman, Heather Nelson, John Godleski, Raphael Bueno, David Sugarbaker, and Karl Kelsey
Asbestos burden, epigenetic silencing, and survival in malignant pleural mesothelioma
AACR Meeting Abstracts 2007 2007: 817.  

Baitang Ning, Zhongning Lin, Xuemei zhang, Jinsheng Tuo, Yongli Guo, Bridgett Green, Chi-Chao Chan, Wen Tan, Wenhua Ling, Fred Kadlubar, and Dongxin Lin
Variant of the Cockayne syndrome B gene ERCC6 confers risk of lung cancer
AACR Meeting Abstracts 2007 2007: 818.  

Matthew Bonner, Margaret DiVita, Min Shen, Chin-San Liu, Xingzhou He, and Qing Lan
Polycyclic aromatic hydrocarbon-laden smoky coal exposure, mitochondrial DNA copy number and the risk of lung cancer.
AACR Meeting Abstracts 2007 2007: 819.  

Su Jia, Niu Rungui, Liu Li, Han Xiaoyou, Zhao Baoxing, Shi Jianping, Li Jiawei, Wei Guorong, Chen Chuanwei, Mu Lina, and Zhang Zuofeng
The DNA repair gene XRCC1/LIG1 polymorphism and risk of lung cancer in a Chinese population
AACR Meeting Abstracts 2007 2007: 820.  

Zhibin Hu, Haifeng Wang, Minhua Shao, Guangfu Jing, Weiwei Sun, Yi Wang, Hongliang Liu, Ying Wang, Hongxia Ma, Ji Qian, Li Jin, Qingyi Wei, Daru Lu, Wei Huang, and Hongbing Shen
Genetic variants in MGMT and risk of lung cancer in southeastern Chinese: a haplotype-based analysis
AACR Meeting Abstracts 2007 2007: 821.  

Carmen Marsit, Eugene Houseman, Kim Kraunz, Michael McClean, and Karl Kelsey
DNA hypermethylation and homozygous deletion are distinct molecular phenotypes in head and neck squamous cell carcinoma
AACR Meeting Abstracts 2007 2007: 822.  

Rita Velikina, Hal Morgenstern, Sander Greenland, Donald Tashkin, Jeanette Papp, Wendy Cozen, Thomas Mack, Yuan-Chin Amy Lee, Anh Le, and Zuo-Feng Zhang
A population-based case-control study of the association between DNA repair genes XPC and MLH1 and head and neck cancer
AACR Meeting Abstracts 2007 2007: 823.  

Meng Chen, Jian Gu, Maosheng Huang, H. Grossman, Colin Dinney, and Xifeng Wu
High-order interactions among genetic polymorphisms in nucleotide excision repair pathway genes and smoking in modulating bladder cancer risk
AACR Meeting Abstracts 2007 2007: 824.  

Maosheng Huang, Colin Dinney, Xin Lin, Jie Lin, H. Grossman, and Xifeng Wu
High-order interactions among genetic variants in DNA Base Excision Repair (BER) pathway genes and smoking in bladder cancer susceptibility
AACR Meeting Abstracts 2007 2007: 825.  

Ananya Choudhury, Faye Elliott, Robert Bristow, D. Bishop, and Anne Kiltie
Molecular epidemiology of DNA repair signalling proteins as a risk factor for bladder cancer.
AACR Meeting Abstracts 2007 2007: 826.  

Simon Spivack and Weiguo Han
Lung carcinogenesis tracked by DNA methylation mapping from exhaled breath of ambulatory subjects.
AACR Meeting Abstracts 2007 2007: 827.  

Mary Coolbaugh-Murphy, Jingping Xu, Crystal Simien, Louis Ramagli, Barry Brown, Noralane Lindor, Stephen Gallinger, Robert Haile, Daniela Seminara, Patrick Lynch, Marsha Frazier, and Michael Siciliano
Small pool PCR (SPPCR) makes microsatellite instability (MSI) a biomarker for identifying genetic risk in normal tissues of HNPCC MSI-high families and in tumors of patients thought microsatellite stable.
AACR Meeting Abstracts 2007 2007: 828.  

Frederica Perera, Shuang Wang, Stephen Chanock, Wei-Yann Tsai, and Deliang Tang
Gene-environment interactions (GEI) on PAH-DNA adducts in newborns and mothers
AACR Meeting Abstracts 2007 2007: 829.  

Logan Spector, Stephen Hecht, Simona Ognjanovic, Steven Carmella, and Julie Ross
Detection of cotinine in newborn dried blood spots
AACR Meeting Abstracts 2007 2007: 830.  

Robert Turesky, Jian-Min Yuan, Renwei Wang, Sabrina Peterson, and Mimi Yu
Urinary excretion of the carcinogenic heterocyclic amine 2-amino-9H-pyrido[2,3-b]indole (A{alpha}C) in smokers
AACR Meeting Abstracts 2007 2007: 831.  

Siyi Zhang, Peter Villalta, Mingyao Wang, and Stephen Hecht
Detection and quantitation of acrolein-derived 1,N2-propanodeoxyguanosine adducts in human lung using liquid chromatography-tandem mass spectrometry
AACR Meeting Abstracts 2007 2007: 832.  

Lee Yong, Alice Sigurdson, Elizabeth Ward, Martha Waters, Elizabeth Whelan, Martin Petersen, Elaine Ron, Marilyn Ramsey, Parveen Bhatti, and James Tucker
Chromosome translocations and cosmic sources of ionizing radiation: The NIOSH-NCI airline pilot biomarker study
AACR Meeting Abstracts 2007 2007: 833.  

David Araten and Kimberly DiTata
A quantitative analysis of the mutation rate in PIG-A using lymphocytes from human blood samples
AACR Meeting Abstracts 2007 2007: 834.  

Marco Peluso, Armelle Munnia, Petcharin Srivatanakul, Suleeporn Sangrajrang, Adisorn Jedpiyawongse, and Paolo Boffetta
Thermal dietary oxidation and malondialdehyde-deoxyguanosine
AACR Meeting Abstracts 2007 2007: 835.  

Joshua Muscat, Wayne Kleinman, Steven Colosimo, and John Richie
Cigarette tar and nicotine levels and biomarkers of oxidative stress
AACR Meeting Abstracts 2007 2007: 836.  

Reetta Holmila, Jette Bornholdt, Henrik Wolff, Pirjo Heikkila, Torben Steiniche, Michael Dictor, Annie Schmaus, Johnni Hansen, Daniele Luce, Hakan Wallin, and Kirsti Husgafvel-Pursiainen
Molecular changes in sino-nasal cancer related to wood dust exposure: TP53 mutations and COX-2 expression.
AACR Meeting Abstracts 2007 2007: 837.  

Ruey-Hong Wong, Shu-Yuan Chang, Shu-Wei Ho, Pei-Lin Huang, Yi-Jie Liu, and Hong-Shen Lee
Polymorphisms in metabolic GSTP1 and DNA repair XRCC1 and TP53 genes with an increased risk of DNA damage in pesticide-exposed fruit growers
AACR Meeting Abstracts 2007 2007: 838.  

Radim Sram, Olena Beskid, Andrea Rossnerova, Pavel Rossner, and Ivo Solansky
Chromosomal aberrations by FISH whole chromosome painting as biomarker of air pollution exposure to carcinogenic PAHs
AACR Meeting Abstracts 2007 2007: 839.  

Juan Cheng, Shuguang Leng, Yong Niu, Haishan Li, Linyuan Zhang, Huawei Duan, Xuemiao Liang, Bin Li, and Yuxin Zheng
DNA repair capacity is associated with chromosomal damage in peripheral lymphocytes among coke-oven workers
AACR Meeting Abstracts 2007 2007: 840.  

Pavel Rossner, Vlasta Svecova, Alena Milcova, Zdena Lnenickova, Ivo Solansky, and Radim Sram
Oxidative stress markers in bus drivers
AACR Meeting Abstracts 2007 2007: 841.  

Diet, Body Mass Index, and Cancer: Poster Presentations:Back

Panagiota Mitrou, Victor Kipnis, Jill Reedy, Amy Subar, Anne Thiebaut, Doug Midthune, Elisabet Wirfalt, Michael Leitzmann, Traci Mouw, Albert Hollenbeck, and Arthur Schatzkin
Mediterranean dietary pattern and cancer incidence: results from the NIH-AARP diet and health study
AACR Meeting Abstracts 2007 2007: 842.  

Charlotte Atkinson, Katherine Newton, Erin Aiello, Frank Stanczyk, and Johanna Lampe
Equol production in relation to hormones and mammographic breast density among premenopausal women in the United States
AACR Meeting Abstracts 2007 2007: 843.  

Jennifer Kelly, Jonathan Friedberg, Laura Calvi, Edwin van Wijngaarden, and Susan Fisher
Vitamin D insufficiency in patients with newly diagnosed lymphoma
AACR Meeting Abstracts 2007 2007: 844.  

Janneke Hogervorst, Leo Schouten, Erik Konings, Sandra Goldbohm, and Piet van den Brandt
A prospective study of dietary acrylamide intake and renal cell cancer
AACR Meeting Abstracts 2007 2007: 845.  

Han Liu, Christopher Wood, Jie Lin, Surena Matin, Nizar Tannir, and Xifeng Wu
Dietary folate intake and risk of renal cell carcinoma: a case-control analysis
AACR Meeting Abstracts 2007 2007: 846.  

Kenneth Bogen, June Chan, Garrett Keating, Leslie Paine, Ernest Simms, Elizabeth Holly, and James Felton
Prostate-specific antigen levels and dietary PhIP in African Americans: A prospective clinic-based study
AACR Meeting Abstracts 2007 2007: 847.  

gong yang, Xiao-Ou Shu, Honglan Li, Wong-Ho Chow, Yu-Tang Gao, and Wei Zheng
Soy food consumption and risk of colorectal cancer in women
AACR Meeting Abstracts 2007 2007: 848.  

Neal Freedman, Yikyung Park, Amy Subar, Albert Hollenbeck, Michael Leitzmann, Arthur Schatzkin, and Christian Abnet
Fruit and vegetable intake and head and neck cancer in a large United States prospective cohort study.
AACR Meeting Abstracts 2007 2007: 849.  

Lesley Butler, Renwei Wang, Woon-Puay Koh, Mariana Stern, and Mimi Yu
Fatty acid intake on colorectal cancer risk: The Singapore Chinese Health Study
AACR Meeting Abstracts 2007 2007: 850.  

Kwang-Pil Ko, Jin Gwack, Yeonju Kim, Sue Kyung Park, Daehee Kang, Soung-Hoon Chang, Hai-Rim Shin, and Keun-Young Yoo
Dietary factors and lung cancer risk from the KMCC study: Potential protective effect of soy products in Korea
AACR Meeting Abstracts 2007 2007: 851.  

Sabrina Peterson, Can-lan Sun, Woon Puay Koh, Robert Turesky, and Mimi Yu
Coffee intake and risk of colorectal cancer in Singapore Chinese
AACR Meeting Abstracts 2007 2007: 852.  

Donghui Li, Manal Hassan, Rabia Khan, Melissa Bondy, James Abbruzzese, and Rena Day
Dietary micronutrient intakes and risk of pancreatic cancer
AACR Meeting Abstracts 2007 2007: 853.  

Brenda Bongaerts, Anton de Goeij, Piet van den Brandt, R. Goldbohm, and Matty Weijenberg
Moderate alcohol consumption, alcoholic beverages and risk of colorectal cancer
AACR Meeting Abstracts 2007 2007: 854.  

Jasmeet Gill, Lynne Wilkens, Kami White, and Laurence Kolonel
Biomarkers of selenium, carotenoids, and vitamin E intake and risk of prostate cancer: the Multiethnic Cohort
AACR Meeting Abstracts 2007 2007: 855.  

Ute Nothlings, Suzanne Murphy, Lynne Wilkens, Brian Henderson, and Laurence Kolonel
Flavonols and pancreatic cancer risk: The Multiethnic Cohort Study
AACR Meeting Abstracts 2007 2007: 856.  

Elizabeth Poole, John Whitton, John Potter, and Cornelia Ulrich
Interaction between intakes of B vitamins and NSAID use on risk of colorectal adenoma
AACR Meeting Abstracts 2007 2007: 857.  

Stella Koutros, Amanda Cross, Dale Sandler, Jane Hoppin, Xiaomei Ma, Tongzhang Zheng, Michael Alavanja, and Rashmi Sinha
Meat and meat mutagens and risk of prostate cancer in the Agricultural Health Study cohort
AACR Meeting Abstracts 2007 2007: 858.  

Brian Chiu, Bhavana Dave, Mary Ward, Aaron Blair, Angela Fought, Susan Gapstur, Smrati Jain, Shelia Zahm, and Dennis Weisenburger
Diet and risk of t(14;18)-defined subgroups of non-Hodgkin lymphoma
AACR Meeting Abstracts 2007 2007: 859.  

Jennifer-Hsiang-Ling Lin, I-Min Lee, Nancy Cook, Jacob Selhub, JoAnn Manson, Julie Buring, and Shumin Zhang
Plasma folate, vitamin B6, vitamin B12 and risk of breast cancer in women
AACR Meeting Abstracts 2007 2007: 860.  

Adeyinka Laiyemo, Gwen Murphy, Leah Sansbury, Zhuoqiao Wang, Paul Albert, Arthur Schatzkin, and Elaine Lanza
Polyp characteristics, diet, lifestyle factors and high-risk colorectal adenoma recurrence in the polyp prevention trial
AACR Meeting Abstracts 2007 2007: 861.  

Zemin Wang, Yuntian Tang, Qingsong Cai, Li Xu, Guiju Sun, Xu Hu, Lili Tang, Weimin Gao, Stephen Cox, and Jia-Sheng Wang
Antioxidant vitamins and green tea polyphenols and risk of esophageal squamous cell carcinoma in Huaian, China
AACR Meeting Abstracts 2007 2007: 862.  

Paolo Boffetta, Mia Hashibe, and On Behalf Of INHANCE Consortium
Alcohol drinking in never-tobacco users and cigarette smoking in never drinkers: pooled analysis in the International Head and Neck Cancer Epidemiology (INHANCE) consortium
AACR Meeting Abstracts 2007 2007: 863.  

Maureen Murtaugh, Jennifer Herrick, Carol Sweeney, Kathy Baumgartner, Anna Guiliano, Tim Byeres, and Martha Slattery
Diet composition and breast cancer risk in Hispanic andWNH women from the Four Corners States
AACR Meeting Abstracts 2007 2007: 864.  

Amit Algotar, M. Stratton, Patricia Thompson, James Ranger-Moore, Steven Stratton, Gina Schwartzberg, Janet Haines, Kathy Monroe, Frances Minter, and Frederick Ahmann
Obesity as a risk factor for prostate cancer progression in the watchful waiting study
AACR Meeting Abstracts 2007 2007: 865.  

Christian Abnet, Neal Freedman, Albert Hollenbeck, Joseph Fraumeni, Michael Leitzmann, and Arthur Schatzkin
A prospective study of BMI and risk of esophageal and gastric adenocarcinoma
AACR Meeting Abstracts 2007 2007: 866.  

Gertraud Maskarinec, Jasmeet Gill, Brian Henderson, and Laurence Kolonel
Overweight, obesity, and the metabolic syndrome as risk factors for Non-Hodgkin lymphoma: The Multiethnic Cohort
AACR Meeting Abstracts 2007 2007: 867.  

Christy Woolcott, Christine Friedenreich, Linda Cook, Kerry Courneya, Martin Yaffe, Norman Boyd, Tim Terry, Rollin Brant, Anne McTiernan, Heather Bryant, and Anthony Magliocco
Adiposity and mammographic density
AACR Meeting Abstracts 2007 2007: 868.  

Yeonju Kim, Sue Park, So-Hee Han, Ji-Yeob Choi, Kyoung-Mu Lee, Dong-Hyun Kim, Yun-Chul Hong, Eun-Hee Ha, Se-Hyun Ahn, Dong-Young Noh, Daehee Kang, and Keun-Young Yoo
Serum high-density lipoprotein cholesterol and breast cancer risk in a case-control study in Korea
AACR Meeting Abstracts 2007 2007: 869.  

Young Kim, David Jacobs, Myron Gross, Raymond Bergan, Peter Gann, Kiang Liu, and Susan Gapstur
Association of serum carotenoid level with serum insulin-like growth factor (IGF)-1 and IGF-binding protein (IGFBP)-3 levels in black and white men
AACR Meeting Abstracts 2007 2007: 870.  

Alana Hudson, Joel Weissfeld, Francesmary Modugno, John Wilson, Rhobert Evans, Gretchen Gierach, Jennifer Simpson, and Victor Vogel
The 6:3 PUFA ratio and serum estradiol in postmenopausal women
AACR Meeting Abstracts 2007 2007: 871.  

DNA Damage and Repair in Carcinogenesis: Poster Presentations:Back

Bo Hang, Ping Wang, and Anton Guliaev
Metal inhibition of human DNA glycosylases in the base excision repair pathway
AACR Meeting Abstracts 2007 2007: 872.  

Feng Liu and Frank Meyskens
Microphthalmic transcription factor(MITF) regulates cellular response to reactive oxygen species through transcriptional regulation of Ape1/Ref1
AACR Meeting Abstracts 2007 2007: 873.  

Nicola Cooley, Andrew Povey, and Rhoderick Elder
Knockdown of DNA response genes in DNA glycosylase proficient and deficient mouse fibroblasts.
AACR Meeting Abstracts 2007 2007: 874.  

Bradford Brooks, Travis O'Brien, and Steven Patierno
Base excision repair and Cr(III): failure to process endogenous lesions by high fidelity repair.
AACR Meeting Abstracts 2007 2007: 875.  

Ayumi Kato, Anna Kinoshita, Min Wei, Kenichiro Doi, Keiichirou Morimura, and Hideki Wanibuchi
Carcinogenicity of dimethylarsinic acid in Ogg1-deficient mice
AACR Meeting Abstracts 2007 2007: 876.  

Sujata Choudhury and Rabindra Roy
1, N6-Ethenoadenine, a mutagenic and potential damage for human cancer, is repaired by long patch branch of base excision repair in human cells
AACR Meeting Abstracts 2007 2007: 877.  

Paola Monti, Yari Ciribilli, Paola Menichini, Debora Russo, Alessandra Bisio, Alberto Inga, Gilberto Fronza, and Barry Gold
Rev3 (pol {zeta}) is involved in the mutation fixation process of Me-lex induced lesions
AACR Meeting Abstracts 2007 2007: 878.  

Jong-Heum Park, Dipti Mangal, Seon Hwa Lee, Ian Blair, and Trevor Penning
Agreement between the comet assay and LC/MS detection of 8-Oxo-2’-deoxyguanosine (8-oxo-dGuo) in human lung adenocarcinoma (A549) cells: role for the metabolic activation of PAH by Aldo-Keto Reductases (AKRs)
AACR Meeting Abstracts 2007 2007: 879.  

Duanjun Tan, Ramona Dumitreascu, David Goerlitz, Roy Orden, Jinguo Chen, Radoslav Goldman, and Peter Shields
Associations between cigarette smoking and mitochondrial abnormalities in buccal cells
AACR Meeting Abstracts 2007 2007: 880.  

Ki-Hyuk Shin, Reuben H. Kim, Mo K. Kang, Roy H. Kim, Steve J. Kim, Philip K. Lim, Ji Min Yochim, Marcel A. Baluda, and No-Hee Park
Heterogeneous nuclear ribonucleoprotein G (hnRNP G) promotes the fidelity of DNA end-joining activity
AACR Meeting Abstracts 2007 2007: 881.  

Mette Praetorius-Ibba, Qi-en Wang, Gulzar Wani, Mohamed El-Mahdy, Qianzheng Zhu, Song Qin, Srinivas Patnaik, Qun Zhao, and Altaf Wani
Role of Claspin in regulating nucleotide excision repair
AACR Meeting Abstracts 2007 2007: 882.  

Kenichiro Doi, Min Wei, Takayuki Yunoki, Anna Kinoshita, Keiichirou Morimura, Shoji Fukushima, and Hideki Wanibuchi
Effect of a genotoxic carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine on the variation of 3D-microarray-determined gene expression in colonic adenocarcinomas of rats initiated with azoxymethane
AACR Meeting Abstracts 2007 2007: 883.  

Suryakant Niture, Catalin Doneanu, Francis Ali-Osman, and Kalkunte Srivenugopal
Redox regulation on the house for GSTP1-1 in human cancers: glutathionylation of the reactive Cys47 alters protein structure and increases catalytic activity
AACR Meeting Abstracts 2007 2007: 884.  

Alexandra Miller
Transgenerational transmission of genetic damage by depleted uranium and tungsten alloy
AACR Meeting Abstracts 2007 2007: 885.  

Laura Hays, Dylan Zodrow, Jane Yates, Mark Deffebach, David Jacoby, James Pankow, and Grover Bagby
The role of fanconi anemia protein FANCD2 in lung carcinogenesis
AACR Meeting Abstracts 2007 2007: 886.  

Chuan Wang, Laura McMahon, Joel Lefferts, and Muriel Lambert
The Fanconi Anemia Protein, FANCA, interacts directly with the DNA repair protein, XPF, and with the structural protein, nonerythroid alpha spectrin
AACR Meeting Abstracts 2007 2007: 887.  

Melissa Baralt, Laura McMahon, and Muriel Lambert
Interaction of nonerythroid alpha spectrin with DNA containing interstrand cross-links and its functional importance
AACR Meeting Abstracts 2007 2007: 888.  

Ping Zhang, Jean Bourhis, Nicolas Dorvault, Yungan Tao, Maria Castedo, Didier Metivier, Guido Kroemer, and Eric Deutsch
Role of 53BP1 in double strand break recognition mechanisms and cell survival after exposure to ionizing radiation : relative p53 and Chk2 dependency
AACR Meeting Abstracts 2007 2007: 889.  

Young Do Yoo, In Tae Hwang, Jung Jin Kim, Seung Baek Lee, Ah Ram Na, Bong Sang Yoo, Kee-Ho Lee, Jun Suk Kim, and Young Min Chung
Increased expression of reactive oxygen species modulator1 (Romo1) confers tumor cells to 5-FU resistance
AACR Meeting Abstracts 2007 2007: 890.  

Anita Patlolla, Donee' McAllister, and Paul Tchounwou
DNA damaging effects of potassium dichromate in peripheral blood leukocytes of Sprague-Dawley rats.
AACR Meeting Abstracts 2007 2007: 891.  

Stephen Kioko, Xuebiao Yao, Michael Powell, Aisha Rollins-Hairston, and Ward Kirlin
Nuclear translocation of the aryl hydrocarbon receptor in response to oxidative stress
AACR Meeting Abstracts 2007 2007: 892.  

Po-Hsiung Lin, Chia-Hua Lin, Chuan-Chen Huang, and Ming-Chieh Chuang
2,3,7,8-tetrachlorodibenzo-p-dioxin induces oxidative stress, poly(ADP-ribose) polymerase-1 activation, and DNA strand breaks in human breast carcinoma cell lines
AACR Meeting Abstracts 2007 2007: 893.  

Yuan-Wan Sun, Zhong-Lin Zhao, Joseph Guttenplan, Wieslawa Kosinska, Jacek Krzeminski, Shantu Amin, and Karam El-Bayoumy
Mutational spectra of trans-1,2-dihydroxy-1,2-dihydro-6-hydroxylaminochrysene (1,2-DHD-6-NHOH-C), a putative ultimate carcinogenic metabolite of the environmental mammary carcinogen 6-nitrochrysene (6-NC), in a lacI mammary epithelial cell line
AACR Meeting Abstracts 2007 2007: 894.  

Qi Wu and Karen Vasquez
The role of mismatch repair in processing DNA interstrand crosslinks in human cells
AACR Meeting Abstracts 2007 2007: 895.  

Kwang Seo, Jun Yin, Sushil Chandani,